Publications by authors named "Guozheng Yan"

Article Synopsis
  • Fecal incontinence (FI) is the inability to control fecal leakage, and the artificial anal sphincter (AAS) is typically used as a last resort treatment option.
  • The study investigates a new type of AAS called the biaxial actuated artificial anal sphincter (BAAS), which offers real-time feedback on intestinal pressure and has a reliable power source.
  • In long-term experiments with piglets, the BAAS demonstrated effective feces control, with 65.79% accuracy in detecting when the piglets could defecate, enhancing the understanding of defecation mechanisms and guiding future AAS developments.
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Piezoresistive pressure sensors have broad applications but often face accuracy challenges due to temperature-induced drift. Traditional compensation methods based on discrete data, such as polynomial interpolation, support vector machine (SVM), and artificial neural network (ANN), overlook the thermal hysteresis, resulting in lower accuracy. Considering the sequence-dependent nature of temperature drift, we propose the RF-IWOA-GRU temperature compensation model.

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Article Synopsis
  • A capsule robot (CR) has been developed for potential use as a less invasive alternative to traditional colonoscopy, with a focus on understanding the friction forces involved in its movement.
  • The study measures the coefficient of friction (COF) for three materials used in the CR under various conditions, leading to the creation of a general COF equation that successfully predicts traction force and locomotion resistance.
  • This COF equation holds significant importance for improving the control and efficiency of the CR during its operation in the colon.
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Background: Wireless power transmission for capsule robots has always posed challenges due to the unpredictable postures.

Methods: A radial transmitting coil with a novel ferrite structure is proposed, which consists of two parts with the function of converging magnetic induction lines and reducing magnetic leakage. To improve the flux density, uniformity, and shielding effectiveness, the design parameters are discussed and optimized on the basis of analytical calculations and simulation analysis.

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Background: The artificial anal sphincter (AAS) system has gained significant attention as a solution for treating fecal incontinence (FI). It relies on transcutaneous energy transfer (TET) as its primary energy source. However, changes in posture or biological tissue can cause misalignment of the coil, resulting in unstable power reception.

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Article Synopsis
  • * The simulation shows that the sensor system performs well during clamping and fecal accumulation, with optimal sensing occurring at a roll angle between 20° and 40°, and a small error margin of 10%-20% compared to in vitro tests.
  • * Overall, the study enhances understanding of the device's interaction with the intestinal environment, aiming to improve the sensor performance of the artificial anal sphincter for future research applications.
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High permeability material, especially the ferrite, has been widely used in wireless power transfer (WPT) to enhance the power transfer efficiency (PTE). However, for the WPT system of inductively coupled capsule robot, the ferrite core is solely introduced in power receiving coil (PRC) configuration to enhance the coupling. As for the power transmitting coil (PTC), very few studies focus on the ferrite structure design, and only the magnetic concentrating is taken into account without careful design.

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Capsule robots capable of taking wireless power-transfer systems for diagnosis in the intestine enable the ability to avoid invasive detection, which causes damage to tissue. A targeted therapy capsule robot based on a wireless power-transfer system could move actively in the intestine, implementing diseases detection and drug delivery. Compared with traditional telescope, the capsule robot explores without pain to patients.

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Monitoring bodily pressure could provide valuable medical information for both doctors and patients. Long-term implantation of in vivo sensors is highly desirable in situations where perception reconstruction is needed. In particular, for fecal incontinence, artificial anal sphincters without perceptions could not remind patients when to defecate and even cause ischemic tissue necrosis due to uncontrolled clamping pressure.

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Power receiving coils (PRCs) with ferrite cores are widely used in wireless power transfer (WPT) for capsule robots (CRs) to enhance the power transfer efficiency (PTE). However, due to the large demagnetizing factor, the traditional one-dimensional hollow cylindrical ferrite core has its limitations in volume and performance improvement, which needs to be reconsidered. To this end, we propose a novel PRC equipped with a delicate, lightweight, and more efficient ferrite core structure in this paper.

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Background: Artificial organs are playing an increasingly important role in medical field. Artificial anal sphincter, as an example, is a widely used medical device for fecal incontinence. Though it could help patients maintain continence, the issue of perception reconstruction is still unsolved, which means that patients cannot control defecation as desired.

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Background: The wireless power transfer system (WPTS) is a promising way to continuously provide efficient and stable power for gastrointestinal capsule robots with active movement ability.

Methods: The proposed WPTS using an optimised planar square spiral transmitting coil pair with space-saving structure can flexibly adjust the distance between the coils according to the patient's condition, and thus has better applicability. To improve power transfer efficiency and uniformity of the generated magnetic field, design parameters are discussed and optimised based on the analytical calculation and simulation analysis.

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Background: Artificial anal sphincter (AAS), as an advanced device, has been widely investigated by researchers around world. But the reliability of the structure is still unsatisfactory according to clinical results. What's more, the previous AAS systems are lack the ability of rectal perception as native anal sphincter, which fails to guarantee the safety of the blood supply.

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An artificial anal sphincter is a device to help patients with fecal incontinence rebuild the ability to control the excrement through the anus. In this article, an artificial anal sphincter based on a novel clamping mechanism (AASNCM) is proposed to improve the safety and reliability. The AASNCM, which is powered by a transcutaneous energy transfer system, consists of a novel clamping mechanism, a receiving coil and a control unit.

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In order to improve the reliability, safety and whole digestive applicability of the gastrointestinal microrobot (GMR), a novel inchworm-like GMR is proposed in this paper. The expanding mechanism of the robot adopts an overlapping expanding arm structure. This structure increases the variable diameter ratio (ratio of fully expanded diameter to fully folded diameter) of the robot to 3.

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Intestinal-related diseases all around the world are increasing nowadays, and gradually become stubborn diseases threatening human health, and even lives. Diagnosis methods have attracted more and more attention. This article concerns a non-invasive way, a novel micro-robot, to diagnose intestinal diseases.

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Wireless capsule endoscopy (WCE) is noninvasive, painless, and riskless on detection for gastrointestinal disease. It attracts increasing attention. Wireless power transfer (WPT) technology is utilized to supply power for WCE.

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A wearable wireless health monitoring system for drug addicts in compulsory rehabilitation centers was proposed. The system can continuously monitor multiple physiological parameters of drug addicts in real time, and issue early warning information when abnormal physiological parameters occur, so as to play the role of timely medical practice. In addition, this study proposes a convolutional neural network (CNN)model, which can evaluate the health status of drug addicts based on multiple physiological parameters.

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While fecal incontinence (FI) is not fatal, it can dramatically decrease the patient's quality of life. An artificial anal sphincter (AAS) is an implantable device that treats FI by replacing a diseased or damaged anal sphincter, thus allowing the patient's continence to be maintained. Here, we report a novel implantable puborectalis-like artificial anal sphincter (PAAS) that replicates rectal perception and has a low risk of ischemia necrosis.

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Objective: The evaluation of GI-pill gastrointestinal electronic capsule for colonic transit test in patients with slow transit constipation (STC) was studied.

Materials And Methods: STC patients (n = 162) were randomly divided into experimental group (n = 84, orally taken GI-pill gastrointestinal electronic capsule and X-ray granule capsule) and control group (n = 78, orally taken X-ray granule capsule). Comparison of the time in colonic transit test between the two groups was conducted.

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In order to make the gastrointestinal microrobot (GMR) expand and anchor in the gastrointestinal tract reliably, a novel expanding mechanism of the GMR is proposed in this paper. The overlapping expanding arm is designed to be used to increase the variable diameter ratio (ratio of fully expanded diameter to fully folded diameter) to 3.3, which makes the robot more adaptable to the intestinal tract of different sections of the human body.

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A tether-less inchworm-like capsule robot (ILCR) is promising to enable a non-invasive exploration of the colon, while existing ILCRs show barely satisfactory movement performance because the colon environment is nonstructural. In this current study, we develop an enhanced ILCR based on a design rule of maximizing the achievable periodic stroke and minimizing the body length, with the aim of improving movement performance. By designing an axial compact expanding mechanism (EM), employing a novel linear mechanism (LM), and integrating a hollow-cylinder-like power source based on wireless power transmission (WPT), the enhanced ILCR achieves a periodic stroke of 38 mm within a small body length of 33 mm.

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Puborectalis-like artificial anal sphincter (PAAS) is an innovative new type of artificial anal sphincter (AAS). It overcomes many drawbacks and inadequacies of various previous AASs, and it has successfully been implanted in vivo for almost 3 weeks. During in vivo testing, PAAS shows its ability to retain continence with low risk of ischemia necrosis, and somehow truly helps to remodel rectal perception.

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Robotic colonoscopy is an efficient examination method for finding malignant tumour in its early stage. This research developed a novel robotic endoscope with 13 mm diameter, 105 mm length and 22.3 g weight.

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Artificial anal sphincter (AAS) is an in situ implanted device that acts as a treatment for fecal incontinence regardless of etiology by augmenting the incompetent sphincteric structures. However, AAS is impeded from becoming a valid therapy by its high rate of ischemic complication and malfunction. This article presents an original puborectalis-like artificial anal sphincter (PAAS) that features a low risk of ischemia necrosis and rectal perception remodeling.

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