Publications by authors named "Guoyan Zhong"
Curdlan's application is constrained by high gelation concentration, poor water solubility, and incompatibility with other polysaccharides. To address these limitations, this study investigated the effects of different concentrations (0.05-0.
View Article and Find Full Text PDFDesigning fluorescent probe for detecting carboxylesterase 1 is remains challenging. Herein, a red emission human carboxylesterase 1 (CES1) probe (CAE-FP) was synthesized based on fluorescent protein chromophore. Probe CAE-FP can specific detect human CES1 with high selectively.
View Article and Find Full Text PDFArticle Synopsis
- Microenvironment factors like viscosity, polarity, and pH significantly impact the behavior of molecules, influencing cellular functions and potentially leading to diseases.
- Recent advancements in chemicobiology have highlighted the development of viscosity-sensitive fluorescent probes that are effective for imaging and studying biomembranes and specific organelles like mitochondria and lysosomes.
- This review summarizes various viscosity-sensitive chemosensors that have been created, focusing on their applications in quantifying intracellular viscosity using methods such as fluorescence lifetime imaging (FLIM) and ratiometric imaging.
Recent development of synthetic probes for detection of hypochlorous acid/hypochlorite.
Spectrochim Acta A Mol Biomol Spectrosc
October 2020
Article Synopsis
- Hypochlorous acid/hypochlorite (HOCl/OCl) is a key reactive oxygen species involved in various health processes, but abnormal levels are linked to diseases.
- The development of fluorescent probes for detecting HOCl/OCl is crucial, with numerous probes created over the past decade for in vitro and in vivo use.
- Despite advancements, challenges remain in creating specific and sensitive near-infrared (NIR) fluorescent probes for detecting endogenous OCl and for bioimaging at the subcellular level.