Publications by authors named "Guoxiong Chen"

Sand rice (), widely distributed in Central Arid Asia and prevalent in the sand dunes of northern China, presents a promising potential as a climate-resilient crop. The plasticity of hypocotyl growth is the key trait for sand rice to cope with wind erosion and sand burial, ensure seedling emergence, and determine plant architecture. In this study, we assessed the overall hypocotyl phenotype of six sand rice elite lines, which were collected from different regions of northern China, and selected by our group over past decade through common garden trials.

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Quinoa (Chenopodium quinoa, 2n = 4x = 36), a super pseudocereal crop, has been introduced into China nearly 60 years. Many excellent varieties have been developed through massive selection; however, few are developed through mutagenesis breeding. In this study, the 'Longli-4' variety, locally cultivated in Gansu province, Northwest China, was selected for experimentation.

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The lithosphere, as the outermost solid layer of our planet, preserves a progressively more fragmentary record of geological events and processes from Earth's history the further back in time one looks. Thus, the evolution of lithospheric thickness and its cascading impacts in Earth's tectonic system are presently unknown. Here, we track the lithospheric thickness history using machine learning based on global lithogeochemical data of basalt.

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(WYMV) is a pathogen transmitted into its host's roots by the soil-borne vector . and genes protect the host from the significant yield losses caused by the virus, but the mechanistic basis of these resistance genes remains poorly understood. Here, it has been shown that and act within the root either by hindering the initial movement of WYMV from the vector into the root and/or by suppressing viral multiplication.

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Quinoa () is a well-known climate-resilient crop and has been introduced into multiple marginal lands across the world, including China, to improve food security and/or balanced nutrient supplies. Conventional breeding has been widely applied in the selection and breeding of quinoa varieties in China since 1980s; however, few studies have been implemented on the genetic variances among different varieties developed by diversity breeding objectives. In this study, the phenotypic and genetic differences between two varieties (Longli-4 and CA3-1) from China were systematically analyzed.

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Renal clear cell carcinoma (KIRC) is one malignancy whose development and prognosis have been associated with aberrant DHRS7 expression. However, the catalytic activity and pathophysiology of KIRC are poorly understood, and no sensitive tumor biomarkers have yet been discovered. In our study, we examined the significant influence of DHRS7 on the tumor microenvironment (TME) and tumor progression using an overall predictable and prognostic evaluation approach.

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Reconstructing historical atmospheric oxygen (O) levels at finer temporal resolution is a top priority for exploring the evolution of life on Earth. This goal, however, is challenged by gaps in traditionally employed sediment-hosted geochemical proxy data. Here, we propose an independent strategy-machine learning with global mafic igneous geochemistry big data to explore atmospheric oxygenation over the last 4.

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Article Synopsis
  • Sand rice (Agriophyllum squarrosum) is a plant found in arid regions of Asia, making it a great subject to study how plants adapt to desert environments due to its significant variety among individuals.
  • This study examined the size of seeds from 68 different populations and found that both seed size and weight are influenced largely by long-term climate factors, particularly varying levels of precipitation across regions.
  • Additionally, certain groups of larger seeds demonstrated greater competitiveness and adaptability in drier areas, suggesting they may be beneficial for future domestication efforts.
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  • Sand rice is a highly nutritious crop with potential climate resilience, offering rich proteins, essential amino acids, and beneficial compounds like phenolics.
  • Its historical consumption spans over 1300 years, but recent breeding efforts have increased yields significantly, with some genotypes producing up to 1295.5 kg/ha.
  • Despite its potential, research on sand rice is limited compared to other crops like quinoa, highlighting the need for further scientific exploration to unlock its nutritional and commercial benefits.
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Myocardial ischemia reperfusion (MIR) injury negatively affects the prognosis of acute myocardial infarction (AMI), while effective suppression of MIR injury remains a largely unmet clinical need. Interferon regulatory factors (IRF) are key players in chronic cardiac disorders such as cardiac remodeling. However, their roles in acute MIR injury remain largely unknown.

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Background: This study investigated the effects of the intracoronary injection of nicorandil and tirofiban on myocardial perfusion and short-term prognosis in elderly patients with acute ST-segment elevation myocardial infarction (STEMI) after emergency percutaneous coronary intervention (PCI).

Methods: Seventy-eight STEMI patients with age >65 years who underwent emergency PCI were consecutively enrolled. These patients received conventional PCI and were randomly divided into a control group and a treatment group (=39 per group).

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As a technique capable of rapid, nondestructive, and multi-elemental analysis, portable X-ray fluorescence (pXRF) has applications to mineral exploration, environmental evaluation, and archaeological analysis. However, few applications have been conducted in the smelting industry especially when analyzing the metal concentration in ore concentrate samples. This research analyzed the effectiveness of using pXRF in determining the metal concentration in Fe concentrate.

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  • Sand rice (Agriophyllum squarrosum) is being studied as a potential crop due to climate change and food security concerns, and modifying its weedy traits is essential for domestication.
  • Researchers isolated a trichomeless mutant of sand rice using ethyl methanesulfonate (EMS) and found that its traits are controlled by a single recessive gene.
  • Genetic analysis showed that the mutation affects only a small number of genes, particularly those related to lipid transport and metabolism, suggesting that the Astcl1 protein plays a key role in trichome development and cuticle synthesis in sand rice.
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The cuticle coats the primary aerial surfaces of land plants. It consists of cutin and waxes, which provide protection against desiccation, pathogens and herbivores. Acyl cuticular waxes are synthesized via elongase complexes that extend fatty acyl precursors up to 38 carbons for downstream modification pathways.

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The hydrophobic cuticle covers the surface of the most aerial organs of land plants. The barley mutant (), which is hypersensitive to drought, is unable to accumulate a sufficient quantity of cutin in its leaf cuticle. The mutated locus has been mapped to a 0.

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The naturally occurring wild barley mutant eibi1/hvabcg31 suffers from severe water loss due to the permeable leaf cuticle. Eibi1/HvABCG31 encodes a full ATP-binding cassette (ABC) transporter, HvABCG31, playing a role in cutin deposition in the elongation zone of growing barley leaves. The eibi1 allele has pleiotropic effects on the appearance of leaves, plant stature, fertility, spike and grain size, and rate of germination.

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  • - Braya humilis, a plant in the Brassicaceae family, is highly adaptable to diverse climates, found from northern Asia to arctic-alpine areas in North America, with a focus on the Qinghai-Tibetan Plateau in China.
  • - Through sequencing its transcriptome, researchers generated over 46,000 unigenes and identified 381 core orthologous genes, including 39 related to stress responses, showing a high level of conservation with its close relative, Arabidopsis thaliana.
  • - The study found that certain genes in B. humilis believed to help it adapt to saline and osmotic stress are conserved in both sequence and function compared to Arabidopsis, suggesting evolutionary adaptations are aided
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  • * Researchers identified over 105,000 single nucleotide polymorphisms (SNPs) and found that specific gene variations related to DNA recombination helped the semi-arid population survive its environment.
  • * Four candidate genes linked to heat tolerance, seed size, and flowering were analyzed across various natural sand rice populations, revealing unique alleles in the semi-arid population that could be beneficial for future breeding efforts.
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  • * This mutant gene is located on chromosome 3HL, specifically in a 1.3-cM region between the genes MLOC_10972 and MLOC_69561.
  • * The wild type version of this gene likely plays a role in the synthesis pathway of β-diketone compounds, which contribute to the plants' waxy appearance.
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Obesity, diabetes and fatty liver disease are extremely common in leptin-resistant patients. Dysfunction of leptin or its receptor is associated with obesity. The present study aimed to assess the effects of intramuscular injection of exogenous leptin or its receptor on fat deposition and leptin-insulin feedback regulation.

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  • Climate change has significantly influenced ecosystem shifts in the Asian interior, leading to frequent changes between grasslands and deserts over time.
  • The study investigated the population dynamics of Agriophyllum squarrosum, a pioneer plant in mobile sand dunes, revealing its long history of colonization related to climatic changes and glaciations.
  • Findings indicate that the monsoonal climate aided the plant's expansion and that desertification in areas like the Qinghai-Tibetan Plateau is more ancient and may worsen with global warming, highlighting the need for exploring genetic resources for future crop development in dry lands.
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Reaumuria soongorica and sand rice (Agriophyllum squarrosum) belong to the clade of Caryophyllales and are widely distributed in the desert regions of north China. Both plants have evolved many specific traits and adaptation strategies to cope with recurring environmental threats. However, the genetic basis that underpins their unique traits and adaptation remains unknown.

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Both of the uplift of Qinghai-Tibet Plateau (QTP) and the development of East Asian monsoon system (EAMS) could have comprehensively impacted the formation and evolution of Arid Central Asia (ACA). To understand how desert plants endemic to ACA responded to these two factors, we profiled the historical population dynamics and distribution range shift of a constructive desert shrub Reaumuria soongarica (Tamaricaceae) based on species wide investigation of sequence variation of chloroplast DNA and nuclear ribosomal ITS. Phylogenetic analysis uncovered a deep divergence occurring at ca.

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The cuticle covers the aerial parts of land plants, where it serves many important functions, including water retention. Here, a recessive cuticle mutant, eceriferum-ym (cer-ym), of Hordeum vulgare L. (barley) showed abnormally glossy spikes, sheaths, and leaves.

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