The study on agitation and structure of orbitofrontal cortex subregion in first-episode drug-naïve patients with schizophrenia.

Agitation is one of the core symptoms of schizophrenia. The occurrence of agitation may be related to orbitofrontal cortex dysfunction. However, due to methodological heterogeneity, the relationship between agitation and orbitofrontal cortex subregions remains unclear.

Antibacterial activity evaluation of a novel K3-specific phage against Acinetobacter baumannii and evidence for receptor-binding domain transfer across morphologies.

Acinetobacter baumannii (A. baumannii) poses a serious public health challenge due to its notorious antimicrobial resistance, particularly carbapenem-resistant A. baumannii (CRAB).

Polystyrene nanoplastics induce cell type-dependent secondary wall reinforcement in rice (Oryza sativa) roots and reduce root hydraulic conductivity.

Nanoplastics (NPs) have been demonstrated the ability to penetrate plant roots and cause stress. However, the extent of NPs penetration into various root tissues and the corresponding plant defense mechanisms remain unclear. This study examined the penetration and accumulation patterns of polystyrene nanoplastics (PS-NPs) in different cell types within rice roots, and explored how the roots quickly modify their cell wall structure in response.

Striatum and globus pallidus structural abnormalities in schizophrenia: A retrospective study of the different stages of the disease.

Background: The basal ganglia are important structures for the release of dopamine in the limbic circuits of the midbrain, and the striatum and globus pallidus are the major nuclei of the basal ganglia, and the dysfunction of these regions has been the basis of many models that have attempted to explain the underlying mechanisms of schizophrenia symptoms. The purpose of this study was to investigate the changes in the volume of the striatum subregion and globus pallidus in three different stages of schizophrenia, and to analyze whether these volume changes were related to antipsychotic drugs and schizophrenia symptoms.

Methods: In this study, we investigated the volume of the striatum and globus pallidus in patients with schizophrenia at three different stages.

New Awareness of the Interplay Between the Gut Microbiota and Circadian Rhythms.

Circadian rhythms influence various aspects of the biology and physiology of the host, such as food intake and sleep/wake cycles. In recent years, an increasing amount of genetic and epidemiological data has shown that the light/dark cycle is the main cue that regulates circadian rhythms. Other factors, including sleep/wake cycles and food intake, have necessary effects on the composition and rhythms of the gut microbiota.

The rate-limiting procedure of 3D DNA walkers and their applications in tandem technology.

DNA walkers, artificial dynamic DNA nanomachines, can mimic actin to move rapidly along a predefined nucleic acid track. They can generally be classified as one- (1D), two- (2D), and three-dimensional (3D) DNA walkers. In particular, 3D DNA walkers demonstrate amazing sustainable walking ability, strong enrichment ability, and fantastic signal amplification ability.

Volumes of hippocampal subfields suggest a continuum between schizophrenia, major depressive disorder and bipolar disorder.

Objective: There is considerable debate as to whether the continuum of major psychiatric disorders exists and to what extent the boundaries extend. Converging evidence suggests that alterations in hippocampal volume are a common sign in psychiatric disorders; however, there is still no consensus on the nature and extent of hippocampal atrophy in schizophrenia (SZ), major depressive disorder (MDD) and bipolar disorder (BD). The aim of this study was to verify the continuum of SZ - BD - MDD at the level of hippocampal subfield volume and to compare the volume differences in hippocampal subfields in the continuum.

Machine learning combined with MALDI-TOF MS has the potential ability to identify serotypes of the avian pathogen Riemerella anatipestifer.

Aim: Combining MALDI-TOF MS and machine learning to establish a new rapid method to identify two important serotypes of Rimerella anatipestifer.

Methods And Results: MALDI-TOF MS was performed on 115 R. anatipestifer strains (serotype 1, serotype 2, and other serotypes) to explore its ability to identify serotypes of R.

Endothelin receptor B enhances liver injury and pro-inflammatory responses by increasing G-protein-coupled receptor kinase-2 expression in primary biliary cholangitis.

Severe diseases like cirrhosis and liver failure can be developed from primary biliary cholangitis (PBC). Endothelin-2 (EDN2) and endothelin receptor B (EDNRB) are related to the pathogenesis of PBC. However, the roles of EDN2 and EDNRB in PBC-related liver injury and inflammation along with molecular mechanisms are poorly defined.

Electroconvulsive therapy efficacy in adolescents with mental illness: A retrospective comparison.

Background: There is limited evidence on the efficacy of electroconvulsive therapy (ECT) in adolescents with mental illness. The present study reported outcomes of adolescents with mental illness treated with ECT aimed at providing evidence for large-scale feasibility.

Objectives: The primary objective of this trial was to examine the differences in demographic and clinical data between responders and non-responders.

Insights into amphicarpy from the compact genome of the legume Amphicarpaea edgeworthii.

Amphicarpy (seed heteromorphy) is a unique and fascinating reproductive strategy wherein a single plant produces both aerial and subterranean fruits. This strategy is believed to be an adaptation to life under stressful or uncertain environments. Here, we sequenced and de novo assembled a chromosome-level genome assembly of the legume Amphicarpaea edgeworthii Benth.

[Effect of Fertilizer Reduction and Biochar Application on Soil Nitrogen Loss in Purple Upland].

This study seeks to clarify the effect of biochar application on nitrogen loss patterns and flux in purple arid sloping land, so as to provide a scientific basis for improving the quality of farmland and reducing the risk of agricultural non-point source pollution in purple arid sloping land. The effects of four treatments on surface runoff and soil nitrogen loss patterns and fluxes in purple arid sloping land were studied by field experiments, including no fertilization (control), conventional fertilization, optimized fertilization, and biochar (fertilizer reduction and biochar application). The results showed that:① Of the fertilization treatments, the total runoff of conventional treatment was the highest at 16133 L·a, and the total runoff of biochar treatment was the lowest at 11893 L·a.

[Response of Nitrogen Loss Flux in Purple Soil Sloping Field to Reduced Fertilizer and Combining Straw].

The purple soil sloping field is considered as the main source of sediment and non-point source pollution in the Three Gorges Reservoir area. To prevent and control the non-point source pollution, it is indispensable to explore the characteristics of nitrogen loss in the overland flow and interflow of purple soil sloping field in Three Gorges Reservoir area. The purple soil sloping runoff plots, located in the Shibaozhai Experimental Station of Chengdu Institute of Chinese Academy of Sciences in Zhongxian County, Chongqing, were studied.

[Effects of Fertilizer Reduction and Application of Organic Fertilizer on Soil Nitrogen and Phosphorus Nutrients and Crop Yield in a Purple Soil Sloping Field].

The reduction in chemical fertilizers combined with organic fertilizers is a national strategy to achieve environmental friendliness and maintain the quality of cultivated land. It is of great significance for the prevention and control of soil pollution and the sustainable development of agriculture. In this study, purple soil and sloping land in the Three Gorges Reservoir area was studied.

[Characteristics of Nitrogen and Phosphorus Output and Loss Flux in the Shipanqiu Watershed, Three Gorges Reservoir Area].

As the source of non-point pollution in the Three Gorges Reservoir Area, small watershed is a key control object in alleviating deterioration of water quality. In the Three Gorges Reservoir Area, the Shipanqiu small watershed with various land-use types was selected as the research object, and the water quantity and quality of the outlet section of the watershed were continuously monitored. We carried out analysis of the small watershed runoff loss and nitrogen and phosphorus pollutants with concentration, analyzed the morphology change characteristics of runoff erosion, calculated the small watershed of pollutant emission flux, and analyzed the nitrogen and phosphorus nutrient loss and main human and natural factors, especially in the Three Gorges Reservoir Area of agriculture where nonpoint source pollution research has important practical significance.

Growth hormone receptor promotes breast cancer progression via the BRAF/MEK/ERK signaling pathway.

Growth hormone receptor (GHR), a member of the class I cytokine receptor family, plays key roles in cancer progression. Recently, GHR has been reported to be associated with breast cancer development, but the molecular mechanism of GHR in this malignancy is not fully understood. To investigate this issue, we stably inhibited GHR in breast cancer cell lines, which were observed to reduce cell proliferation, tumor growth and induction of apoptosis, and arrest the cell-cycle arrest at the G1-S phase transition.

A novel cis antisense RNA AsfD promotes Salmonella enterica serovar Typhi motility and biofilm formation.

Bacterial non-coding RNAs (ncRNAs) can participate in multiple biological processes, including motility, biofilm formation, and virulence. Using high-throughput sequencing and transcriptome analysis of Salmonella enterica serovar Typhi (S. Typhi), we identified a novel antisense RNA located at the opposite strand of the flhDC operon.

Aquaporins and their function in root water transport under salt stress conditions in Eutrema salsugineum.

Eutrema salsugineum is considered as extremophile model species. To gain insights into the root hydraulic conductivity and the role played by aquaporins in E. salsugineum, we investigated the aquaporin family profiles, plant water status and root hydraulic conductivity under standard (salt-free) and salt stress conditions.

[Response of the Soil NO Emission and Ammonia-oxidizing Microorganism Community to the Maize Straw Return with Reducing Fertilizer in Purple Soil].

Crop straw is an important agricultural source, which can replace chemical fertilizers. A field experiment with six different amounts of fertilization combined with maize straw residues was carried out in purple soil, including the control (CK), conventional fertilizing (F), straw return with conventional fertilizing (100FS), straw return with 70% conventional fertilizing (70FS), straw return with 60% conventional fertilizing (60FS), and straw return with 50% regular fertilizing (50FS), to determine the response of the soil NO emission and ammonia-oxidizing microorganism community distribution to straw return with reducing fertilizer. The dynamic characteristics of the NO emission in purple soil were observed using an closed chamber and gas chromatography-based system.

[Effect of Straw Residues in Combination with Reduced Fertilization Rate on Greenhouse Gas Emissions from a Vegetable Field].

Greenhouse gases mainly come from farmland soils. Re-spreading chaff (straw returning) is an effective ecological management in China. Quantitative analysis of straw residues together with reduced fertilization rates can provide a scientific basis for reducing greenhouse gas emissions.

[Effects of Straw and Biochar Addition on Soil Carbon Balance and Ecological Benefits in a Rape-maize Rotation Planting System].

The effects of different straw and biochar applications on the carbon balance of a farmland ecosystem were studied under a rape-maize rotation planting system. The study explored impact of straw and biochar addition on soil carbon sequestration. A field experiment was carried out at the National Monitor Station of Soil Fertility and Fertilizer Efficiency of Purple Soils (Chongqing, China).

[Effects of Straw and Biochar Return in Soil on Soil Aggregate and Carbon Sequestration].

The aim of this work is to understand the effects of straw and biochar return in soil on the content, distribution, stability, and relative contribution rate of organic carbon for soil aggregates, which could be used to better understanding the stability of the soil carbon pool and the protection mechanisms under straw and biochar return. In this study, a field experiment was conducted to study the effects of straw and biochar return on soil aggregates and carbon sequestration characteristics in a rape-maize rotation planting system. Five treatments, including a control (no organic material added, CK), straw (CS), straw and microorganism (CSD), Biochar (BC), half straw and half biochar (CSBC), were used.

Study on the kinetic characteristics of trace harmful gases for a two-person-30-day integrated CELSS test.

A two-person-30-day controlled ecological life support system (CELSS) integrated test was carried out, and more than 30 kinds of trace harmful gases including formaldehyde, benzene, and ammonia were measured and analyzed dynamically. The results showed that the kinds and quantities of the trace harmful gases presented a continuously fluctuating state during the experimental period, but none of them exceed the spacecraft maximum allowable concentration (SMAC). The results of the Pre-Test (with two persons without plants for 3 days) and the Test (with two persons and four kinds of plants for 30 days) showed that there are some notable differences for the compositions of the trace harmful gases; the volatile organic compounds (VOCs) such as toluene, hexane, and acetamide were searched out in the Pre-Test, but were not found in the Test.