Publications by authors named "Guoxia Shi"
Article Synopsis
- * In experiments with mouse carotid arteries, it was found that chronic oscillatory flow leads to hyperplastic lesions, reduced endothelial integrity, and increased smooth muscle cell-like characteristics, all indicative of superficial erosion risks.
- * The research suggests that oscillatory flow activates EndMT in a way that depends on DNA methyltransferases, and inhibiting this process could offer new prevention strategies for superficial erosions.
During myocardial ischaemia‒reperfusion injury (MIRI), the accumulation of damaged mitochondria could pose serious threats to the heart. The migrasomes, newly discovered mitocytosis-mediating organelles, selectively remove damaged mitochondria to provide mitochondrial quality control. Here, we utilised low-intensity pulsed ultrasound (LIPUS) on MIRI mice model and demonstrated that LIPUS reduced the infarcted area and improved cardiac dysfunction.
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