Publications by authors named "Guowei Qiu"

Eucalyptus roots form symbiotic relationships with arbuscular mycorrhizal (AM) fungi in soil to enhance adaptation in challenging environments. However, the evolution of the AM fungal community along a chronosequence of eucalypt plantations and its relationship with soil properties remain unclear. In this study, we evaluated the tree growth, soil properties, and root AM fungal colonization of W.

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Iron and phosphorus are essential nutrients that exist at low concentrations in surface waters and may be co-limiting resources for phytoplankton growth. Here, we show that phosphorus deficiency increases the growth of iron-limited cyanobacteria (Synechocystis sp. PCC 6803) through a PhoB-mediated regulatory network.

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Hemisphere functional lateralization is a prominent feature of the human brain. However, it is not known whether hemispheric lateralization features are altered in end-stage knee osteoarthritis (esKOA). In this study, we performed resting-state functional magnetic imaging on 46 esKOA patients and 31 healthy controls (HCs) and compared with the global and inter-hemisphere network to clarify the hemispheric functional network lateralization characteristics of patients.

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Article Synopsis
  • Fibroblast-like synoviocytes (FLSs) play a key role in the inflammation and joint damage associated with rheumatoid arthritis (RA), especially during relapse phases, but their specific regulatory mechanisms remain unclear.
  • Researchers utilized advanced sequencing techniques to analyze synovial tissue samples from RA patients in both relapse and remission states, identifying significant differences in FLS subsets and their activity levels.
  • The study found that the fibroblast growth factor (FGF) pathway, particularly through FGF10, is highly activated in relapse RA, highlighting its potential as a target for new treatments, demonstrated by successful inhibition in a rat model.
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Rheumatoid arthritis (RA) joint inflammation severely affects joint function and quality of life in patients and leads to joint deformities and limb disability. The non-steroidal anti-inflammatory drugs used in the treatment of RA do not fully control the progression of joint inflammation and bone destruction and have notable adverse reactions. Traditional Chinese medicine formula JuanBiQiangGu Granules (JBQG) are commonly used for the treatment of RA inflammation and delay of bone destruction, but has not been evaluated through high-quality clinical studies.

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Objective: To evaluate the effectiveness of Tuina in relieving the pain, negative emotions, and disability of patients with knee osteoarthritis (KOA).

Design: Single-center, parallel, randomized controlled trial.

Setting: Shanghai Guanghua Integrated Chinese and Western Medicine Hospital, Shanghai, China.

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The mechanisms underlying osteoarthritis (OA) have recently been hypothesized to involve a dysfunctional immune system. In this study, we collected synovium, synovial fluid (SF), and peripheral blood from 21 patients. Mononuclear cells were characterized using FCM.

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Iron is an essential micronutrient for the ecologically important photoautotrophic cyanobacteria which are found across diverse aquatic environments. Low concentrations and poor bioavailability of certain iron species exert a strong control on cyanobacterial growth, affecting ecosystem structure and biogeochemical cycling. Here, we review the iron-acquisition pathways cyanobacteria utilize for overcoming these challenges.

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Cyanobacteria are globally important primary producers and nitrogen fixers. They are frequently limited by iron bioavailability in natural environments that often fluctuate due to rapid consumption and irregular influx of external Fe. Here we identify a succession of physiological changes in Synechocystis sp.

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Cyanobacteria are globally important primary producers and nitrogen fixers with high iron demands. Low ambient dissolved iron concentrations in many aquatic environments mean that these organisms must maintain sufficient and selective transport of iron into the cell. However, the nature of iron transport pathways through the cyanobacterial outer membrane remains obscure.

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Background: Total knee arthroplasty (TKA) is a gold standard for patients with terminal term gonarthrosis for reducing pain, correcting deformities, and regaining stability. However, post-TKA muscle strength recovery is often difficult. Although electroacupuncture (EA) enhances lower extremity muscle strength of the lower extremity, there is limited evidence regarding its effect on lower extremity muscle strength in post-TKA patients.

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Article Synopsis
  • - Cyanobacteria play a crucial role in nutrient cycling globally, particularly concerning their high need for iron (Fe), which is usually found in very low levels in aquatic environments.
  • - Researchers identified specific proteins and transporters that help these organisms acquire Fe, revealing that while some transporters are vital for taking up iron from organic sources, they still have alternative methods for acquiring inorganic Fe.
  • - Mutations in certain genes related to Fe uptake pathways showed varying effects on the ability of cyanobacteria to survive and acquire iron, highlighting their evolutionary adaptations to low-Fe conditions in aquatic ecosystems.
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Cyanobacteria are globally important primary producers and abundant in many iron-limited aquatic environments. The ways in which they take up iron are largely unknown, but reduction of Fe is an important step in the process. Here we report a special iron permease in Synechocystis, cFTR1, that is required for Fe uptake following Fe re-oxidation.

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