A visual knowledge map analysis of mine fire research based on CiteSpace.

Mine fire has always been a serious disaster in coal industry; many academic achievements have poured out in the past two decades for solving this problem. In this study, visual analysis was conducted to grasp the hotspots and development trend of mine fire research. Papers that published in 1999-2020 were retrieved as the data basis from Web of Science, and CiteSpace was used to carry out knowledge map analysis.

Effect of Virus Inactivation by Heating on Routine Clinical Laboratory Indicators in Serum.

Background: Highly infectious viruses such as SARS-CoV-2, MERS-CoV, and Ebola virus represent a threat to clinical laboratory workers. We aimed to investigate how virus inactivation by heating at 60°C for 1 hour affects routine clinical laboratory indicators.

Methods: Each collected serum sample was separated into two aliquots, and various indicators were measured in first aliquot after inactivation by heating at 60°C for 1 hour and in the second after room-temperature incubation for 1 hour.

Influencing factors of coronary artery stenosis in patients with stable coronary heart disease and a correlation analysis.

Objective: To explore the relationship of the size and concentration of low density lipoprotein (LDL) particles and high density lipoprotein (HDL) particles and the coronary stenotic degree of stable coronary artery disease.

Methods: Altogether 62 patients with coronary disease confirmed by coronary angiography treated in our hospital from March 2019 to March 2020 were selected as the observation group, and 62 healthy persons in the same period were chosen as the control group. The particle size of LDL and HDL protein complexes were measured and we then calculated the concentration ratio to explore the relationship between the two types of lipoprotein particles and the degree of coronary artery disease.

LncRNA PART1 alleviated myocardial ischemia/reperfusion injury via suppressing miR-503-5p/BIRC5 mediated mitochondrial apoptosis.

Background: Long non-coding RNA (lncRNA) is crucial for heart development and for adult heart structural maintenance and function. Herein, we performed a study to explore the effect of lncRNA PART1 on myocardial ischemia-reperfusion (I/R) injury by targeting BIRC5 through miR-503-5p pathway.

Methods: I/R model was created in vivo and vitro.

Anti-apoptotic Effect of MiR-223-3p Suppressing PIK3C2A in Cardiomyocytes from Myocardial Infarction Rat Through Regulating PI3K/Akt Signaling Pathway.

We aimed to explore the regulatory mechanism of the axis of miR-223-3p-PIK3C2A-PI3K/Akt on cardiomyocyte apoptosis in rats with myocardial infarction. Thirty 8-week-old healthy male SD rats were used for establishing the sham group and the model group, with HE staining, TUNEL staining, and TTC staining performed. After the identification of the targeting relationship between PIK3C2A and miR-223-3p, experimental rats were randomly divided into seven groups by plasmid transfection, including the Blank group, negative control (NC) group, miR-223-3p mimic group, miR-223-3p inhibitor group, siRNA-PIK3C2A group, oe-PIK3C2A group, and miR-223-3p inhibitor + oe-PIK3C2A group.

Conformationally Restricted α, α Directly Linked BisBODIPYs as Highly Fluorescent Near-Infrared Absorbing Dyes.

A new family of α, α directly linked bisBODIPYs was developed through a MoCl-mediated intramolecular oxidative reaction. Due to the coplanar structure of the two conformationally locked BODIPY units, these bisBODIPYs showed well-extended conjugations and gave strong near-infrared absorptions and emissions with maxima around 760 and 780 nm, respectively, with high fluorescence quantum yields of ≤0.84.

Effect of atorvastatin treatment on circulating adiponectin: a meta-analysis of randomized controlled trials.

Background: Influences of atorvastatin on atherosclerosis and glycemic metabolism may be related to its potential impact on circulating adiponectin, an adipocyte that exerts anti-inflammatory, ant-atherosclerotic, and anti-oxidative effects. However, results of previous randomized controlled trials (RCTs) were not consistent. We performed a meta-analysis of RCTs to systematic evaluate the influence of atorvastatin on circulating adiponectin.

Protective effect of diethylcarbamazine inhibits NF-κB activation in isoproterenol-induced acute myocardial infarction rat model through the PARP pathway.

The present study investigated the protective effect of diethylcarbamazine in inhibiting nuclear factor (NF)-κB activation in isoproterenol‑induced acute myocardial infarction (AMI) rats through the poly ADP ribose polymerase (PARP) pathway. Male albino Wistar rats were injected subcutaneously with isoproterenol (100 mg/kg/day) for 2 days to induce an AMI model. Diethylcarbamazine (50 mg/kg) was administered by gavage for 12 days prior to the isoproterenol-induced AMI.