Boosting Reactive Oxygen Species Generation with a Dual-Catalytic Nanomedicine for Enhanced Tumor Nanocatalytic Therapy.

Generating lethal reactive oxygen species (ROS) within tumors by nanocatalytic medicines is an advanced strategy for tumor-specific therapy in recent years. Nevertheless, the low yield of ROS restrains its therapeutic efficiency. Herein, a dual-catalytic nanomedicine based on tumor microenvironment (TME)-responsive liposomal nanosystem co-delivering CuO and dihydroartemisinin (DHA) (LIPSe@CuO&DHA) is developed to boost ROS generation against tumor.

Graphene oxide quantum dots attached on wood-derived nanocellulose to fabricate a highly sensitive humidity sensor.

Herein, cellulose nanofibril (CNF) with various carboxyl amounts were prepared via regulating its oxidation degree using TEMPO oxidation. The CNF dispersion was dropped onto the interdigital electrode to be capacitive humidity sensor by the subsequent vacuum freeze-drying. Pure CNF-7 (NaClO content of 7 mmol/g) humidity sensor involves in orderly porous structure, which displays better performance than other CNFs for its moderate carboxyl content and dimension.

Performance of the highly sensitive humidity sensor constructed with nanofibrillated cellulose/graphene oxide/polydimethylsiloxane aerogel freeze drying.

A kind of capacitive humidity sensor with high sensitivity constructed with nanofibrillated cellulose (NFC), graphene oxide (GO) and polydimethylsiloxane (PDMS) is presented in this work, a simple ultrasonic dispersion and freeze drying technology. The NFC and GO with a strong adsorption for water molecules were used as a substrate for the promotion of capacitive response of the humidity sensor. Moreover, anhydrous ethanol was added to inhibit the generation of big cracks in the humidity sensor in the freeze drying process, so as to obtain a regular network porous structure, then providing a great deal of conduction channels and active sites for molecular water.