[Simultaneous determination of residues of three fluoroquinolones in chicken using high performance liquid chromatography with post-column derivatization and terbium sensitized fluorescence].

A method of high performance liquid chromatography with post-column derivatization and terbium sensitized fluorescence for simultaneous determination of residues of ciprofloxacin, norfloxacin and enrofloxacin in chicken was established, based on the effect that Tb3+ can sensibilize fluorescence of fluoroquinolones. Under the optimal chromatographic condition, three fluoroquinolones were separated on a C18 column with 0.05 mol/L acetic acid/acetate buffer-acetonitrile (89:11, v/v) as the mobile phase, and at a flow rate of 0.