Publications by authors named "Guoou Xie"
Article Synopsis
- No prior studies have explored the impact of Omicron on male sexual function and semen quality, prompting this research to analyze changes since the pandemic began.
- A total of 1540 questionnaires were collected and analyzed, revealing that erectile dysfunction significantly increased during the acute phase post-infection, although ejaculatory function remained stable.
- Semen analysis of 247 males showed notable differences in semen concentration, activity, and sperm movement post-infection, suggesting that Omicron may negatively influence male sexual health due to factors like body temperature and anxiety.
Bladder cancer (BLCA), ranking as the tenth most prevalent malignancy globally, imposes a substantial public health and socio-economic challenge. Despite ongoing efforts by urologists to identify novel molecular subtypes and treatment paradigms, the intrinsic heterogeneity of BLCA continues to obstruct the efficacy of current diagnostic and therapeutic evaluations, leaving a gap in the comprehensive management of BLCA. This necessitates an in-depth investigation into the BLCA tumor microenvironment (TME) to identify pivotal molecules like MFAP3L.
View Article and Find Full Text PDFBackground: The long non-coding RNA (lncRNA) AGAP2-AS1 was implicated in tumorigenesis, yet with unclear mechanism in the development of Bladder Cancer (BCa).
Methods: We collected the clinicopathological features and tissue samples of 45 patients with BCa in Xiangya Hospital. Expressions of AGAP2-AS1 and LRG1 were detected by RT-qPCR in BCa tissues and normal tissues as well as in BCa cells.