Publications by authors named "Guoming Du"

Estimating human joint angles is a crucial task in motion analysis, gesture recognition, and motion intention prediction. This paper presents a novel model-based approach for generating reliable and accurate human joint angle estimation using a dual-branch network. The proposed network leverages combined features derived from encoded sEMG signals and RGB-D image data.

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  • The study focuses on how the human gut microbiota processes dietary carbohydrates decorated with ferulic acid (FA), which offers health benefits.
  • Researchers presented the crystal structure of a decameric feruloyl esterase (Fae) in complex with methyl ferulate (MFA), illustrating how MFA binds in a noncatalytic pocket that influences enzyme activity.
  • Additionally, experiments using molecular docking and quantum mechanics revealed that this adjacent pocket impacts substrate binding and negatively regulates Fae's activity, potentially affecting the metabolism of FA-conjugated polysaccharides in the gut.
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Comparing with cities, rural communities especially those declining rural communities have become vulnerable to natural disasters owing to their backward socioeconomic conditions. Taking Xun County of China's Henan Province as the study area, the paper aims to evaluate rural community resilience to flood by unveiling the connection between individuals' cognition, follow-up actions and the community resilience. Research results show that: (1) The logic chain exists as individual's cognition to disaster leads to their constructive actions to cope with disaster, which contribute to community resilience.

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  • - The paper focuses on understanding how agriculture's vulnerability to drought and floods has changed globally from 2003 to 2019, emphasizing the need for climate resilience in farming.
  • - Research findings indicate that overall agricultural vulnerability is low worldwide due to reduced exposure to disasters and improved adaptability, although certain regions, like northern U.S., northeastern China, and the Russia-Kazakhstan border are identified as particularly at risk.
  • - The study highlights that mismatched precipitation patterns primarily drive the occurrence of floods and droughts, and suggests that increased adaptability can help mitigate the negative impacts of these climate-related disasters.
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Rheumatoid arthritis (RA) is caused by inflammatory response of joints with cartilage and damage of synovium and bone erosion. In our previous studies, it has showed that irradiation of 630 nm LED reduce inflammation of synovial fibroblasts and cartilage and bone destruction in RA. However, the key genes and mechanism in ameliorating RA by irradiation of 630 nm LED remains unknown.

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Glycosylation is an important post-translational modification of proteins, contributing to protein function, stability and subcellular localization. Fungal immunomodulatory proteins (FIPs) are a group of small proteins with notable immunomodulatory activity, some of which are glycoproteins. In this study, the impact of glycosylation on the bioactivity and biochemical characteristics of FIP-nha (from ) is described.

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  • Oligomeric feruloyl esterase (FAE) shows great potential for industrial use due to its stability and adjustable activity, but the link between its structure and catalytic function hasn't been fully explored.
  • Researchers discovered a new cold-adapted FAE from Bacteroides thetaiotaomicron (BtFae), which has a unique decameric barrel-like structure among esterases.
  • The study found that breaking up this structure significantly decreases the enzyme’s activity and stability, hindering its ability to release ferulic acid from wheat sources, revealing crucial insights for future protein engineering of FAEs to enhance their industrial applications.
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Land degradation in black soil regions has a significant effect on belowground systems, and Collembolans can adequately indicate environmental changes in the soil. However, there is currently a knowledge gap in the literature regarding the responses of soil Collembolans to land degradation. In order to better understand this issue, in this study, a total of 180 soil Collembolan samples were collected from four habitats with varying degrees of land degradation in the Songnen Plain, namely a no land-degradation habitat (NLD), light land-degradation habitat (LLD), moderate land-degradation habitat (MLD) and severe land-degradation habitat (SLD).

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Glutamate decarboxylase catalyzes the conversion of glutamate to γ-aminobutyric acid, which plays a vital role in the gut-brain axis. Herein, a novel glutamate decarboxylase from Bacteroides thetaiotaomicron (BTGAD) was heterologously expressed. BTGAD possessed high catalytic efficiency at 60℃ and pH 3.

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A better understanding of the dynamic variation in the ecosystem service value (ESV) under land use/cover change (LUCC) is conductive to improving ecosystem services and environmental protection. The present study took Landsat TM/ETM remote sensing images and socio-economic statistic data as data sources and extracted land-use data using RS and GIS technology at 5-year intervals from 1990 to 2020. Then, we interpreted the spatio-temporal characteristics of LUCC and analyzed ESV changes using the value equivalence method in the black soil region of northeastern China (BSRNC).

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Fungal immunomodulatory proteins (FIPs) have been investigated for their use as potential natural derived anti-tumor molecules. However, the stability of FIPs is critical for their preparation and storage. In this study, the correlation between thermal stability and protein structural features of rFIP-nha, with significant anti-tumor activity, has been evaluated.

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Different cropping patterns have their own economic and ecological significance. Developing cropping patterns suitable for local conditions is needed to protect and make good use of black soils. At present, the cropping patterns and their spatial characteristics in the black soil region of Northeast China is poorly understood.

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  • - Cropland shifts from high-quality areas in southern China to marginal lands in the northeast and northwest (1990-2015) were driven by urbanization and aimed at maintaining food security, resulting in significant land use changes.
  • - This expansion into ecologically sensitive zones led to negative environmental impacts, including increased wind erosion, water usage, fertilizer application, and reduced natural habitats.
  • - Future policies promoting more reclamation of marginal lands could worsen environmental issues and threaten food security, suggesting a need to limit such practices and focus on increasing crop yields for sustainable food production.
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Feruloyl esterase is an indispensable biocatalyst in food processing, pesticide and pharmaceutical industries, catalyzing the cleavage of the ester bond cross-linked between the polysaccharide side chain of hemicellulose and ferulic acid in plant cell walls. LP_0796 from Lactobacillus plantarum was identified as a feruloyl esterase that may have potential applications in the food industry, but the lack of the substrate recognition and catalytic mechanisms limits its application. Here, LP_0796 showed the highest activity towards methyl caffeate at pH 6.

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Retinoic acid-inducible gene I-like receptors (RLRs) play an essential role in human innate immune, which may influence the spontaneous clearance of hepatitis B virus (HBV) infection. We aimed to investigate whether the SNPs in RLR family were associated with HBV spontaneous clearance. The current study included 82 participants with spontaneous clearance, 601 asymptomatic hepatitis B surface antigen (HBsAg) carriers, and 168 participants with chronic hepatitis B (CHB).

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Northeast China is the leading grain production region in China where one-fifth of the national grain is produced; however, consistent and reliable crop maps are still unavailable, impeding crop management decisions for regional and national food security. Here, we produced annual 10-m crop maps of the major crops (maize, soybean, and rice) in Northeast China from 2017 to 2019, by using (1) a hierarchical mapping strategy (cropland mapping followed by crop classification), (2) agro-climate zone-specific random forest classifiers, (3) interpolated and smoothed 10-day Sentinel-2 time series data, and (4) optimized features from spectral, temporal, and texture characteristics of the land surface. The resultant maps have high overall accuracies (OA) spanning from 0.

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Alcoholic liver disease (ALD) has become one of the leading causes of death in the world. Berbamine (BM), a natural product mainly derived from Berberis vulgaris L, possesses multiple bioactivities as a traditional medicine. However, the protective effect of BM on ALD remains unknown.

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The recent acute evolution of cropland structure in Cold China could lead to rapid rice paddy expansion, potentially altering land-surface thermal processes and influencing climate. To address the issue, this study investigated the changes in cropland type, land-surface temperature (LST) and heat fluxes in the agricultural region of Cold China during 2000-2015 based on time-series of land-use data and MODIS LST product, using the split-window algorithms (SWA) model and the pixel component arranging and component algorithm (PCACA). The investigation revealed large-scale land transformation from rain-fed farmland to paddy field in Cold China during 2000-2015.

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China is the largest rice producer and consumer in the world. Accurate estimations of paddy rice planting area and rice grain production is important for feeding the increasing population in China. However, Southern China had substantial losses in paddy rice area over the last three decades in those regions where paddy rice has traditionally been produced.

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  • Drastic expansion of rice paddies and loss of upland crops in high latitude China raises concerns for national food security, with varying land use patterns in state and private farms.
  • A methodology used in the study had over 90% accuracy in determining cropping patterns, revealing that between 2000-2015, rice paddies increased significantly while upland crops decreased.
  • State farms saw a faster expansion of rice paddies compared to private farms, and the conversion of upland crops to rice paddies contributed notably (10.69%) to the net increase in grain production, highlighting its importance for food security and sustainability.
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  • * By using time series images from MODIS and Landsat, along with a pixel- and phenology-based algorithm, researchers successfully mapped paddy rice planting areas in China with high accuracy.
  • * The resulting maps had an overall accuracy of 97.3% and aligned well with official statistics, showcasing the effectiveness of combining high-resolution imagery and advanced algorithms for agricultural mapping.
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  • Agriculture in North China is changing due to global climate change, particularly shifting from upland to paddy cropland, altering landscape patterns significantly.
  • A study compared land use maps from Fujin City in 2000 and 2013, revealing that paddy cropland increased dramatically from 6.7% to over 54% of total cropland.
  • Analysis showed different characteristics between reclamation and common agricultural areas, with reclamation areas having a much higher paddy field ratio as well as changes in patch density and connectivity in cropland types.
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  • * The study aims to develop an urban flood risk warning method, as existing approaches are not mature enough for rapidly urbanizing cities in China.
  • * The proposed flood forecasting model includes five modules that assess drainage systems, precipitation, runoff production, and routing to produce an urban flood inundation index for effective flood risk warning.
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