UV-B irradiation promotes anthocyanin biosynthesis in the leaves of .

Anthocyanins are the most valuable pigments in (). Although ultraviolet-B (UV-B) irradiation is a key environmental factor influencing anthocyanin biosynthesis in , the deep molecular mechanism remains unclear. Herein, we examined the changes in the total anthocyanin content and transcriptomic characteristics of leaves following UV-B irradiation treatment.

Assembly and Comparative Analysis of the Complete Mitochondrial Genome of (Asteraceae).

is a perennial herb used in traditional Chinese medicine and is effective against rheumatoid arthritis. In this study, we sequenced the complete mitochondrial (mt) genome of (GenBank accession number: ON584565.1).

Identifying autophagy-related genes as potential targets for immunotherapy in tuberculosis.

Purpose: Identifying of host-directed targets and molecular markers of immune response for tuberculosis (TB) immunotherapy is urgent and meaningful. Previous studies have demonstrated an important role of autophagy in the course and pathophysiology of TB and is associated with the efficacy of TB treatment. However, its role in TB immunotherapy is still incomplete.

Mining biomarkers from routine laboratory tests in clinical records associated with air pollution health risk assessment.

Clinical laboratory in hospital can produce amounts of health data every day. The purpose of this study was to mine biomarkers from clinical laboratory big data associated with the air pollution health risk assessment using clinical records. 13, 045, 629 clinical records of all 27 routine laboratory tests in Changsha Central Hospital, including ALB, TBIL, ALT, DBIL, AST, TP, UREA, UA, CREA, GLU, CK, CKMB, LDL-C, TG, TC, HDL-C, CRP, WBC, Na, K, Ca, Cl, APTT, PT, FIB, TT, RBC and those daily air pollutants concentration monitoring data of Changsha, including PM, PM, SO, NO, CO, and O from 2014 to 2016, were retrieved.

Characterization and phylogenetic analysis of the complete chloroplast genome of (Liliaceae).

The chloroplast genome and evolutionary relationship analysis of could provide fundamental genetic reference for its molecular breeding and biological research. The complete chloroplast genome of was sequenced and reported here. The genome was 152,050 bp in length, containing a pair of inverted repeated regions (26,330 bp) which were separated by a large single copy region of 82,184 bp, and a small single copy region of 17,206 bp.

Complete chloroplast genome of (Liliaceae).

The complete chloroplast genome of was sequenced and reported here. The circular genome of is 152,062 bp in length and contains 133 functional genes consisting of 87 coding sequences, 38 tRNA genes, and 8 rRNA genes. With 1 species from Smilacaceae and 1 species from Alstroemeriaceae as outgroup, phylogenetic relationships of 8 Liliaceae species based on their chloroplast genomes indicated that is closest to .

Emergence of nontuberculous mycobacteria infections during bedaquiline-containing regimens in multidrug-resistant tuberculosis patients.

Objectives: The World Health Organization recommends the use of bedaquiline (BDQ) to formulate efficacious combination regimens against multidrug-resistant tuberculosis (MDR-TB). This study reports, for the first time, a case series of MDR-TB patients treated with BDQ who experienced sputum culture reconversion due to emergence of nontuberculous mycobacteria (NTM) infections.

Methods: A multicentre case series was established, including patients who started treatment for laboratory-confirmed MDR-TB between January 1, 2018 and March 31, 2020.

Association between fine particle exposure and common test items in clinical laboratory: A time-series analysis in Changsha, China.

Most studies on the health effects of PM (fine particulate matter with diameter smaller than 2.5 μm) use indirect indicators, such as mortality and number of hospital visits. Recent research shows that biomarkers can also be used to evaluate the health effects of PM; however, these biomarkers are not very common.

RNA-binding protein HuR regulates hsa-let-7c expression by its RNA recognition motif.

MicroRNAs (miRNAs) are small noncoding RNAs that control diverse cellular and developmental events through repression of large sets of target mRNAs. miRNAs expressions were mainly regulated at two levels: transcriptional and post-transcriptional. Transcriptional regulation of miRNA-encoding genes produce specific expression patterns of individual miRNA.