Synopsis of recent research by authors named "Guolin Tan"
- Guolin Tan's recent research primarily focuses on the mechanisms of cancer progression and immune responses, particularly in head and neck squamous cell carcinoma (HNSCC) and allergic rhinitis. He has identified a novel subtype of cancer-associated fibroblasts (SFRP2_CAFs) that are linked to adverse outcomes in HNSCC patients.
- His studies utilize advanced methodologies such as single-cell analysis and Mendelian randomization to investigate causal relationships and therapeutic potentials in conditions like allergic rhinitis and chronic rhinosinusitis, emphasizing the significance of eosinophils and immune signaling pathways.
- Tan has also explored the immune microenvironment and inflammatory markers in relation to cancer prognosis, highlighting the predictive value of various blood cell ratios for survival outcomes in advanced nasopharyngeal carcinoma.