Aberrantly Expressed lncRNA LINC00847 May Serve as a Promising Prognostic Factor for Thyroid Cancer.

Thyroid cancer is a tumor that occurs in the head and neck, which originates from the thyroid follicular epithelial cells. The current research is discussed and elaborated from the perspective of molecular prognostic biomarkers to gain a deeper understanding of the molecular mechanism of thyroid cancer and to provide more effective treatment and prognostic methods for patients. Thyroid cancer patients were explored from histological, cellular and clinical levels.

Identification of a novel ceRNA network related to prognosis and immunity in HNSCC based on integrated bioinformatic investigation.

Head and neck squamous cell carcinoma (HNSCC) is characterized by an immunosuppression environment and necessitates the development of new immunotherapy response predictors. The study aimed to build a prognosis-related competing endogenous RNA (ceRNA) network based on immune-related genes (IRGs) and analyze its immunological signatures. Differentially expressed IRGs were identified by bioinformatics analysis with Gene Expression Omnibus (GEO), The Cancer Genome Atlas (TCGA) and ImmPort databases.