Regional scale terrace mapping in fragmented mountainous areas using multi-source remote sensing data and sample purification strategy.

As a stepped cross section of farmland built along the contour lines, terrace is widely distributed on hill-slopes. It changes the original surface slope and runoff coefficient, reduces soil nutrient loss, and has become the most important soil erosion control measure in China. Accurate terrace mapping at regional scale is crucial for soil conservation, agriculture sustainability and ecological planning.

Corrigendum: Circadian rhythm protein Bmal1 modulates cartilage gene expression in temporomandibular joint osteoarthritis via the MAPK/ERK pathway.

[This corrects the article DOI: 10.3389/fphar.2020.

PAP Polypeptide Promotes Osteogenesis in Jaw Bone Defect Repair by Inhibiting Inflammatory Reactions.

Jaw defects are common in oral and maxillofacial diseases and require surgical repair in extreme cases. Given the limitations in availability and efficacy of autologous bone grafts or allografts, great effort has been made in finding suitable, biocompatible, and effective artificial bone materials. Considering the key role of inflammation in bone resorption, we sought to identify a polypeptide with anti-inflammatory and bone-promoting effects.

The Construction of Ecological Security Patterns in Coastal Areas Based on Landscape Ecological Risk Assessment-A Case Study of Jiaodong Peninsula, China.

Increasing land utilization, population aggregation and strong land-sea interaction make coastal areas an ecologically fragile environment. The construction of an ecological security pattern is important for maintaining the function of the coastal ecosystem. This paper takes Jiaodong Peninsula in China, a hilly coastal area, as an example for evaluating landscape ecological risk within a comprehensive framework of "nature-neighborhood-landscape", based on spatial principal component analysis, and it constructs the ecological security pattern based on the minimum cumulative resistance model (MCR).

Circadian Rhythm Protein Bmal1 Modulates Cartilage Gene Expression in Temporomandibular Joint Osteoarthritis the MAPK/ERK Pathway.

The purpose of this study was to elucidate the role of the circadian gene Bmal1 in human cartilage and its crosstalk with the MAPK/ERK signaling pathway in temporomandibular joint osteoarthritis (TMJ-OA). We verified the periodical variation of the circadian gene Bmal1 and then established a modified multiple platform method (MMPM) to induce circadian rhythm disturbance leading to TMJ-OA. IL-6, p-ERK, and Bmal1 mRNA and protein expression levels were assessed by real-time RT-PCR and immunohistochemistry.

Estrogen-Related Receptor γ Induces Angiogenesis and Extracellular Matrix Degradation of Temporomandibular Joint Osteoarthritis in Rats.

The main causes of cartilage destruction during temporomandibular joint osteoarthritis (TMJOA) are extracellular matrix degradation and angiogenesis, accompanied by an increased level of matrix-degrading enzymes and proangiogenic factors. Interleukin 6 and extracellular signal-regulated kinase (ERK) signaling pathways may play a critical role in these two processes simultaneously, but researchers have not clearly determined the mechanism. We hypothesized that estrogen-related receptor γ (ERRγ) is involved in both cartilage degeneration and angiogenesis in TMJOA.

[Expression and clinical significance of p53 and autophagy-related gene Beclin1 in salivary pleomorphic adenoma and carcinoma in pleomorphic adenoma].

Purpose: To investigate the expression of p53 and Beclin1 in salivary pleomorphic adenoma (PA) and its clinical significance.

Methods: The expression of p53 and Beclin1 were assessed by immunohistochemistry in 108 cases of PA and 20 cases of carcinoma in pleomorphic adenoma(CIPA). The results were used to analyze the relationship between gene expressions and the development of PA as well as the clinical pathological features.