Umbilical cord blood (UCB) showcases substantial roles in hematopoietic stem cells (HSCs) transplantation and regenerative medicine. UCB is usually cryopreserved for years before use. Whether and how cryopreservation affects its function remain unclear.
View Article and Find Full Text PDFDoxycycline hydrochloride (DOX) is a widely used broad-spectrum antibiotic that is challenging to degrade, leading to a series of environmental issues. In this study, a bimetallic oxide catalyst was synthesized through hydrothermal calcination followed by annealing. The catalytic carbon cloth anode was fabricated by bonding materials directly onto carbon cloth.
View Article and Find Full Text PDFStat Methods Med Res
February 2025
Multivariate control charts have found wide application in healthcare, yet they primarily cater to continuous or categorical variables. However, the emergence of mixed-type data has sparked interest in adapting traditional control charts to handle such complexity. Unfortunately, existing methods often struggle to effectively manage this complexity, particularly in scenarios with limited historical in-control data.
View Article and Find Full Text PDFStem Cell Res Ther
February 2025
Background: Non-healing pressure ulcers impose heavy burdens on patients and clinicians. Cord blood mononuclear cells (CB-MNCs) are a novel type of tissue repair seed cells. However, their clinical application is restricted by low retention and survival rates post-transplantation.
View Article and Find Full Text PDFWith the increasing demand for magnesium (Mg) alloys with high strength and good ductility, this study explores high-pressure die-cast (HPDC) Mg-6Al-2RE (AE62), Mg-8Al-2RE (AE82) and Mg-8Al-2RE-0.2Ca (AEX820) alloys (wt. %).
View Article and Find Full Text PDFSensors (Basel)
December 2024
Fiber Bragg gratings (FBGs) are widely used in stress and temperature sensing due to their small size, light weight, high resistance to high temperatures, corrosion, electromagnetic interference, and low cost. In recent years, various structural enhancements and sensitization to FBGs have been explored to improve the performance of ocean temperature and depth sensors, thereby enhancing the accuracy and detection range of ocean temperature and depth data. This paper reviews advancements in temperature, pressure, and dual-parameter enhancement techniques for FBG-based sensors.
View Article and Find Full Text PDFWe observed tunable characteristics of optical frequency combs (OFCs) generated from InGaAs/GaAs double quantum wells (DQWs) asymmetric waveguide two-section mode-locked lasers (TS-MLLs). This involves an asymmetric waveguide mode-locked semiconductor laser (AWML-SL) operating at a center wavelength of net modal gain of approximately 1.06 µm, which indicates a stable pulse shape, with the power-current(P-I) characteristic curve revealing a small difference between forward and reverse drive currents in the gain region.
View Article and Find Full Text PDFPolymers (Basel)
September 2024
Micromachines (Basel)
August 2024
In this paper, an intelligent blind guide system based on 2D LiDAR and RGB-D camera sensing is proposed, and the system is mounted on a smart cane. The intelligent guide system relies on 2D LiDAR, an RGB-D camera, IMU, GPS, Jetson nano B01, STM32, and other hardware. The main advantage of the intelligent guide system proposed by us is that the distance between the smart cane and obstacles can be measured by 2D LiDAR based on the cartographer algorithm, thus achieving simultaneous localization and mapping (SLAM).
View Article and Find Full Text PDFHistone chaperone FACT (facilitates chromatin transcription) is well known to promote chromatin recovery during transcription. However, the mechanism how FACT regulates genome-wide chromatin accessibility and transcription factor binding has not been fully elucidated. Through loss-of-function studies, we show here that FACT component Ssrp1 is required for DNA replication and DNA damage repair and is also essential for progression of cell phase transition and cell proliferation in mouse embryonic fibroblast cells.
View Article and Find Full Text PDFSichuan Da Xue Xue Bao Yi Xue Ban
September 2023
As one of the main types of structural variation in the human genome, copy number variation (CNV) plays an important role in the occurrence and development of human cancers. Next-generation sequencing (NGS) technology can provide base-level resolution, which provides favorable conditions for the accurate detection of CNVs. However, it is still a very challenging task to accurately detect CNVs from cancer samples with different purity and low sequencing coverage.
View Article and Find Full Text PDFMicromachines (Basel)
August 2023