Tumor-derived exosomal microRNA-15b-5p augments laryngeal cancer by targeting TXNIP.

Tumor-derived exosomes (EXO) are information carriers of microRNA (miR) in cancer development. Here, we explored the synergism of tumor-derived EXO and miR-15b-5p in laryngeal cancer (LCa). miR-15b-5p and thioredoxin-interacting protein (TXNIP) levels were firstly measured in clinical LCa tissues.

Knockdown of Circular RNA hsa_circ_PVT1 Inhibited Laryngeal Cancer Progression via Preventing wnt4/β-Catenin Signaling Pathway Activation.

Aim: To explore the function and mechanism of circular has_circ_PVT1 on laryngeal cancer (LC).

Methods: Microarray chip was performed to screen the differential expression of circRNA. Western blot and qRT-PCR was employed to detect the protein and mRNA level.

Correction to: Two different therapies for the middle turbinate during endoscopic sinus surgery for chronic rhinosinusitis.

In the original publication of the article, Fig. 1a was missing and caption of Fig. 1a was published as caption of Fig.

Two different therapies for the middle turbinate during endoscopic sinus surgery for chronic rhinosinusitis.

Background: The population of patients with chronic rhinosinusitis (CRS) has greatly increased. When medical treatment fails, endoscopic sinus surgery (ESS) is considered. In the present study, the value of two different therapies for the middle turbinate to optimize surgical outcomes was observed.

The Prognostic Significance of Lymph Node Ratio and Log Odds Ratio in Laryngeal Squamous Cell Carcinoma.

Objective: To investigate whether lymph node ratio (LNR) and log odds ratio (LODDS) have prognostic significance for overall survival (OS) and disease-free survival (DFS) in patients with laryngeal squamous cell cancer (LSCC) treated with curative intent.

Study Design: Case-control study.

Setting: University hospital.