High Capacity and Ultralong Lifespan Aqueous Lithium-Bromine Batteries Realized by Low-Cost Concentrated Electrolyte Coupled with Dependable Lithium Titanium Phosphate.

Aqueous halogen batteries are gaining recognition for large-scale energy storage due to their high energy density, safety, environmental sustainability, and cost-effectiveness. However, the limited electrochemical stability window of aqueous electrolytes and the absence of desirable carbonaceous hosts that facilitate halogen redox reactions have hindered the advancement of halogen batteries. Here, a low-cost, high-concentration 26 m Li-B-C-O aqueous solution incorporating lithium bromide (LiBr), lithium chloride (LiCl), and lithium acetate (LiOAc) was developed for aqueous batteries, which demonstrated an expanded electrochemical stability window of .

Design and validation of a real-time cassava planter seed quality monitoring system based on optical fiber sensors and rotary encoders.

Targeting the issues of seed leakage and cutting segment adhesion due to poor seed feeding and cutting in real-time seed-cutting cassava planters, this study developed a seeding quality monitoring system. Based on the structure and working principle of the seed cutting and discharging device, the installation methods of the matrix fiber optic sensor and rotary encoder were determined. By combining the operational characteristics of the planter's ground wheel drive with seed cutting and seed dropping, a monitoring model correlating the sowing parameters with seed dropping time was established; a monitoring window was created by extracting and processing the rotary encoder pulse signal, and the number of seeds sown after each opposing cutter's operation was calculated based on the pulse width information within the monitoring window.

Carbon dot-based nanomaterials with enzyme-like activity for fluorescence imaging and potential combination with therapy of cancer.

Carbon dot-based nanomaterials (o-CDs@Mn) were fabricated by assembling fluorescent o-CDs with enzyme-like activity and Mn nanoparticles with photothermal properties for realizing fluorescence imaging and combined therapy of cancer. Due to the inherent optical properties of o-CDs, o-CDs@Mn can be effectively used for bioimaging. In addition, o-CDs@Mn possess peroxidase-like (POD-like) and glutathione (GSH) degradation capabilities, which can effectively deplete excessive HO and GSH in the tumor microenvironment (TME), generating ·OH and reduced GSSH for regulating the TME and triggering ROS-mediated apoptosis in cancer cells.

Ensemble-Enhanced Semi-Supervised Learning With Optimized Graph Construction for High-Dimensional Data.

Graph-based methods have demonstrated exceptional performance in semi-supervised classification. However, existing graph-based methods typically construct either a predefined graph in the original space or an adaptive graph within the output space, which often limits their ability to fully utilize prior information and capture the optimal intrinsic data distribution, particularly in high-dimensional data with abundant redundant and noisy features. This paper introduces a novel approach: Semi-Supervised Classification with Optimized Graph Construction (SSC-OGC).

Multi-gene analysis of the crown clade (Russulales, Basidiomycota) revealed six new species and subsect. nov. from Fagaceae forests in China.

Introduction: The crown clade is one of two major groups in the subg. .

Methods/material: An analysis of Chinese samples was performed based on the morphology, internal transcribed spacer (ITS) sequences, and multi-gene phylogenies of 28S nrLSU, 16S mtSSU, , , and .

APOL1 High-Risk Genotype is Not Associated With New or Worsening of Proteinuria or Kidney Function Decline Following COVID-19 Vaccination.

Introduction: SARS-CoV-2 infection increases systemic inflammatory cytokines which act as a second-hit driver of Apolipoprotein L1 (APOL1)-mediated collapsing glomerulopathy. SARS-CoV-2 vaccination also increases cytokines. Recent reports of new glomerular disease in individuals with high-risk genotype (HRG) following SARS-CoV-2 vaccination raised the concern SARS-CoV-2 vaccination may also act as a second-hit driver of APOL1-mediated glomerulopathy.

Establishment of a nomogram model for predicting therapy complications in patients with polycythemia and deep venous thrombosis.

Background: Patients with deep venous thrombosis (DVT) residing at high altitudes can only rely on anticoagulation therapy, missing the optimal window for surgery or thrombolysis. Concurrently, under these conditions, patient outcomes can be easily complicated by high-altitude polycythemia (HAPC), which increases the difficulty of treatment and the risk of recurrent thrombosis. To prevent reaching this point, effective screening and targeted interventions are crucial.

Asymmetric Kinetic Resolution Polymerization of Racemic Lactide Mediated by Axial-Chiral Thiourea/Phosphazene Binary Organocatalyst.

Asymmetric kinetic resolution polymerization (AKRP) provides an ideal way to obtain highly isotactic polylactide (PLA) with superior thermal-mechanical properties from racemic lactide (rac-LA). However, the development of a new catalytic system with concurrent high activity and selectivity at ambient temperature remains a great callenge. Here, a series of simple and effective binary organocatalytic pairs containing axial-chiral thioureas and commercially available phosphazene bases were designed.

Application of multi-planar reconstruction technique in endovascular repair of aortic dissection.

Background: Endovascular repair of aortic dissection is an effective method commonly used in the treatment of Stanford type B aortic dissection. Stent placement during the operation was one-time and could not be repeatedly adjusted during the operation. Therefore, it is of great significance for cardiovascular physicians to fully understand the branch status, position, angle, and other information regarding aortic arch dissection before surgery.

Four new species of from the Xizang Autonomous Region and other provinces of China.

is the largest genus in the Russulales and is widespread throughout the world. Almost all species are known to be ectomycorrhizal with high ecological and edible values, and some are lethal poisonous. In this study, four new species belonging to the subgenus crown clade are identified based on morphological and phylogenetic evidence from the Xizang Autonomous Region and other provinces of China.

APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease.

Two coding variants of apolipoprotein L1 (APOL1), called G1 and G2, explain much of the excess risk of kidney disease in African Americans. While various cytotoxic phenotypes have been reported in experimental models, the proximal mechanism by which G1 and G2 cause kidney disease is poorly understood. Here, we leveraged 3 experimental models and a recently reported small molecule blocker of APOL1 protein, VX-147, to identify the upstream mechanism of G1-induced cytotoxicity.

Genetic and Molecular Evidence of a Tetrapolar Mating System in the Edible Mushroom .

is a valuable edible fungus with high nutritional and medicinal values. The mating systems of fungi not only offer practical strategies for breeding, but also have far-reaching effects on genetic variability. has been considered as a sexual species with a tetrapolar mating system based on little experimental data.

Phenothiazines Inhibit SARS-CoV-2 Entry through Targeting Spike Protein.

Novel coronavirus disease 2019 (COVID-19), a respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has brought an unprecedented public health crisis and continues to threaten humanity due to the persistent emergence of new variants. Therefore, developing more effective and broad-spectrum therapeutic and prophylactic drugs against infection by SARS-CoV-2 and its variants, as well as future emerging CoVs, is urgently needed. In this study, we screened several US FDA-approved drugs and identified phenothiazine derivatives with the ability to potently inhibit the infection of pseudotyped SARS-CoV-2 and distinct variants of concern (VOCs), including B.

Stability of SARS-CoV-2 in cold-chain transportation environments and the efficacy of disinfection measures.

Background: Low temperature is conducive to the survival of COVID-19. Some studies suggest that cold-chain environment may prolong the survival of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and increase the risk of transmission. However, the effect of cold-chain environmental factors and packaging materials on SARS-CoV-2 stability remains unclear.

The Involvement of Ubiquitination and SUMOylation in Retroviruses Infection and Latency.

Retroviruses, especially the pathogenic human immunodeficiency virus type 1 (HIV-1), have severely threatened human health for decades. Retroviruses can form stable latent reservoirs via retroviral DNA integration into the host genome, and then be temporarily transcriptional silencing in infected cells, which makes retroviral infection incurable. Although many cellular restriction factors interfere with various steps of the life cycle of retroviruses and the formation of viral latency, viruses can utilize viral proteins or hijack cellular factors to evade intracellular immunity.

Stereochemical Properties of Two Schiff-Base Transition Metal Complexes and Their Ligand by Using Multiple Chiroptical Spectroscopic Tools and DFT Calculations.

Two transition metal complexes were synthesized with Ni(II) and Cu(II) using a tetradentate Schiff-base ligand, (,) and (,)-,'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine. The stereochemical properties of the ligand and the metal complexes were investigated using a combined experimental and theoretical approach. Multiple spectroscopic techniques, which include IR, vibrational circular dichroism (VCD), UV-Vis and electronic circular dichroism (ECD), as well as Raman and the newly discovered ECD-circularly polarized Raman (i.

Optimal search mapping among sensors in heterogeneous smart homes.

There are huge differences in the layouts and numbers of sensors in different smart home environments. Daily activities performed by residents trigger a variety of sensor event streams. Solving the problem of sensor mapping is an important prerequisite for the transfer of activity features in smart homes.

Four New Species of Subsection from China.

Four new species of subsection from northern and southwestern China under coniferous and deciduous trees are proposed as , , , and . Illustrations and descriptions of , , , and the above four new species are provided based on evidence of morphological characters and phylogenetic analyses of the internal transcribed spacer (ITS), as well as the multi-locus of mtSSU, nLSU, , and -α. The relationships between these new species and allied taxa are discussed.

Intention affects fairness processing: Evidence from behavior and representational similarity analysis of event-related potential signals.

In an ultimatum game, the responder must decide between pursuing self-interest and insisting on fairness, and these choices are affected by the intentions of the proposer. However, the time course of this social decision-making process is unclear. Representational similarity analysis (RSA) is a useful technique for linking brain activity with rich behavioral data sets.

Morphological Characteristics and Phylogeny Reveal Six New Species in Subgenus () from Yanshan Mountains, North China.

Species of the genus are key components of ectomycorrhizal ecosystems worldwide, some of which are famous edible fungi. Although many new species have been described in China, their diversity in North China is still poorly known. Based on the morphology observation of specimens and molecular phylogenetic analyses, combined with the current classification frame of , six new species of subgenus are proposed from the Yanshan Mountains in northern Beijing and northern Hebei Province of China in this study: viz.

Plasma exosomal microRNA expression profiles in patients with high-altitude polycythemia.

High-altitude polycythemia (HAPC) is a chronic mountain sickness characterized by multiple severe ill-effects. Its pathogenesis is still unclear, and till date, no study has been conducted to investigate the plasma exome profile of Tibetan patients with HAPC. In this study, we aimed to elucidate the pathogenesis of HAPC by determining the microRNA (miRNA) signatures.

Acute depletion of human core nucleoporin reveals direct roles in transcription control but dispensability for 3D genome organization.

The nuclear pore complex (NPC) comprises more than 30 nucleoporins (NUPs) and is a hallmark of eukaryotes. NUPs have been suggested to be important in regulating gene transcription and 3D genome organization. However, evidence in support of their direct roles remains limited.

Numerical investigation on red blood cell flow based on unstructured grid.

Prediction of blood cell flow is known as the difficult research by reason of the complexity of blood vessel. In this study, considering the complex structure of blood vessels, a mechanical model for red blood cell (RBC) based on unstructured grid has been established to study the flow characteristics of RBCs in complex blood vessels. In the model, the strain-energy function by Skalak is employed to model the shear elasticity and surface-area conservation of the membrane, and the hinge spring is used to describe the forces originating from local bending of the membrane.

Cadophora species from marine glaciers in the Qinghai-Tibet Plateau: an example of unsuspected hidden biodiversity.

Large numbers of marine glaciers in the Qinghai-Tibet Plateau are especially sensitive to changes of climate and surface conditions. They have suffered fast accumulation and melting and retreated quickly in recent years. In 2017, we surveyed the cold-adapted fungi in these unique habitats and obtained 1208 fungal strains.

JAK inhibitor blocks COVID-19 cytokine-induced JAK/STAT/APOL1 signaling in glomerular cells and podocytopathy in human kidney organoids.

COVID-19 infection causes collapse of glomerular capillaries and loss of podocytes, culminating in a severe kidney disease called COVID-19-associated nephropathy (COVAN). The underlying mechanism of COVAN is unknown. We hypothesized that cytokines induced by COVID-19 trigger expression of pathogenic APOL1 via JAK/STAT signaling, resulting in podocyte loss and COVAN phenotype.