Up-regulation of IL-10 upon PRRSV vaccination impacts on the immune response against CSFV.

Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection negatively impacts the efficacy of classical swine fever virus (CSFV) vaccine. This paper investigates whether the PRRSV vaccine also impacts the CSFV vaccine and if the impact is time-related. Forty-eight piglets born from four sows were divided into five groups (G1-G5).

Phylogenetic characterization and virulence of two Newcastle disease viruses isolated from wild birds in China.

Wild birds are considered as a natural reservoir of Newcastle disease virus (NDV). However, there is no information about genotype IX NDV from wild birds, especially from Columbiformes. In this study, two genotype IX NDV viruses were isolated from wild birds.

Oral administration of attenuated Salmonella typhimurium containing a DNA vaccine against rabbit haemorrhagic disease.

The use of attenuated Salmonella typhimurium as a bactofection vehicle for the oral delivery of a DNA vaccine against rabbit haemorrhagic disease virus (RHDV) was investigated. The DNA vaccine plasmid pcDNA3.1-VP60, which encodes the viral capsid protein VP60, was transformed into the attenuated S.