Publications by authors named "Guohao Deng"
SO activates Th17 cells through the JAK1,2/STAT3 signaling pathway.
Int Immunopharmacol
December 2024
Article Synopsis
- The study looked at how a substance called SO affects certain immune cells in people with allergic rhinitis (AR) to find better treatments.
- The researchers tested blood samples from 15 AR patients and 15 healthy people to see how SO and a drug called Ruxolitinib changed the immune cell balance and some important proteins.
- The results showed that SO boosted immune cell activity in both AR patients and healthy individuals, but using Ruxolitinib reduced some of these effects, pointing to a possible way to treat AR.
Two-sample Mendelian randomization analysis of the causal relationship between blood eosinophils and allergic rhinitis.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
May 2024
Objectives: Previous studies have revealed a correlation between eosinophils and allergic rhinitis, but the causal relationship has not been fully confirmed. This study aims to evaluate the causal link between blood eosinophils and allergic rhinitis using the Mendelian randomization (MR) method.
Methods: Summary data from the Genome-Wide Association Study Catalog (GWAS) for eosinophil count (exposure variable) and allergic rhinitis (outcome variable) were collected.