Size-dependent selectivity and quantification on detecting PS nanoplastics particles in a mixed solution with different diameters by using periodic Ag nanocavities SERS substrates with high sensitivity.

Nanoplastic particles (NPPs) have attracted lots of attention due to their toxicity. In this study, a Surface-enhanced Raman scattering (SERS)-based category on selectivity and quantification detecting the polystyrene (PS) NPPs has been presented. Firstly, the size-dependent SERS relationship between the diameter of Ag nanocavities (AgNCAs) and the diameter of the PS NPPs is studied.

Blood routine test-based biomarkers is related to bone mineral density in elderly patients with chronic heart failure: A retrospective study.

Background: Our previous studies suggested that bone mineral density (BMD) correlated with the severity of chronic heart failure (HF) as classified by the New York Heart Association (NYHA) and that blood routine test (BRT)-based biomarkers, including hemoglobin, red blood cells (RBCs), lymphocytes, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, and systemic immune-inflammation index, were significantly related with BMD in general population.

Objective: This work aimed to evaluate the relationship between BRT-based biomarkers and BMD in elderly patients with chronic HF.

Methods: It was a retrospective study.

[Bioinformatics analysis of pathogenesis-associated protein Rv2387 in Mycobacterium tuberculosis].

Objective To predict and analyze the structure and function of the protein encoding the Mycobacterium tuberculosis (Mtb) Rv2387 gene by bioinformatics methods. Methods Basic information about the Rv2387 gene and the protein it encodes was obtained from the National Center for Biological Information (NCBI) database. Physicochemical properties and the hydrophilicity/hydrophobicity of proteins were predicted using ProtParam and ProtScale tools; TMHMM-2.

Predicting radiofrequency thermocoagulation surgical outcomes in refractory focal epilepsy patients using functional coupled neural mass model.

Objective: The success rate of achieving seizure freedom after radiofrequency thermocoagulation surgery for patients with refractory focal epilepsy is about 20-40%. This study aims to enhance the prediction of surgical outcomes based on preoperative decisions through network model simulation, providing a reference for clinicians to validate and optimize surgical plans.

Methods: Twelve patients with epilepsy who underwent radiofrequency thermocoagulation were retrospectively reviewed in this study.

One-step synthesized multisize AuAg alloy nanoparticles with high SERS sensitivity in directly detecting SARS-CoV-2 spike protein.

The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in widespread disease transmission, challenging the stability of global healthcare systems. Surface-enhanced Raman scattering (SERS) as an easy operation, fast, and low-cost technology illustrates a good potential in detecting SARS-CoV-2. In the study, one-step fabrication of gold-silver alloy nanoparticles (AuAgNPs) with adjustable metal proportions and diameters is employed as SERS substrates.

Host-Guest Interaction Mediated Perovskite@Metal-Organic Framework Z-Scheme Heterojunction Enabled Paper-Based Photoelectrochemical Sensing.

Exploring the high-performance photoelectronic properties of perovskite quantum dots (QDs) is desirable for paper-based photoelectrochemical (PEC) sensing;however, challenges remain in improving their stability and fundamental performance. Herein, a novel Z-scheme heterostructure with host-guest interaction by the confinement of CHNHPbBr QDs within Cu(BTC) metal-organic framework (MOF) crystal (MAPbBr@Cu(BTC)) is successfully constructed on the paper-based PEC device for ultrasensitive detection of Ochratoxin A (OTA), with the assistance of the exciton-plasmon interaction (EPI) effect. The host-guest interaction is estabilished by encapsulating MAPbBr QDs as guests within Cu(BTC) MOF as a host, which prevents MAPbBr QDs from being damaged in the polar system, offering access to long-term stability with high-performance PEC properties.

Fossils document evolutionary changes of jaw joint to mammalian middle ear.

The dual jaw joint of Morganucodon consists of the dentary-squamosal joint laterally and the articular-quadrate one medially. The articular-quadrate joint and its associated post-dentary bones constitute the precursor of the mammalian middle ear. Fossils documenting the transition from such a precursor to the mammalian middle ear are poor, resulting in inconsistent interpretations of this hallmark apparatus in the earliest stage of mammaliaform evolution.

Effects of Fe(II) and humic acid on U(VI) mobilization onto oxidized carbon nanofibers derived from the pyrolysis of bacterial cellulose.

The effects of Fe(II) and humic acid on U(VI) immobilization onto oxidized carbon nanofibers (Ox-CNFs, pyrolysis of bacterial cellulose) were investigated by batch, spectroscopic and modeling techniques, with results suggesting that, Ox-CNFs exhibited fast adsorption rate (adsorption equilibrium within 3 h), high adsorption performance (maximum adsorption capacity of 208.4 mg/g), good recyclability (no notable change after five regenerations) in the presence of Fe(II) towards U(VI) from aqueous solutions (e.g.

Acute Helicobacter pylori infection prevalence and association with metabolic abnormality in general Chinese population: A retrospective study.

Helicobacter pylori (H pylori) infection was common worldwide and previous researches on the correlation between H pylori infection and metabolic abnormality provided inconsistent conclusions. We assessed acute H pylori infection prevalence and the relationship with metabolic abnormality in general Chinese population. Participants attending for the physical examination underwent a carbon-13 urea breath test.

Evaluating magnetic resonance imaging characteristics and risk factors for hemifacial spasm.

Purpose: The specific neurovascular compression (NVC) event responsible for the symptomatic manifestation of hemifacial spasm (HFS) remains difficult to assess accurately using magnetic resonance imaging (MRI). We aim to evaluate the MRI characteristics of HFS.

Method: We retrospectively included patients with HFS and divided them into a test group (n = 186) and a validation group (n = 28).

Radiological characteristics predicting early poor drug response in patients with hemifacial spasm.

Objectives: Patients with hemifacial spasm (HFS) often resort to botulinum toxin injections or microvascular decompression surgery when medication exhibits limited effectiveness. This study aimed to identify MRI and demographic factors associated with poor drug response at an early stage in patients with HFS.

Methods: We retrospectively included patients with HFS who underwent pre-therapeutic MRI examination.

Operando Mobile Catalysis for Reverse Water Gas Shift Reaction.

Metal atoms on the support serve as active sites for many heterogeneous catalysts. However, the active metal sites on the support are conventionally described as static, and the intermediates adsorbed on the support far away from the active metal sites cannot be transformed. Herein, we report the first example of operando mobile catalysis to promote catalytic efficiency by enhancing the collision probability between active sites and reactants or reaction intermediates.

NK-derived exosome miR-1249-3p inhibits Mycobacterium tuberculosis survival in macrophages by targeting SKOR1.

Murine Natural Killer cells were cultivated in vitro to isolate NK-derived exosomes. Subsequent quantification via qPCR confirmed enrichment of miR-1249-3p. Ana-1 murine macrophages were cultured in vitro and subsequently inoculated with Mycobacterium tuberculosis (MTB) strain H37Rv.

MicroRNA-322 Attenuates Cartilage Matrix Degradation in Osteoarthritis via Direct Suppression of TRAF3.

Objective: Osteoarthritis (OA) is a degenerative joint disease. A growing number of studies have shown that microRNAs (miRNAs) play an important role in the pathogenesis of OA. However, the specific function of miR-322 in OA is unknown.

Halide solid-state electrolytes for all-solid-state batteries: structural design, synthesis, environmental stability, interface optimization and challenges.

Since the huge breakthrough in 2018, research on halide solid-state electrolytes (SSEs) has set off a new craze. In comparison with oxide and sulfide SSEs, halide SSEs have more balanced properties in various aspects, including ionic conductivity, electrochemical stability window, and moisture resistance. Herein, the overall knowledge and deep understanding of halide SSEs and their practical applications in all-solid-state batteries (ASSBs) are introduced.

Directly and ultrasensitivity detecting SARS-CoV-2 spike protein in pharyngeal swab solution by using SERS-based biosensor.

The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a great disaster to the economy and human society. Nowadays, SARS-CoV-2 is fading away from people's memory but it still exists around us. PCR plays an important role in detecting SARS-CoV-2 but it requires a long detecting time, equipped laboratory, and professional operators.

Bifunctional Strategy toward Constructing Perovskite/Upconversion Lab-on-Paper Photoelectrochemical Device for Sensitive Detection of Malathion.

Bifunctional nanocrystals which combine two kinds of materials into single nanoparticles hold great promise in photoelectrochemical (PEC) analysis, particularly for nanocrystals based on perovskite quantum dots (QDs) which generally exhibit excellent photoelectric activity yet poor stability and upconversion nanoparticles (UCNP) that normally suffer from negligible photoelectric activity. Therefore, to achieve good performance of the PEC bioassay platform, it is valuable to combine perovskite QDs with UCNP encapsulation and promote their advantages to form hybrid nanocrystals that are stable, NIR excitable, and photoelectric. Herein, the core-shell configuration of perovskite/upconversion CsPbBrI@NaYF:Yb,Tm (CPBI@UCNP) nanocrystals coupled with a NiMn-layered double hydroxide (NiMn-LDH)/CdS heterojunction to form a cascade sensitization structure was proposed to construct the lab-on-paper PEC device for ultrasensitive detection of malathion pesticides.

Nano-biosensor for SARS-CoV-2/COVID-19 detection: methods, mechanism and interface design.

The epidemic of coronavirus disease 2019 (COVID-19) was a huge disaster to human society. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which led to COVID-19, has resulted in a large number of deaths. Even though the reverse transcription-polymerase chain reaction (RT-PCR) is the most efficient method for the detection of SARS-CoV-2, the disadvantages (such as long detection time, professional operators, expensive instruments, and laboratory equipment) limit its application.

Monodisperse MoS/Graphite Composite Anode Materials for Advanced Lithium Ion Batteries.

Traditional graphite anode material typically shows a low theoretical capacity and easy lithium decomposition. Molybdenum disulfide is one of the promising anode materials for advanced lithium-ion batteries, which possess low cost, unique two-dimensional layered structure, and high theoretical capacity. However, the low reversible capacity and the cycling-capacity retention rate induced by its poor conductivity and volume expansion during cycling blocks further application.

Analysis of differentially expressed proteins after EHP-infection and characterization of caspase 3 protein in the whiteleg shrimp (Litopenaeus vannamei).

Whiteleg shrimp (Litopenaeus vannamei) is the most important species of shrimp farmed worldwide in terms of its economic value. Enterocytozoon hepatopenaei (EHP) infects the hepatopancreas, resulting in the hepatopancreatic microsporidiosis (HPM) of the host, which causes slow growth of the shrimp and poses a threat to the farming industry. In this study, differentially expressed proteins (DEPs) between EHP-infected and uninfected shrimp were investigated through proteomics sequencing.

Ready-to-use interactive dual-readout differential lateral flow biosensor for two genotypes of human papillomavirus.

Ready-to-use in vitro diagnosis of multiple genotypes is vital for the prevention and treatment of cervical cancer. Herein, a paper-film-based interactive dual readout differential lateral flow biosensor is proposed to simultaneously assay two high-risk types of human papillomavirus (HPV) within the body-fluid. The CuCoS/ZnInS heterostructure is fabricated on the paper-film compound chip with high thermostability, and surface sulfur vacancy is introduced by mild annealing treatment to endow unexceptionable photoexcitation activity, such structure can be served as an initial energy harvester and converter.