Publications by authors named "Guoding Li"

This study aimed to compare the biomechanical performance of an intramedullary nail combined with a reconstruction plate and a single intramedullary nail in the treatment of unstable intertrochanteric femoral fractures with a fracture of the lateral femoral wall (LFW). A three-dimensional finite element (FE) femur model was established from computed tomography images of a healthy male volunteer. A major reverse obliquity fracture line, associated with a lesser trochanteric fragment defect and a free bone fragment of the LFW, was developed to create an AO/OTA type 31-A3.

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Objective: The aim of this study was to evaluate the strength of the locking plate and lag screw construct that is applied in two different working lengths on the simple distal femur fracture model with a finite element analysis (FEA) method.

Methods: From the computerized tomography scan data of a 60-year-old healthy male, the AO/OTA 33A1-type fracture model was simulated; the fracture gap was stabilized with the models of locking plate construct with (groups C and D) or without an interfragmentary lag screw (groups A and B). Furthermore, 102-mm plate (groups A and C) and 82-mm plate working lengths (groups B and D) were tested using FEA.

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Chronic exposure to cadmium compounds (Cd(2+)) is one of the major public health problems facing humans in the 21st century. Cd(2+) in the human body accumulates primarily in the kidneys which leads to renal dysfunction and other adverse health effects. Efforts to find a safe and effective drug for removing Cd(2+) from the kidneys have largely failed.

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We are interested in the detection of DNA adducts and other trace analytes by labeling them with a fluorescent tag followed by use of capillary electrophoresis with laser-induced fluorescence detection (CE-LIF) for high resolution and sensitivity. Towards this goal, here we report the following: (1) synthesis and handling properties of a near-IR, carboxyl-substituted heptamethine cyanine dye; (2) modification of an existing ball lens LIF detector to provide near-LIF detection with excitation at 785 nm for CE; and (3) corresponding handling and detection of as little as 0.8 amol of the dye by enrich-injection of 4.

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