Age and Mutation Stratified Patients with Cytologically Benign Thyroid Nodules.

Purpose: Our objective was to evaluate the diagnostic performance of mutation for malignant, and to identify clinical characteristics associated with positive mutation in low-risk cytological and ultrasound diagnostic thyroid nodules. This aims to identify patients who may benefit from mutation testing and subsequent surgical intervention.

Patients And Methods: We analysis the clinical characteristics correlated with mutation in our detection cohort, including 204 patients with 217 thyroid nodules, and separate analyses were performed in 103 thyroid nodules with benign cytological result.

Dual-grafted dextran based nanomicelles: Higher antioxidant, anti-inflammatory and cellular uptake efficiency for quercetin.

Quercetin (QCT) has antioxidant, anti-inflammatory, anti-tumor and other important pharmacological activities, but the poor water solubility limits its application. In this work, the amphiphilic dextran (ADEX) was prepared by grafting L-cysteine and octadecylamine onto carboxymethyl dextran with the grafting rate of 21.29 % and 19.