Publications by authors named "Guobin Hou"

Article Synopsis
  • Disorders of acid-base balance in the rumen of dairy cows can notably influence their health and performance, particularly in relation to subacute ruminal acidosis (SARA) and the production of inflammatory compounds like lipopolysaccharides (LPS).
  • This study compared 40 Holstein dairy cows based on their rumen pH levels two to four hours after feeding, categorizing them into low pH (LPH) and high pH (HPH) groups, to analyze the relationship between pH, microbiomes, and inflammatory responses.
  • The findings indicated that cows in the LPH group exhibited higher concentrations of various fatty acids and inflammatory markers, along with significant changes in microbial populations, which suggests that lower rum
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  • The study focuses on how a mother cow's gut microbiome influences the development of her newborn calf's gut microbiome, particularly looking at differences based on the mother's physiological traits.
  • Researchers used a cow-to-calf model to analyze and categorize the microbial communities found in both the rumen (stomach) and feces of dairy cows, finding significant differences tied to the cows’ production performance.
  • Findings indicated that beneficial bacteria and metabolic functions are passed from mothers to calves, emphasizing the rumen as a key source of microbial transmission, along with shared antibiotic-resistance traits.
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  • Researchers studied how certain harmful genes (VFGs) in dairy cattle can affect animal health and the environment.
  • They collected samples from cows, calves, colostrum, farm wastewater, and soil to see how these genes spread and change.
  • The findings showed that VFGs were different in cow waste and their stomachs, influenced by diet and region, and that caring for newborn calves can increase the number of these genes in their poop.
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The dominant bacteria in the hindgut of calves play an important role in their growth and health, which could even lead to lifelong consequences. However, the identification of core probiotics in the hindgut and its mechanism regulating host growth remain unclear. Here, a total of 1045 fecal samples were analyzed by 16S rRNA gene sequencing from the 408 Holstein dairy calves at the age of 0, 14, 28, 42, 56, and 70 days to characterize the dynamic changes of core taxa.

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Oxidative stress damage in periparturient cows decreases both production and their health; supplementation with complex additives during the periparturient period has been used as an important strategy to enhance the antioxidant status and production of dairy cows. The periparturient cows not only risk a negative energy balance due to reduced dry matter intake but also represent a sensitive period for oxidative stress. Therefore, we have developed an immunomodulatory and nutritional regulation combined additive (INC) that hopefully can improve the immune status and production of cows during the periparturient period and their offspring health and growth by improving their antioxidant stress status.

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Ticks are medically-important arthropods that maintain and transmit numerous emerging viruses. China suffers severely from tick-borne viral diseases such as tick-borne encephalitis and severe fever with thrombocytopenia syndrome (SFTS), but the background of tick-borne viruses is very limited. Here we report the virome profiling of ticks and goat sera from SFTS-epidemic areas, and serological investigation of SFTS virus (SFTSV) and Nairobi sheep disease virus (NSDV).

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