Publications by authors named "Guobiao Pan"
Evidence indicates that the use of sedative-hypnotics, including benzodiazepines and z-drugs, is linked to an increased risk of falls and fractures. Nonetheless, the potential exacerbation of this risk by orexin receptor antagonists, which are novel therapeutic agents for treating insomnia, remains uncertain despite their escalating prevalence in clinical practice. We systematically searched four electronic databases from inception to April 17, 2024.
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- This study looked at how temperature affects visits to the emergency room for broken bones.
- Researchers found that when it gets really hot (above 9.5 °C), more people show up at the hospital with fractures.
- Men and people aged 18-65 are more likely to get hurt in high temperatures compared to others.
Article Synopsis
- The study aimed to compare the effectiveness of two surgical methods for treating popliteal cysts: arthroscopic drainage and resection.
- A total of 54 patients, aged 44 to 72, were treated, with 24 undergoing drainage (group A) and 30 receiving resection (group B), followed up for up to 2 years to assess outcomes like pain relief and knee function.
- Both methods showed significant improvement in symptoms, with minimal complications; however, drainage had a shorter operation time and less bleeding compared to resection, though some patients in the drainage group experienced a recurrence of cysts.
Objective: To explore clinical effect of lateral locking compression plate combined with medial buttress plate in treating osteoporotic comminuted fractures of proximal humerus.
Methods: From May 2017 to December 2021, 12 patients with osteoporotic comminution of proximal humerus were treated by lateral locking compression plates combined with medial buttress plates, including 5 males and 7 females, aged from 55 to 78 years old, bone mineral density(BMD) less than -2.5 g/cm3, the time from injury to operation was from 2 to 6 days.
Objective: To investigate the diagnosis and treatment of intraosseous ganglion cyst in the ankle region.
Methods: A retrospective analysis was performed on the diagnosis and treatment of 18 patients with intraosseous ganglion in the ankle region from January 2005 to March 2016. There were 11 males and 7 females, with an average age of 40.
To aim of the present paper was to introduce a novel fixation technique for the treatment of inferior pole fracture of the patella. We performed a prospective observational study of consecutive cases of inferior pole fracture of the patella that were treated at our institution between January 2018 and June 2019. The patients include three men and one woman, with an average age of 47 years (range: 42-59 years).
View Article and Find Full Text PDFMicroRNA-106a-5p (miR-106a-5p) functions as a tumor suppressor in osteosarcoma cells. Here, we aimed to identify novel target genes of miR-106a-5p in osteosarcoma, as well as to investigate their prognostic value and the biological functions. At first, the mammalian runt-related factor 1 (RUNX1) was identified as one of the target genes of miR-106a-5p in osteosarcoma cells by luciferase reporter gene assay, real-time quantitative RT-PCR and Western blot analysis.
View Article and Find Full Text PDFMicroRNA-136 functions as a tumor suppressor in osteosarcoma via regulating metadherin.
Cancer Biomark
October 2018
Background: Accumulating studies have reported the abnormal expression of microRNA-136 (miR-136) in numerous types of human cancer, and its involvement in cancer initiation and progression. However, there are no investigations of miR-136 in osteosarcoma (OS).
Objective: To explore the expression pattern, clinical significance and potential roles of miR-136 in OS.
Objective: To evaluate clinical outcomes of fixation for the treatment of radial head fracture with collapse of anterior articular surface.
Methods: From March 2006 to January 2013,17 patients with radial head fractures with collapse of anterior articular surface were analysed. According to the Mason classification, there were 12 cases with Mason type II fractures and 5 cases with Mason type III fractures.
Objective: To compare clinical effects between plaster fixation and cannulated screw for the treatment of Jones fracture.
Methods: From 2006 to 2010, 41 patients with Jones fractures were divided into 2 groups. In Group A, there were 14 males and 8 females, ranging in age from 21 to 62 years, with an average of (32.
[Diagnosis and treatment of the coronal fracture of the femoral condyle].
Zhongguo Gu Shang
October 2008
Objective: To investigate the diagnosis and treatment of the coronal fracture of the femoral condyle.
Methods: Seven patients with Hoffa fracture treated in our hospital in recent 7 years were enrolled in this study. Six patients were treated with surgical treatment, while one non-displaced fracture received conservative treatment.
[Endothelium-independent vasorelaxant effect of puerarin on rat thoracic aorta].
Zhongguo Zhong Yao Za Zhi
October 2004
Objective: To investigate the vasorelaxant effect of puerarin in rat aortic rings and the mechanism.
Method: The isolated thoracic aortic rings of male Sprague-Dawley rats were mounted on the organ bath and the contractile responses of the vessel were recorded.
Result: Puerarin completely relaxed the contractions induced by phenylephrine in a concentration-dependent manner in endothelium-intact and endothelium-denuded rat aorta, but it had no effect on those preconstricted by a high concentration of potassium chloride (KCl, 60 mmol x L(-1)).