The Lotus corniculatus MYB5 functions as a master regulator in proanthocyanidin biosynthesis and bioengineering.

PAs varied greatly in leaves of different germplasm accessions in Lotus corniculatus and over-expression of LcMYB5 led to high PA accumulation in L. japonicus hairy roots. Proanthocyanidins (PAs) content in leaves is an important quality trait in forage species.

Intracranial mesenchymal tumor with multiple extracranial metastases: A case report and literature review.

This study presents a rare case of an older woman with an intracranial mesenchymal tumor in the right frontal and parietal lobes. Despite prompt surgical intervention, her condition rapidly deteriorated because of tumor dissemination, leading to her demise. We highlight the tumor's marked invasiveness and heterogeneity, coupled with a propensity for distant systemic metastasis, which negatively impacted the patient's prognosis.

Time-series transcriptome provides insights into the gene regulation network involved in the icariin-flavonoid metabolism during the leaf development of .

Herba Epimedii (Epimedium) leaves are rich in prenylated flavonol glycosides (PFGs) with high medicinal value. However, the dynamics and regulatory network of PFG biosynthesis remain largely unclear. Here, we combined metabolite profiling (targeted to PFGs) and a high-temporal-resolution transcriptome to elucidate PFGs' regulatory network in and identified key candidate structural genes and transcription factors (TFs) involved in PFG accumulation.

A Novel 3--rhamnoside: 2″--xylosyltransferase Responsible for Terminal Modification of Prenylflavonol Glycosides in Maxim.

Prenylated flavonol glycosides in plants, as key medicinal components, are known to have great pharmaceutical activities for human health. Among the main prenylated flavonol glycosides, the modification mechanism of different sugar moieties is still not well understood. In the current study, a novel prenylated flavonol rhamnoside xylosyltransferase gene () was cloned from , and the enzymatic activity of its decoding proteins was examined in vitro with different prenylated flavonol rhamnoside substrates and different 3--monosaccharide moieties.

Single-cell RNA sequencing provides a high-resolution roadmap for understanding the multicellular compartmentation of specialized metabolism.

Monoterpenoid indole alkaloids (MIAs) are among the most diverse specialized metabolites in plants and are of great pharmaceutical importance. We leveraged single-cell transcriptomics to explore the spatial organization of MIA metabolism in Catharanthus roseus leaves, and the transcripts of 20 MIA genes were first localized, updating the model of MIA biosynthesis. The MIA pathway was partitioned into three cell types, consistent with the results from RNA in situ hybridization experiments.

[Rapid prediction of flavonoid content in Epimedium sagittatum by infrared spectroscopy].

Epimedii Folium is a well-known Chinese herbal medicine with the effect of nourishing kidney and strengthening Yang. Its main active ingredients are flavonoids. In this study, 60 samples of Epimedium sagittatum were collected for the determination of total flavonoids(TF) including the total amount of epimedin A, epimedin B, epimedin C, and icariin(abbreviated as ABCI) specified in the Chinese Pharmacopoeia as well as rhamnosylicariside Ⅱ and icariside Ⅱ.

The discovery of a key prenyltransferase gene assisted by a chromosome-level genome.

is a species of the family Berberidaceae in the basal eudicot lineage, and a main plant source for the traditional Chinese medicine "Herba Epimedii". The current study achieved a chromosome-level genome assembly of with the genome size of 3.34 Gb, and the genome guided discovery of a key prenyltransferase (PT) in .

New 8-prenylated quercetin glycosides from the flowers of and their testosterone production-promoting activities.

Phytochemical investigation was carried out for the flowers of Franchet. by first conducting LC-MS analysis, leading to the identification of 32 compounds. Furthermore, guided by LC-MS profiling, three new 8-prenylated quercetin glycosides (3'-hydroxylikarisoside C, 3'-hydroxylepimedoside E, 3'-hydroxyldiphylloside B), one new anthocyanin (delphinidin-3---coumaroyl-sophoroside) and six known compounds were isolated from the flowers of for the first time, and their structures were characterized based on spectroscopic methods including 1D and 2D NMR, and HRESIMS.

Genome-wide analysis of gene family identified key gene for the biosynthesis of bioactive flavonol glycosides in Maxim.

Maxim. is a well-known traditional Chinese medicinal herb with flavonol glycosides as the major pharmaceutically active compounds. UDP-glycosyltransferases (UGTs) are a group of enzymes responsible for the glycosylation of flavonoid glycosides.

[Content correlation of eight phenolic acids and flavonoids in different medicinal parts of PA-type Perilla germplasms].

In this study, 10 PA-type Perilla germplasms were selected to detect the content of two phenolic acids, i.e., rosmarinic acid(RA) and caffeic acid(CA), and six flavonoids, including scutellarin-7-O-diglucuronoside(SDG), luteolin-7-O-diglucuronoside(LDG), apigenin-7-O-diglucuronoside(ADG), scutellarin-7-O-glucuroside(SG), luteolin-7-O-glucuroside(LG), and apigenin-7-O-glucuroside(AG) in leaves, stems, and fruits.

The complete chloroplast genome of (Koidz.) Koidz. (Berberidaceae).

L. is an important genus in the family Berberidaceae. (Koidz.

The complete chloroplast genome of Ogisu (Berberidaceae), a rare plant species endemic to China.

L. is an important medicinal herbaceous genus that belongs to the family Berberidaceae. Ogisu is a plant species only inhabited in the northwestern part of Sichuan province, China.

The complete chloroplast genome of Franch. (Berberidaceae), a rare plant species endemic to China.

L. is a medicinally important herbaceous genus in the family Berberidaceae. Franch.

The complete chloroplast genome of K. Mey. (Berberidaceae), a rare plant species from China.

L. is an important medicinal herbaceous genus in the family Berberidaceae. K.

The complete chloroplast genome of Franch. (Berberidaceae).

L. is the largest herbaceous genus in the family Berberidaceae which comprises more than 60 species. Franch.

Identification of Transcription Factor Genes and Functional Characterization of From .

Kudzu, , is a traditional Chinese food and medicinal herb that has been commonly used since ancient times. Kudzu roots are rich sources of isoflavonoids, e.g.

Genome-Wide Analysis of Glycoside Hydrolase Family 35 Genes and Their Potential Roles in Cell Wall Development in .

Plant β-galactosidases (BGAL) function in various cell wall biogeneses and modifications, and they belong to the glycoside hydrolase family. However, the roles of BGAL family members in cell wall remodeling remain unclear. In this study, a total of 25 members of the glycoside hydrolase gene family 35 were identified, and they were clustered into nine sub-families.

Gene Encodes a Flavonoid Prenyltransferase in White Lupin.

Legume plants are rich in prenylated flavonoid compounds, which play an important role in plant defense and human health. In the present study, we identified a prenyltransferase (PT) gene, named , in white lupin (), which shows a high identity and close relationship with the other known PT genes involved in flavonoid prenylation in planta. The recombinant LaPT2 protein expressed in yeast cells exhibited a relatively strong activity toward several flavonols (e.

The complete chloroplast genome of (Berberidaceae), a narrowly distributed plant species in China.

L. is the largest herbaceous genus of Berberidaceae which comprises more than 60 species. is a rare plant species only narrowly inhabited in the Puding County in the Guizhou Province of China.

The complete chloroplast genome of B. L. Guo et Hsiao (Berberidaceae).

The genus of belongs to Berberidaceae family, which is famous for their medicinal and ornamental value. In recent years, has attracted increasing attention due to their medicinal and nutritive value. In this research, we reported the complete chloroplast (cp) genome of The complete chloroplast of this species is 157,076 bp in length, including a pair of invert repeat regions (IRS) (25,833 bp) that is divided by a large single copy area (LSC) (88,340 bp) and a small single copy area (SSC) (17,070 bp).

The complete chloroplast genome of Y. J. Zhang (Berberidaceae).

, a critically endangered herb with limited population, mainly distributes in Sichuan province, China. In our study, we obtained the complete chloroplast genome of with a length of 158,955 bp, including a large single copy region of 86,478 bp, small single copy region of 17,027 bp, and a pair of inverted repeat regions of 27,725 bp. The GC content in the whole chloroplast genome of is 38.

The complete chloroplast genome of (Berberidaceae).

In this study, the complete chloroplast (cp) genome of was sequenced and assembled. The circular genome is 157,066 bp in size. The whole chloroplast genome of contains 112 unique genes, of which 78 protein-coding genes, 30 tRNA genes, and four rRNA genes.

The complete chloroplast genome of (Berberidaceae), a traditional Chinese medicinal herb.

Epimedii Folium has been used as a common traditional Chinese medicine for more than 2000 years in China. In this study, we assembled the complete chloroplast (cp) genome of . The whole cp genome of is 158,658 bp in length, comprising a pair of inverted repeat (IR) regions (27,699 bp) separated by a large single copy (LSC) region (86,558 bp) and a small single copy (SSC) region (16,702bp).

The complete chloroplast genome of T. S. Ying. (Berberidaceae), a traditional Chinese medicinal herb.

is a well-known medicinal plant in Berberidaceae in China. In this study, we sequenced the complete chloroplast (cp) genome of . The results showed that the cp genome of was 157,283 bp in length, which is composed of a large single-copy region (LSC, 88,579 bp) and a small single-copy region (SSC, 17,082 bp) that were separated by a pair of inverted repeat regions (IRa and IRb, 25,811 bp).