Analysis of Breast Cancer Screening Results and Influencing Factors of Breast Cancer in Guangdong Province from 2017 to 2021.

Backgrounds: Breast cancer screening plays an important role in the early detection, diagnosis and treatment of breast cancer. The aim of this study was to evaluate the screening results and explore the influencing factors of breast cancer detection rate in Guangdong.

Methods: This cross-sectional study was conducted among 2,024,960 women aged 35-64 in Guangdong Province during 2017-2021.

In vivo measurement of regional corneal tangent modulus.

Currently available clinical devices are unable to measure corneal biomechanics other than at the central region. Corneal stiffness (S), thickness, and radius of curvature was measured at the central cornea (primary fixation) and 3 mm from the temporal limbus (primary and nasal fixations). The corneal tangent modulus (E) of 25 healthy subjects was calculated from these data.

Development of ocular viscosity characterization method.

Glaucoma is the second leading cause for blindness. Irreversible and progressive optic nerve damage results when the intraocular pressure (IOP) exceeds 21 mmHg. The elevated IOP is attributed to blocked fluid drainage from the eye.

High myopes have lower normalised corneal tangent moduli (less 'stiff' corneas) than low myopes.

Purpose: To compare corneal tangent moduli between low and high myopes.

Methods: Corneal hysteresis (CH) and corneal resistance factor (CRF) of 32 low and 32 high myopes were obtained using an Ocular Response Analyzer, followed by a corneal indentation device that measured corneal stiffness. Corneal topography, pachymetry, Goldmann applanation tonometry intraocular pressure (GAT-IOP), and corneal compensated intraocular pressure (IOPcc) were also obtained.

Diurnal Variation of Corneal Tangent Modulus in Normal Chinese.

Purpose: The aim of this study was to investigate the diurnal variation of corneal tangent modulus, measured using a novel corneal indentation device, in healthy Chinese subjects.

Methods: The central corneal thickness (CCT), mean central corneal radius (meanK), intraocular pressure (IOP), and corneal stiffness of 25 young adults aged 21 to 25 years (23.0 ± 1.

Soft wearable contact lens sensor for continuous intraocular pressure monitoring.

Intraocular pressure (IOP) is a primary indicator of glaucoma, but measurements from a single visit to the clinic miss the peak IOP that may occur at night during sleep. A soft chipless contact lens sensor that allows the IOP to be monitored throughout the day and at night is developed in this study. A resonance circuit composed of a thin film capacitor coupled with a sensing coil that can sense corneal curvature deformation is designed, fabricated and embedded into a soft contact lens.

Effect of Xinjikang on left ventricular hypertrophy remodeling in hypertensive rats.

Objective: To investigate the effects of Xinjikang on the left ventricular hypertrophy remodeling and myocardial activity in hypertension.

Methods: Sixty Wistar rats were randomly divided into four groups. The pressure-loaded left ventricular hypertrophy model was established with abdominal aorta ligation method.

Multi-factorial analytical study on real-time three-dimensional echocardiographic cardiac image display quality.

Although real-time three-dimensional echocardiography (RT-3DE) can display stereoscopic images, its acquisition and image display quality are affected by many factors. So, the study aimed to evaluate the importance of factors affecting the efficiency of RT-3DE image display quality, and establish an optimized method for RT-3DE examination and image processing in children. Based on the specific cardiac acoustic characteristics in children, 83 healthy children were studied and divided into five groups.

Echocardiographic assessment of juxtaposition of the right atrial appendage in children with congenital heart disease.

The objective of this study was to analyze the echocardiographic characteristics of juxtaposition of the atrial appendages and to determine its prevalence in children with congenital heart disease. From June 1998 to December 2008, 10,880 children underwent selective angiocardiography, magnetic resonance imaging (MRI), and echocardiography for evaluation of congenital heart disease. Juxtaposition of the atrial appendages was diagnosed based on the results of angiocardiography and MRI; the echocardiographic characteristics of this anomaly were analyzed retrospectively.

Echocardiographic assessment of conjoined twins with congenital heart disease in Shanghai.

Background: The aim of this study is to improve the diagnosis of congenital heart disease in conjoined twins using echocardiography.

Methods: Six sets of conjoined twins at Shanghai Children's Medical Center and Xin-Hua Hospital from 1980 to 2006 were assessed retrospectively. Cardiac anomalies of varying degrees of severity were first evaluated using 2D echocardiography.

Doppler myocardial performance index in assessment of ventricular function in children with single ventricles.

Background: Quantitative assessment of ventricular function in children with single ventricles is both difficult and subjective because of asymmetric ventricular geometry. The Doppler myocardial performance index (MPI) allows the assessment regardless of ventricular shape. This study was designed to evaluate the feasibility of MPI in assessing ventricular function in children with single ventricles before and after total cavopulmonary connection (TCPC).

Value of real-time 3-dimensional echocardiography sectional diagnosis in complex congenital heart disease evaluated by receiver operating characteristic analysis.

Objective: We sought to evaluate the value of real-time 3-dimensional (3D) echocardiography (RT-3DE) in the pathologic morphology of complex congenital heart disease (CHD) using receiver operating characteristic (ROC) analysis.

Methods: Thirty patients with complex CHD were examined by 2-dimensional echocardiography (2DE) and RT-3DE. Their diagnoses of pathologic morphology were made by 3 echocardiographers blinded to clinical data.

Methodological study on real-time three-dimensional echo-cardiography and its application in the diagnosis of complex congenital heart disease.

Background: Real-time three-dimensional echocardiography (RT-3DE) has made revolutionized improvements of cardiac imaging during the past few years. However, there is no standard examination method for RT-3DE so far. This study aimed to establish the diagnostic method of RT-3DE and evaluate its application in the diagnosis of complex congenital heart diseases (CHD).

[Pathological diagnosis of conotruncal defects by transthoracic three-dimensional echocardiography].

Objective: Recently, it has been demonstrated in several studies that three-dimensional echocardiography (3DE) with any cut view interpretation of the cardiac morphological structures and its dynamic three-dimensional display can conform to the need of accurate anatomical diagnosis of complex congenital heart diseases including conotruncal defects (CTD). 3DE can not only provide functional and morphological information of CTD to decide on surgical repair but also simulate the intra operative visualization of complex anatomical cardiac structures to improve the understanding of the anatomy of CTD, but there have been scarce studies to assess systematically the potential noninvasive diagnostic value of transthoracic 3DE for CTD in children. Thus, this study attempted to evaluate the diagnostic value of transthoracic 3DE for the pathological diagnosis of CTD in children.