Aerobic oxidative acylation of nitroarenes with arylacetic esters under mild conditions: facile access to diarylketones.

A facile and regioselective base-mediated aerobic oxidative acylation of nitroarenes to access diarylketones under mild conditions has been developed. It features the use of bench-stable and readily available arylacetates as acyl surrogates, and the absence of transition-metals and synthetic oxidants. This protocol involves a cascade CDC/oxidative decarboxylation process.

Clinical experience in diagnosis and treatment of malignant gastrointestinal stromal tumors.

This study investigated the clinical pathologic character of malignant gastrointestinal stromal tumors (MGIST), their treatment with surgery, and evaluated the efficacy of imatinib postoperation. A total of 68 MGIST patients were enrolled. Of these, 27 patients underwent imatinib auxiliary therapy (treatment group) and 41 underwent imatinib therapy (control group).

Retrospective analysis of 76 immunocompetent patients with primary pulmonary cryptococcosis.

Background: Pulmonary cryptococcosis typically occurs in immunocompromised patients, but it can also occur in immunocompetent patients. Our objective was to describe the clinical manifestations, diagnosis, and management of primary pulmonary cryptococcosis in immunocompetent patients.

Methods: We retrospectively reviewed the clinical data of 76 patients with primary pulmonary cryptococcosis who were admitted to our hospital from 1995 to 2010.

[Follicular dendritic cell sarcoma: a clinicopathologic analysis of ten cases].

Objective: To study the clinicopathologic features of follicular dendritic cell sarcoma (FDCS) and its differential diagnosis.

Methods: Ten cases of FDCS were studied by light microscopy, immunohistochemistry and in-situ hybridization. The clinical features and follow-up information were analyzed.

[Effects of partial revascularization in elderly patients over 80 years old with coronary artery diseases].

Objective: To observe the clinical effects of partial revascularization on elderly patients with coronary artery diseases(CAD) METHODS: Percutaneous coronary interventions (PCI) of the most likely culprit vessels were performed in 37 patients over 80 years old with multivessel coronary artery diseases (CAD).

Results: The success rate of PCI was 100% in these elderly patients without serious complications. The in-hospital mortality rate was 2.

[Clinical analysis of 60 cases with malignant gastrointestinal stromal tumors].

Objective: To investigate the clinicopathological characteristics, and treatment of malignant gastrointestinal stromal tumors (MGIST).

Methods: Immunohistochemistry was used to detect CD117, CD34, S100, vimentin and SMA expressions. The postoperative curative effect was compared between the patients with or without imatinib treatment.

[Pathological analysis of breast carcinoma after silicone gel injection].

Objective: To explore the correlation between breast carcinoma and silicone gel injection for breast augmentation.

Methods: Four cases of breast cancer after silicone gel injection were studied by means of clinical pathological analysis.

Results: In the four women, breast lump of over 5 cm in diameter was found half year to 2 years after silicone injection.

[Pathological changes of lungs in patients with severity acute respiratory syndrome].

Objective: To evaluate the progression in morphologic changes of lungs in SARS patients.

Methods: Four cases of SARS with lung tissue samples available (including one for ultrastructural examination) were enrolled into the study. Histochemical study for VG, Masson, reticulin, orcein, PAS, sirius red stains and immunohistochemical study for vimentin, desmin, smooth muscle actin, HHF-35, CD34, F8, collagen types I and III were also performed.