Publications by authors named "Guo-ping Lian"
Prediction of human skin permeability using artificial neural network (ANN) modeling.
Acta Pharmacol Sin
April 2007
Article Synopsis
- The study aimed to create an artificial neural network (ANN) model to predict skin permeability (log K(p)) for new chemicals.
- A dataset of 215 experimental results was used, splitting it into subsets for training and validating the ANN model and a multiple linear regression (MLR) model.
- Results showed the ANN model outperformed the MLR model, indicating a non-linear relationship between log K(p) and Abraham descriptors, confirming their potential for predicting skin permeability.