Surgical Treatment for Severe Primary Midbrain and Upper Pons Hemorrhages Using a Subtemporal Tentorial Approach.

 It is unclear whether surgical hematoma evacuation should be performed in cases of primary brainstem hemorrhages (PBH). Here, we analyzed 15 cases with severe primary midbrain and upper pons hemorrhages to assess the associations between the subtemporal tentorial approach and patient functional outcomes and mortality.  A total of 15 patients diagnosed with severe primary midbrain and upper pons hemorrhages who had previously received the subtemporal tentorial approach at our facility from January 2018 and March 2019 were analyzed.

Analysis of regulatory networks constructed based on gene coexpression in pituitary adenoma.

Gene coexpression patterns can reveal gene collections with functional consistency. This study systematically constructs regulatory networks for pituitary tumours by integrating gene coexpression, transcriptional and posttranscriptional regulation. Through network analysis, we elaborate the incidence mechanism of pituitary adenoma.

[Neuronavigation-assisted microanatomical study of the facial nerve canal through the transpetrosal approach].

Objective: To study the value of neuronavigation in the transpetroal approach, and to provide anatomic data for the protection of the nerves in the facial nerve canal (FNC) during surgeries.

Methods: Simulated surgery through the transpetroal approach was performed on 16 sides of 8 adult cadaver heads with the assistance by neuronavigation. The anatomy of the facial nerve and the relationship of related structures were observed and the distances from the utmost external edge of the mastoid to different segments of the FNC were measured.

Early diagnosis of cerebral infarction with near-infrared spectroscopy: an experimental study.

Objective: To monitor the changes in the blood flow and blood-oxygen content in rat cerebral tissue with focal cerebral infarction using near-infrared spectroscopy (NIRS), so as to verify the value of NIRS in early diagnosis of cerebral infarction.

Methods: Focal cerebral infarction models were established in 16 rats by injecting silk threads into the internal carotid artery. The bilateral blood flow and blood-oxygen content were monitored with NIRS in the models and also in 16 normal rats receiving saline injection to serve as blank control group.

Microanatomical and neuroendoscopic studies of the internal auditory meatus and its surrounding structures.

Objective: To observe the morphology of the internal auditory meatus in relation with its surrounding structures in Chinese people, for the purpose of providing microanatomical reference for surgeries adopting retro-sigmoid approach.

Methods: The retro-sigmoid surgical approach was simulated on 5 fresh specimens of human head, in which the internal auditory meatus and its surrounding structures were observed through a neuroendoscope and a surgical microscope. The distances from the posterior inferior edge of the internal auditory meatus to the central point of the posterior edge of the sigmoid sinus and to the posterior edge of the posterior semicircular canal were measured.