Publications by authors named "Guo-hua Peng"

Objective: To develop a bionic animal skin and evaluate its detective effect of cercariae so as to provide a new technique for the monitoring of the schistosome susceptibility water body.

Methods: A bionic animal skin was made with pigskin and the experiments were carried out for evaluating its detective effects of cercariae in laboratory and simulate fields, and at the same time, the sentinel mouse method was used as the control.

Results: In the laboratory, the cercariae were found in 10-, 30-, 60-cercaria subgroups in the bionic animal skin group after 1 and 2 hours, but the cercariae were found only in the 60-cercaria subgroup in the sentinel mouse group.

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To improve the management level of patients' information of schistosomiasis control stations in Nanchang City, the B/S three-layer architecture and ASP+SQL technology were applied to formulate the WEB-based management system of chronic schistosomiasis patients' information, so as to achieve the information sharing of chronic schistosomiasis among schistosomiasis control stations.

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Objective: To understand the present situation of the chronic schistosomiasis patients' knowledge, attitude and practice on schistosomiasis control in Nanchang City.

Methods: The knowledge, attitude and values on schistosomiasis control of 523 chronic schistosomiasis patients in Nanchang County, Jinxian County and Xinjian District in the Poyang Lake District were investigated with questionnaires. And the accuracy rates of the knowledge, attitude and practice among the patient groups of different counties, genders, age groups, occupations and educational levels were analyzed.

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Objective: To investigate the endemic situation of human infection in Nanchang City in 2014 and analyze the influencing factors, so as to provide the evidence for control measures.

Methods: The high-risk population of infection in Nanchang City was collected as an experiment group, and a control group was settled with the ratio of 1∶1. The serum tests and epidemiology surveys were conducted simultaneously, and the influencing factors were analyzed.

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Objective: To evaluate the effect of schistosomiasis control in towns that had reached the criteria of infection controlled in Nanchang City.

Methods: The residents and livestock of 14 towns that had reached the criteria of infection controlled in Nanchang, Xinjian and Jinxian counties of Nanchang City were sampled to investigate the schistosomiasis endemic situation, Oncomelania hupensis snail status, and data of schistosomiasis control work.

Results: The positive rate of serum tests of the residents was 2.

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Article Synopsis
  • The study aimed to understand how the calcium cyanamide synthetic drug affects the morphology of Schistosoma japonicum eggs, with the goal of exploring the drug's mechanism against schistosome eggs.
  • Researchers mixed the drug with cattle feces containing the eggs and monitored changes over a week, comparing treated samples with blank controls.
  • Results showed that the treatment caused significant damage to the eggs, including color changes, atrophy of miracidia, and thickening of egg shells, with the effects worsening over time.
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Objective: To understand the endemic regulation of acute schistosomiasis in Nanchang City of Jiangxi Province from 2005 to 2012 so as to provide the reference for policy-making of schistosomiasis control.

Methods: The data of acute schistosomiasis were collected and analyzed with the descriptive epidemiology method in Nanchang City from 2005 to 2012.

Results: A total of 52 acute schistosomiasis cases were reported in Nanchang City from 2005 to 2012.

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Objective: To understand the dynamics of human infection and reinfection of Schistosoma japonicum after chemotherapy in marshland and lake endemic regions so as to provide the evidence for developing a cost-effective control strategy.

Methods: From 2007 to 2011, the schistosome infection, intensities and reinfection of population were investigated and the results were analyzed dynamically in Caohui Village, a national schistosomiasis surveillance site in Changyi Township, Xinjian County, Jiangxi Province, China.

Results: The schistosome infection rate was 3.

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Dechlorinated water (100 ml, 30 degrees C) was put into a plate (diameter 15 cm), and 1% niclosamide spreading oil 5 microl was added, then a ring of Schistosoma japonicum cercariae were picked up to the plate. The time of killing all the cercariae was observed at three time points (immediately, 24, 48 h), and the dechlorinated water was used as control. The results showed that schistosome cercariae were all killed in three minutes by 1% niclosamide spreading oil at the three time points.

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Objective: To explore the influencing factors of the significant decrease of snail densities in Poyang Lake region, Nanchang City, 2011.

Methods: According to the elevation of the environment, 5 grasslands where there were high snail densities and their elevations were from 14 to 17 m were selected as study areas. The data of snails in the past three years and the hydrological information in the past five years were collected and analyzed.

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Objective: To study an intervention model of "schools without infected students with schistosoma japonica", to control and prevent students from schistosoma infection.

Methods: Twelve primary schools of four heavy endemic counties (districts) with schistosomiasis in the Poyang Lake areas were selected as the study fields, of which, ten schools were the experimental groups, and the other two schools were the control groups by cluster random sampling. All enrolment students were the target population.

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Objective: To establish an intervention model of school health promotion, and apply it in developing "schistosomiasis-free schools".

Methods: At the pilot stage, all students of Henghu primary school and Banshan primary school in Xinjian County of Jiangxi Province were selected as experiment group and control group, respectively. A baseline survey covered knowledge and attitude on schistosomiasis control, water contact behaviors and Schistosoma japonicum infection rate.

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[The second stage larvae of Ascaris lumbricoides].

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi

August 2004

Objective: To induce the apoptosis of human alveolar epithelial cells (A549) by the extraction of the second stage larvae of Ascaris lumbricoides and investigate the extraction concentration and inducing time related to the apoptosis.

Methods: Following to the results of Microculture Tetrazolium Test (MTT), five concentrations of the extraction of the second stage larvae were chosen to induce the apoptosis of A549 cells. Meanwhile, control groups without the inducement were set up.

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