The Prognostic Value of Microvascular Density in Early Postoperative Recurrence and Metastasis of T1 Esophageal Squamous Cell Carcinoma.

Objective: To identify the relation of microvascular density (MVD) to the early postoperative recurrence and metastasis of T1 esophageal squamous cell carcinoma, and to determine whether MVD could be a prognostic predictor of esophageal squamous cell carcinoma.

Methods: Patients with T1 esophageal squamous cell carcinoma were enrolled. Immunohistochemistry with primary antibody against CD-34 was performed to count MVD.

Evaluation of a Spinosad Controlled-Release Formulation Based on Chitosan Carrier: Insecticidal Activity against (L.) Larvae and Dissipation Behavior in Soil.

Controlled-release pesticide formulations using natural polymers as carriers are highly desirable owing to their good biocompatibility, biodegradability, and improved pesticide utilization. In this study, the application potential of our previously prepared spinosad/chitosan controlled-release suspension (SCCS) was evaluated through both toxicity and dissipation tests. A comparison with the spinosad suspension concentrate and the commercial spinosad emulsion in water showed that the insecticidal activity of SCCS against larvae displayed the best quick-acting performance as well as long-term efficacy of more than 20 days.

Coprecipitation-based synchronous pesticide encapsulation with chitosan for controlled spinosad release.

Controlled release pesticide formulation with long-term efficacy is highly desirable for improving pesticide utilization and reducing adverse effects. In this study, an environment-friendly controlled release formulation of biological insecticide spinosad was fabricated through the coprecipitation-based synchronous encapsulation with chitosan. The resulted spinosad/chitosan formulation showed an excellent encapsulation efficiency of 60 %, obvious pH and temperature sensitivity, and outstanding ultraviolet shielding ability.

Muscle-bone crosstalk and potential therapies for sarco-osteoporosis.

The nature of muscle-bone crosstalk has been historically considered to be only mechanical, where the muscle is the load applier while bone provides the attachment sites. However, this dogma has been challenged with the emerging notion that bone and muscle act as secretory endocrine organs affect the function of each other. Biochemical crosstalk occurs through myokines such as myostatin, irisin, interleukin (IL)-6, IL-7, IL-15, insulin-like growth factor-1, fibroblast growth factor (FGF)-2, and β-aminoisobutyric acid and through bone-derived factors including FGF23, prostaglandin E , transforming growth factor β, osteocalcin, and sclerostin.

[Surface characteristics of alkali modified activated carbon and the adsorption capacity of methane].

Coconut shell based activated carbon was modified by alkali with different concentrations. The surface structures of tested carbons were observed and analyzed by SEM and BET methods. Boehm's titration and SEM/EDS methods were applied to assay the functional groups and elements on the carbon surface.

Zebrafish krüppel-like factor 4a represses intestinal cell proliferation and promotes differentiation of intestinal cell lineages.

Background: Mouse krüppel-like factor 4 (Klf4) is a zinc finger-containing transcription factor required for terminal differentiation of goblet cells in the colon. However, studies using either Klf4(-/-) mice or mice with conditionally deleted Klf4 in their gastric epithelia showed different results in the role of Klf4 in epithelial cell proliferation. We used zebrafish as a model organism to gain further understanding of the role of Klf4 in the intestinal cell proliferation and differentiation.

[Clinical analysis of 60 thyroglossal tract cyst cases].

Objective: To study the characteristics of thyroglossal tract cyst epidemiology and summarize how to improve the operation therapeutic effect.

Methods: The clinic appearance, the pathological characteristics and the therapeutic effect of the 60 thyroglossal tract cyst cases were analyzed.

Results: Thyroglossal tract cyst mostly occurred in children and teenagers.