Association of underweight and obesity with adverse postoperative renal outcomes in infants and young children undergoing congenital heart surgery.

Postoperative acute kidney injury (AKI) is a prevalent condition and associated with increased morbidity and mortality following cardiac surgery. This study aimed to investigate the association of underweight and obesity with adverse postoperative renal outcomes in infants and young children undergoing congenital heart surgery. This retrospective cohort study included patients aged from 1 month to 5 years who underwent congenital heart surgery with cardiopulmonary bypass at the Second Xiangya Hospital of Central South University from January 2016 to March 2022.

Machine Learning-Based Prediction of Acute Kidney Injury Following Pediatric Cardiac Surgery: Model Development and Validation Study.

Background: Cardiac surgery-associated acute kidney injury (CSA-AKI) is a major complication following pediatric cardiac surgery, which is associated with increased morbidity and mortality. The early prediction of CSA-AKI before and immediately after surgery could significantly improve the implementation of preventive and therapeutic strategies during the perioperative periods. However, there is limited clinical information on how to identify pediatric patients at high risk of CSA-AKI.

A Rare Case of Cardiac Metastatic Uterine Intravenous Leiomyomatosis.

Intravenous leiomyomatosis (IVL) is a distinct uterine leiomyoma, even rare when combined with intracardiac invasion. Although leiomyomas are histologically benign, intracardiac metastasis may cause circulatory failure and death. Herein, we report a 55-year-old woman with a tricuspid chordae mass on echocardiography.

polymorphisms associated with warfarin stable dose in Chinese patients: a stepwise conditional analysis.

The aim of this study was to investigate whether variability in warfarin stable dose (WSD) could be influenced by vitamin K-related polymorphisms in patients with heart valve replacement. Twenty-nine vitamin K-related SNPs in 208 patients who initially took warfarin and achieved WSD were genotyped. After conducting conditional analysis for both -1639G>A and *3, rs1800139 and rs1800154 were significantly associated with WSD (p = 0.

LRP1 and APOA1 Polymorphisms: Impact on Warfarin International Normalized Ratio-Related Phenotypes.

Warfarin international normalized ratio (INR)-related phenotypes such as the percentage of INR time in the therapeutic range (PTTR) and INR variability are associated with warfarin adverse reactions. However, INR-related phenotypes greatly vary among patients, and the underlying mechanism remains unclear. As a key cofactor for coagulation proteins, vitamin K can affect warfarin INR values.

Cytochrome P450 oxidoreductase genetic polymorphisms A503V and rs2868177 do not significantly affect warfarin stable dosage in Han-Chinese patients with mechanical heart valve replacement.

Purpose: To investigate the influence of cytochrome P450 oxidoreductase (POR) polymorphisms (A503V and rs2868177) on warfarin stable dosage (WSD) in Han-Chinese patients with mechanical heart valve replacement (MHVR).

Methods: Three hundred and seventeen Han-Chinese MHVR patients on stable maintenance dose of warfarin were enrolled. Blood samples were collected for genotyping analyses of VKORC1 -1639G>A, CYP2C9 *3, CYP4F2 rs2108622 and POR (A503V and rs2868177).

[Estimation of vegetation coverage based on an improved sub-pixel model].

Vegetation coverage is an important parameter in terrestrial ecological process, meteorological, and climatic models. By eliminating the errors from the precision of image classification and the noises of remote sensing images, and by using the actual data from fieldwork, this paper determined the maximum and minimum values of normalized difference vegetation index (NDVI), improved the sub-pixel model, and verified this model by calculating the vegetation coverage of Beijing. The results showed that the estimation value of the improved model was very close to the measurements, especially for the herbaceous plants whose vegetation types were the same but the densities were different.

[Experience in treatment of Eisenmenger's syndrome by heart-lung transplantation].

Objective: To summarize the experience in treatment of Eisenmenger's syndrome by heart-lung transplantation (HLT).

Methods: Two cases of congenital heart disease with Eisenmenger's syndrome, aged 20 and 22, underwent bicaval orthotopic HLT. Modified St.

[Surgical treatment of 92 cases of thoracic aortic aneurysms].

Objective: To explore the timing of surgical treatment of thoracic aortic aneurysms.

Methods: The clinical data of 92 patients with thoracic aortic aneurysm who underwent surgical treatment in our department during the latest 10 years were retrospectively reviewed.

Results: The overall operative mortality was 13.