Publications by authors named "Guo-Xin He"
Article Synopsis
- The study investigated how heat stress (HS) affects the expression of interleukin-1β (IL-1β) and IL-18 in BV-2 microglial cells, focusing on the role of glutamate transmission.
- BV-2 cells were exposed to heat stress at 40°C and evaluated for glutamate release and the expression of related receptors and proteins, with some cells treated with glutamate or antagonists to study their effects.
- Results showed that HS increased glutamate levels and proinflammatory factors IL-1β and IL-18, but preincubation with specific drugs reduced these effects, suggesting microglia play a role in glutamate metabolism during heat stress.
Background: Quetiapine, known as a non-classical antipsychotic drug, is frequently used for the treatment of mental diseases, such as schizophrenia, bipolar disorder, and major depressive disorder. Acute lung injury, a rarely reported side effect of quetiapine, is described in this case report.
Case Summary: Due to terminal delirium, a 66-year-old man took a large dose of quetiapine and then developed severe pulmonary disease.
Background: Xpert Bladder Cancer is a detection method developed in recent years, designed with the functions of integrating sample automatically, nucleic acid amplification, and target sequence detection. It is a urine assay targeting five mRNAs (CRH, IGF2, UPK1B, ANXA10, and ABL1). The purpose of this article is to review the accuracy of Xpert Bladder Cancer in the follow-up diagnosis of bladder cancer and evaluate the role of Xpert Bladder Cancer in detecting the recurrence of non-muscle-invasive bladder cancer in the round.
View Article and Find Full Text PDFBackground: Rat bite fever (RBF), a severe infectious disease, can result from transmission of the pathogen Streptobacillus moniliformis (S. moniliformis) by rat bite. RBF diagnosis can be overlooked.
View Article and Find Full Text PDF[Antagonizing effect of diazepam on fipronil induced acute poisoning].
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
January 2007
[An experimental study on acute poisoning by fipronil in mice and its pharmaceutical therapy].
Zhonghua Yu Fang Yi Xue Za Zhi
May 2006
Objective: To investigate the toxicity of fipronil in mice and the therapeutic effects of diazepam and phenobarbital sodium.
Methods: Mice were administered by gastric tube with fipronil at six doses and their behavioral changes, pathological changes in their major viscera under light and electron microscopy and deaths were observed after acute poisoning. Distribution and quantity of nerve cells positive in glutamic acid (Glu) or gamma-aminobutyric acid (gamma-GABA) in the brain of mice were detected by immunohistochemical methods and micro-image analysis.