Publications by authors named "Guo-Sheng Wan"
Two new isoxazolines from the husks of Xanthoceras sorbifolia Bunge.
J Asian Nat Prod Res
August 2016
Two new isoxazoline compounds, 1-oxa-2-azaspiro[4.5]dec-2-ene-8β-ol (1) and 1-oxa-2-azaspiro[4.5]dec-2-ene-8α-ol (2), were isolated from the husks of fruits of Xanthoceras sorbifolia Bunge and their structures were determined by spectroscopic analyses, including X-ray crystallography, HRESI-MS, UV, IR, and 1D and 2D NMR (HSQC, HMBC, NOESY) methods.
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- The study aimed to analyze the healthcare access and insurance status for hypertensive patients in urban and rural areas across five provinces in China in 2010, focusing on community health management.
- Researchers selected cities and counties based on economic conditions and surveyed 8326 hypertensive patients, finding significant urban-rural differences in medical diagnosis and follow-up care.
- Key findings revealed urban patients primarily diagnosed at hospitals, while rural patients frequented village clinics; convenience and low costs were major factors influencing their healthcare choices.
The methanol extract from roots of Salacia hainanensis Chun et How afforded three new compounds, 24,26-dihydroxy-25-methoxy-tirucall-9-en-3-one (1), 2β,3β,22α-trihydroxy-lup-20(29)-ene (2) and 3β-hydroxy-2-carbonyl-lupan-29-oic acid (3), along with six known triterpenoids (4-9). Their structures were established on the basis of spectral analysis, in particular according to the data obtained by two-dimensional-NMR and high-resolution mass spectra experiments. Some of them showed much stronger inhibitory activity towards α-glucosidase than the positive control (acarbose, IC₅₀ 10.
View Article and Find Full Text PDF[The analysis of drug cost and direct medical expense in community health management of hypertensive patients].
Zhonghua Yu Fang Yi Xue Za Zhi
August 2011
Objective: To investigate the current situation of drug cost, hospitalization cost and direct medical expense in community health management of hypertensive patients, in order to lay foundation for evaluating whether the community health management in basic public health service has cost-effect in Health Economics.
Methods: A total of 8326 hypertensive patients from 10 survey pilots in 5 provinces were selected by cluster sampling methods, including 3967 patients who took part in community health management for over 1 year as management group and 4359 cases who have never taken part in community health management as control group. The essential information of research objects were collected by questionnaire; and the medical cost information in the last year (from November 2009 to November 2010) were collected retrospectively.