Objective: To understand the involvement of the mGluR5-mediated JNK signaling pathway in rats with diabetic retinopathy (DR).
Methods: This study established rat models of diabetes mellitus (DM), which were divided into Normal, DM, DM + CHPG (mGluR5 agonist CHPG), and DM + MTEP (mGluR5 antagonist MTEP) groups. The blood glucose and weight of rats were recorded.