Descriptions of the last instar larvae of Anotogaster chaoi Zhou, 1998 and Neallogaster annandalei (Fraser, 1923) from Erhai Lake Basin, Yunnan, China (Odonata: Cordulegastrids).

The exuviae of Anotogaster chaoi Zhou, 1998 and Neallogaster annandalei (Fraser, 1923) are described and illustrated for the first time from Erhai Lake Basin, Yunnan Province, China, based on the final stage larvae reared in a laboratory. Diagnostic differences between the larvae of congeneric A. chaoi, A.

The roles of liquidity and delay in financial markets based on an optimal forecasting model.

We investigate the roles of liquidity and delay in financial markets through our proposed optimal forecasting model. The efficiency and liquidity of the financial market are examined using stochastic models that incorporate information delay. Based on machine learning, we estimate the in-sample and out-of-sample forecasting price performances of the six proposed methods using the likelihood function and Bayesian methods, and the out-of-sample prediction performance is compared with the benchmark model ARIMA-GARCH.

First description of the larva of Archineura incarnata (Karsch, 1891) with notes on the biology (Odonata: Calopterygidae).

The final instar larva of the genus Archineura Kirby, 1894 is described for the first time, based on a specimen of the Chinese endemic species Archineura incarnata (Karsch, 1892) collected from Mt. Nankunshan, Guangdong Province, China. The larva is distinguished by several characters, including its moderately slender build combined with the distinctive extremely long legs, long, narrow, uniquely spined outer caudal appendages, a mask strongly expanded anteriorly with a relatively small median cleft, and robust spines at the apex of the labial palp.

Asymmetric synthesis of N-N axially chiral compounds organocatalytic atroposelective -acylation.

Compared with the well-developed C-C and C-N axial chirality, the asymmetric synthesis of N-N axial chirality remains elusive and challenging. Herein we report the first atroposelective -acylation reaction of quinazolinone type benzamides with cinnamic anhydrides for the direct catalytic synthesis of optically active atropisomeric quinazolinone derivatives. This reaction features mild conditions and a broad substrate scope and produces N-N axially chiral compounds with high yields and very good enantioselectivities.

[Bidirectional regulation of acupuncture: a subgroup analysis of multicenter randomized controlled trial of acupuncture with for irritable bowel syndrome].

Objective: To explore the bidirectional regulation of acupuncture based on a subgroup analysis of multicenter randomized controlled trial of acupuncture with for irritable bowel syndrome (IBS).

Methods: A total of 519 patients were included in the analysis, including 137 patients with constipation type irritable bowel syndrome (IBS-C) (92 cases in the acupuncture group and 45 cases in the polyethylene glycol [PEG] group), and 382 patients with diarrhea type irritable bowel syndrome (IBS-D) (252 cases in the acupuncture group and 130 cases in the pinaverium group). The patients in the acupuncture group were given acupuncture at Baihui (GV 20), Yintang (GV 29), Tianshu (ST 25), Shangjuxu (ST 37), Zusanli (ST 36), Sanyinjiao (SP 6) and Taichong (LR 3) once every other day, 3 times a week.

[Correlation between curative effect and 5-HTTLPR polymorphism in treatment of diarrhea-predominant irritable bowel syndrome with acupuncture for regulating and strengthening spleen].

Objective: To compare the curative effect on diarrhea-predominant irritable bowel syndrome (IBS-D) between acupuncture for regulating and strengthening spleen and pinaverium bromide, and explore the relevant mechanism of curative effect of acupuncture in view of polymorphism of 5-hydroxytryptamine transporter gene-linked polymorphic region (5-HTTLPR).

Methods: A total of 231 patients with IBS-D were randomized into an acupuncture group (154 cases) and a western medication group (77 cases) at the ratio of 2 to 1. In the acupuncture group, acupuncture was applied to acupoint regimen for regulating and strengthening spleen, i.

Descriptions of larvae of Caliphaea angka Hämäläinen, 2003 and Mnais gregoryi Fraser, 1924 (Odonata: Calopterygidae).

The larvae of Caliphaea angka Hämäläinen, 2003 and Mnais gregoryi Fraser, 1924 are described and illustrated for the first time from Erhai lake Basin, Yunnan Province, China. Notes on their habitat are provided. This paper represents the first verified description of the larva of Caliphaea Hagen in Selys, 1859.

Clinical significance of cellular immunity function and inflammatory factors assays in alveolar lavage fluid for severe COVID-19 pneumonia.

In this study, we aimed to investigate the changes of lymphocyte subsets (CD3 , CD4 , CD8 ) and inflammatory factors (interleukin-6 [IL-6], hypersensitive C-reactive protein [HS-CRP], and procalcitonin [PCT]) of alveolar lavage fluid in patients with severe corona virus-2019 (COVID-19) pneumonia and their clinical impact on the assessment of disease severity and prognosis. Twenty-four patients with severe COVID-19 pneumonia were admitted to the intensive care unit (ICU) of the Ezhou Central Hospital from February 1 to March 22, 2020. According to the 28-day prognosis, they were assigned to a death group and a survival group.

[Establishment of An Improved Rat Model of Sepsis Induced by Cecal Ligation and Puncture].

To establish an improved animal model of sepsis induced by cecal ligation and puncture(CLP). Ninety-six male Sprague-Dawley rats were randomly divided into sham operation group(=24),intubation group(=24),CLP group(=24),and CLP+intubation group(=24).The mortality rate,abdominal cavity condition,pathological changes and pathological scores of heart,lungs,liver,and kidneys of rats in each group were observed after modeling.

Asymmetric Cycloaddition of ortho-Hydroxyphenyl-Substituted para-Quinone Methides and Enamides Catalyzed by Chiral Phosphoric Acid.

A BINOL-based chiral phosphoric acid was employed as an efficient catalyst in enantioselective cycloaddition of ortho-hydroxyphenyl-substituted para-quinone methides and enamides, which gave rise to acetamido-substituted tetrahydroxanthenes with three adjacent stereogenic centers in high yields (up to 99%) and excellent stereoselectivities (up to >99:1 diastereomeric ratio and up to 98% ee).

Access to P-chiral phosphine oxides by enantioselective allylic alkylation of bisphenols.

A novel biscinchona alkaloid-catalyzed highly enantioselective desymmetrization reaction of bisphenol compounds with achiral Morita-Baylis-Hillman carbonate agents was developed. Through the asymmetric allylic alkylation strategy, a broad range of optically active P-stereogenic phosphine oxides were generated with excellent to good yields (up to 99%) and high enantioselectivities (up to 98.5 : 1.

Anacardic acid suppresses fibroblast-like synoviocyte proliferation and invasion and ameliorates collagen-induced arthritis in a mouse model.

Anacardic acid, which is abundant in nutshell of Anacardium occidentale, has multiple pharmacological activities. In this study, we examined the therapeutic potential of anacardic acid in treating rheumatoid arthritis (RA). We explored the effects of anacardic acid on collagen-induced arthritis (CIA) in mice and on the proliferation and invasion of RA fibroblast-like synoviocytes (RA-FLSs).

Chirality Sensing of α-Hydroxyphosphonates by N-tert-Butyl Sulfinyl Squaramide.

N-tert-Butyl sulfinyl squaramides were used for chiral discrimination of α-hydroxyphosphonates using P NMR. A free energy relationship study indicates that both steric and the electronic effects influence the chiral recognition of the donors.

N-tert-Butyl Sulfinyl Squaramide Receptors for Anion Recognition through Assisted tert-Butyl C-H Hydrogen Bonding.

A series of novel N-tert-butyl sulfinyl squaramide receptors have been designed and synthesized. Their interactions with a range of inorganic anions were studied in solution by H NMR spectroscopy. This new type of squaramide displayed better anion-binding abilities over conventional diphenyl squaramides.

A new species of Lamelligomphus Fraser, 1922 (Odonata: Gomphidae) from southern Yunnan, China.

Lamelligomphus annakarlorum sp. nov. is described based on specimens collected from southern Yunnan Province, China (holotype male: Xishuangbanna National Nature Reserve, 21°57'59''N, 101°12'37''E, Xishuangbanna Dai Autonomous Prefecture, Yunnan Province, China).

Direct measurement of nonlocal entanglement of two-qubit spin quantum states.

We propose efficient schemes of direct concurrence measurement for two-qubit spin and photon-polarization entangled states via the interaction between single-photon pulses and nitrogen-vacancy (NV) centers in diamond embedded in optical microcavities. For different entangled-state types, diversified quantum devices and operations are designed accordingly. The initial unknown entangled states are possessed by two spatially separated participants, and nonlocal spin (polarization) entanglement can be measured with the aid of detection probabilities of photon (NV center) states.

Albumin Supplement Affects the Metabolism and Metabolism-Related Drug-Drug Interaction of Fenoprofen Enantiomers.

The influence of albumin towards the metabolism behavior of fenoprofen enantiomers and relevant drug-drug interaction was investigated in the present study. The metabolic behavior of fenoprofen enantiomers was compared in a phase II metabolic incubation system with and without bovine serum albumin (BSA). BSA supplement increased the binding affinity parameter (Km) of (R)-fenoprofen towards human liver microsomes (HLMs) from 148.

CA72-4 combined with CEA, CA125 and CAl9-9 improves the sensitivity for the early diagnosis of gastric cancer.

Background/aims: To determine whether the combination of tumor markers (CA72-4, CA125, CA19-9 and CEA) could increase the sensitivity and accuracy for in the diagnosis of gastric cancer (GC).

Methods: This study is a retrospective analysis. A total of 426 patients, including 106 patients with GC, 149 patients with benign gastric diseases and 171 healthy people, who visited Zhejiang Xiaoshan Hospital from January 2011 to December 2013, were measured by serum markers, including CA72-4, CA125, CA19-9 and CEA.

Description of Atrocalopteryx fasciata spec. nov. from Yunnan, China (Odonata: Calopterygidae).

Atrocalopteryx fasciata Yang, Hämäläinen & Zhang, spec. nov. (holotype ♂, from China, Yunnan, Dehong, Yingjiang, deposited at Odonata Collection of College of Agriculture and Life Sciences, Dali University, Dali, Yunnan, China) is described and illustrated from the male sex.

Effects of H(2)O(2), paraquat, and ethephon on herbal drug quality of Schiandra chinensis based on reactive oxygen species system.

Background: Nowadays, more and more herbal drugs of traditional Chinese medicine (TCM) rely on cultivation rather than natural resources because of overexploitation, and the study on quality of cultivated herbal medicines has become a hotspot in the research field of ecology of TCM resources. Though some of molecular biology techniques could improve the contents of secondary metabolites, those chemical compositions may differ from what we require from natural products, resulting in different treatment efficacy.

Objective: To explore ways and means of improving TCM quality by means of regulating secondary metabolism from the perspective of natural physiological ecology.

[The value of assay of (1, 3)-β-D-glucan in bronchoalveolar lavage fluid for detection of invasive pulmonary fungal infection in critically ill patients in intensive care unit].

Objective: To evaluate the value of (1, 3)-β-D-glucan (G test) in bronchoalveolar lavage fluid (BALF) in diagnosing and determining the therapeutic effects among the critically ill patients suspected with invasive pulmonary fungal infection (IPFI).

Methods: Study was conducted between February 2010 and August 2011 in medical intensive care unit (MICU) of the Affiliated Hospital of Guiyang Medical College. Patients suspected of suffering from IPFI were enrolled.

[Effects of high positive end-expiratory pressure combined with recruitment maneuvers in patients with acute respiratory distress syndrome].

Objective: To investigate the clinical effects and safety degree of high positive end-expiratory pressure (PEEP) combined with lung recruitment maneuver (RM) in patients with acute respiratory distress syndrome (ARDS).

Methods: Thirty-eight patients in medical intensive care unit (MICU) of Affiliated Hospital of Guiyang Medical College suffering from ARDS admitted from June 2008 to May 2010 were enrolled in the study. With the envelope method they were randomized into RM group and non-RM group, with n=19 in each group.

A modified technique of bone grafting pedicled with femoral quadratus for alcohol-induced osteonecrosis of the femoral head.

Background: Quadratus femoris pedicled bone grafting has yielded satisfactory long-term clinical outcome for osteonecrosis of the femoral head (ONFH) in pre-collapse ONFH without extensive lesion. However, for pre-collapse ONFH with extensive necrotic area, it is still challenging to preserve the femoral head. The current study aimed to introduce a new technique of deliquesce strut with titanium mesh containing bone grafting pedicled with the femoral quadratus and to evaluate its short-term outcomes.

[The monitoring and its clinical significance of the hydrogen peroxide and interleukin-6 levels in exhaled breath condensate of chronic obstructive pulmonary diseases patients undergoing mechanical ventilation].

Objective: To explore the relationship of inflammatory response of the respiratory tract and prognosis of chronic obstructive pulmonary diseases (COPD) patients undergoing mechanical ventilation (MV) in respiratory intensive care unit (RICU).

Methods: Thirty patients with COPD undergoing MV were involved in the study, and divided into survival group (n=16) and non-survival group (n=14). Exhaled breath condensate (EBC) was collected on day 1, 3, 5, 7 after MV.