Publications by authors named "Guo-Hong Sheng"

Background: Recurrence is the major challenge facing endoscopic submucosal dissection (ESD)-based treatment therapies for early gastric cancer (EGC). Urgent development of simple and easy surveillance approaches will enhance clinical treatment of the disease.

Aim: To explore the role of computed tomography (CT) recurrence in evaluating EGC after ESD treatment.

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Article Synopsis
  • Cardiac dysfunction, which is a problem with how the heart works, can happen during a condition called endotoxemia, and a specific enzyme called PFKFB3 seems to be involved in this issue.
  • Researchers did experiments on mice to see how PFKFB3 affects heart damage caused by an injection of a substance called LPS, and they found that blocking PFKFB3 helped protect the heart.
  • The study shows that by stopping PFKFB3, not only did the heart function improve, but it also reduced harmful inflammation and cell death in the heart cells during this sickness.
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Levofloxacin is an emerging pollutant. Single levofloxacin and TiO2 have no visible-light activity. However, photodegradation of levofloxacin dramatically enhanced in the presence of TiO2 under visible light irradiation.

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A convenient method for the stereoselective syntheses of beta-amino acids with alpha-substitutions has been developed. This synthetic route involves the preparation of isoxazolidinones through hydroxylamine addition to unsaturated esters and subsequent hydrogenation. This procedure is also useful for the stereoselective syntheses of alpha-deuterated beta-amino acids.

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