Anti-inflammatory principles from Lindera aggregata.

Four new sesquiterpenes (1-4), one new alkaloid (5), and one new benzenoid glycoside (6) were characterized from Lindera aggregata, and their structures were elucidated according to their spectrometric analytical data. Among these isolates, 3 and 4 were constructed as possessing unprecedented carbon skeletons from the natural source. Some of these purified constituents were examined for their anti-inflammatory bioactivity.

New Benzenoids from the Roots of Lindera aggregata.

Two new benzenoids, linderagatin A and B (1-2), were isolated from the roots of Lindera aggregata. Their structures were elucidated on the basis of 1D (1H, 13C) and 2D NMR (COSY, NOESY, HSQC and HMBC) spectra. Moreover, their absolute configurations were established from ECD spectra compared with previous reports.