Publications by authors named "Guo-Fang Feng"
Evaluation of lipoprotein-associated phospholipase A2 in healthy Chinese Han adult serum.
Lipids Health Dis
January 2014
Objective: The aim of this study is to establish lipoprotein-associated phospholipase A2 (Lp-PLA2) reference intervals (RIs) in healthy Chinese Han adults as a clinical diagnostic indicator according to the Clinical and Laboratory Standards Institute (CLSI) C28-A3 guidelines.
Design And Methods: Lp-PLA2 levels in 763 healthy Chinese Han subjects (392 males and 371 females) were determined by colorimetric analysis and the central 95th percentile RIs were determined using non-parametric statistical methods. The correlations between serum Lp-PLA2 and blood markers were analyzed by Spearman correlation analyses.
Article Synopsis
- * Semen and blood samples were collected, and mtDNA haplogroups were identified through DNA sequencing techniques, particularly focusing on hypervariable segments and specific genetic markers.
- * Results indicated that having the mtDNA haplogroup R significantly improves sperm motility, reducing the likelihood of asthenozoospermia by approximately 2.97 times compared to individuals without this haplogroup.
Article Synopsis
- The bacterial pathogen Xanthomonas campestris pv. campestris activates disease symptoms through hrp genes, specifically group II hrp genes, regulated by a transcriptional regulator influenced by a two-component system (TCS).
- Evidence has identified XC_3670 as a TCS sensor kinase (HpaS), whose mutation severely reduces hypersensitive response (HR) and virulence.
- HpaS interacts with the TCS response regulator HrpG, while HpaR2, another response regulator near hpaS, is necessary for virulence but not HR, indicating potential TCS interactions between HpaS, HrpG, and HpaR2.