Publications by authors named "Guo-Fan Wang"

Aim: Myeloperoxidase (MPO) and glutathione S-transferase pi 1 (GSTP1) are important carcinogen-metabolizing enzymes. The aim of this study was to investigate the association between the common polymorphisms of MPO and GSTP1 genes and lung cancer risk in Chinese Han population.

Methods: A total of 266 subjects with lung cancer and 307 controls without personal history of the disease were recruited in this case control study.

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Calcium (Ca(2+)) signals are involved in important checkpoints in cell death pathways and promote both apoptosis and autophagy. However, the relationship between autophagy and apoptosis in response to Ca(2+) level elevation is poorly understood. Here, we provided evidence that the influx of extracellular Ca(2+) triggered by Trichokonin VI (TK VI), an antimicrobial peptide, induced calpain-dependent apoptosis and autophagy in hepatocellular carcinoma (HCC) cells.

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Oyster extracts have been reported to have many bioactive peptides. But the function of oyster peptides produced by proteolysis is still unknown. In this study, the oligopeptide-enriched hydrolysates from oyster (Crassostrea gigas) were produced using the protease from Bacillus sp.

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Article Synopsis
  • The study aimed to analyze the effects of preserving the vagus nerve and reconstructing the gastric fundus during esophagectomy and cardiectomy in patients with esophageal and cardiac cancer.
  • It compared two groups of 68 patients each: one with vagus nerve preservation (VPRG) and gastric reconstruction, and the other with severed vagus nerve and no reconstruction (VSNG).
  • Results showed that VPRG patients experienced fewer digestive symptoms post-surgery and maintained stable gastric function metrics, although they had a higher incidence of postoperative complications like atrophic gastritis compared to the VSNG group.
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Objective: To evaluate the indications and surgical procedure of bronchial and pulmonary artery sleeve resection for patients with centrally located non-small cell lung cancer, and how to prevent complications.

Methods: From July 1989 to Aug 2000, 32 cases of central NSCLC were treated with bronchial and pulmonary arterial sleeve resection and reconstruction. The results were retrospectively analyzed.

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