[Retracted] IQGAP1‑siRNA inhibits proliferation and metastasis of U251 and U373 glioma cell lines.

Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the GAPDH control western blotting data shown in Fig. 1C, and other western blotting data included in Figs. 2D and 7C and D, were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes.

The role of galectin-3 in the tumorigenesis and progression of pituitary tumors.

Galectin-3 (Gal-3), a β-galactoside-binding protein, has been implicated in cell proliferation, cell adhesion, and the progression and metastasis of various types of cancer. The present study investigated the involvement of Gal-3 in the tumorigenesis and progression of pituitary tumors using three rat pituitary tumor cell lines. Following transfection with Gal-3 expression and interference vectors, the impact of Gal-3 on proliferation, apoptosis and migration of pituitary tumor cells was been investigated.

Expression and functional analysis of TCF4 isoforms in human glioma cells.

Transcription factor 4 (TCF4) is a member of the T-cell factor/lymphoid enhancer factor (TCF/LEF) transcription factor family in the Wnt/β‑catenin signaling pathway. The alternative splicing of TCF4 has been reported to exhibit potential carcinogenic properties in various cancer types. In the present study, TCF4 isoforms were cloned and identified in three human glioma cell lines, with the majority of splicing regions being exons 4, 5, 14, 15, and 16.

Treatment strategies for traumatic cervico-cranial pseudoaneurysms: A single institution experience.

Aim: Limited clinical and angiographic data exists for patients with traumatic cervico-cerebral pseudoaneurysms. In this paper, we present our limited experience with various management strategies for traumatic cervico-cranial pseudoaneurysms.

Materials And Methods: We retrospectively analyzed 37 consecutive cases of traumatic pseudoaneurysms involving the cervico-cranial or the cerebral arteries diagnosed at our center from September 2009 to December 2014.

IQGAP1‑siRNA inhibits proliferation and metastasis of U251 and U373 glioma cell lines.

IQ motif containing GTPase activating protein 1 (IQGAP1) is a scaffold protein, which is aberrantly expressed in several tumor types and is closely associated with the development, metastasis and prognosis of cancer. Several studies have demonstrated that IQGAP1 has broad prospects in the basic and clinical research of tumors. The present study aimed to explore the effects of IQGAP1‑small interfering (si) NA on the proliferation and metastasis of U251 and U373 glioma cell lines, which markedly expressed IQGAP1.

Correlation between VEGFR2 rs2071559 polymorphism and glioma risk among Chinese population.

Objective: We investigated the correlation between vascular endothelial growth factor 2 (VEGFR2) polymorphism and glioma risk among Chinese population.

Method: Case-control study design was adopted, and blood samples and clinical data of 250 glioma cases and 260 control subjects were collected. Epidemiological questionnaire survey was performed, and DNA extraction, concentration normalization and packaging were carried out using Qiagen Blood Kit.

Docosahexaenoic acid inhibits mechanical allodynia and thermal hyperalgesia in diabetic rats by decreasing the excitability of DRG neurons.

Diabetes mellitus is a common metabolic disease in human beings with characteristic symptoms of hyperglycemia, chronic inflammation and insulin resistance. One of the most common complications of early-onset diabetes mellitus is peripheral diabetic neuropathy, which is manifested either by loss of nociception or by allodynia and hyperalgesia. Dietary fatty acids, especially polyunsaturated fatty acids, have been shown the potential of anti-inflammation and modulating neuron excitability.

High Serum MiR-130a Levels Are Associated with Severe Perihematomal Edema and Predict Adverse Outcome in Acute ICH.

The development and/or progression of perihematomal edema (PHE) in patients with acute spontaneous intracerebral hemorrhage (ICH) vary substantially with different individuals. Although hematoma volume is a useful indicator for predicting PHE, its predictive power was not good at the early stage of ICH. Better predictors are urgently needed.

Blocking TRPV1 in nucleus accumbens inhibits persistent morphine conditioned place preference expression in rats.

The function of TRPV1 (transient receptor potential vanilloid subfamily, member 1) in the central nervous system is gradually elucidated. It has been recently proved to be expressed in nucleus accumbens (NAc), a region playing an essential role in mediating opioid craving and taking behaviors. Based on the general role of TRPV1 antagonist in blocking neural over-excitability by both pre- and post-synaptic mechanisms, TRPV1 antagonist capsazepine (CPZ) was tested for its ability to prohibit persistent opioid craving in rats.

Spontaneous arteriovenous fistula of the superficial temporal artery: Diagnosis and treatment.

Objectives: Despite the increasing reports of traumatic and iatrogenic arteriovenous fistulas (AVFs) of the superficial temporal artery (STA), the spontaneous origination of fistulas is extremely rare, and very little is known about their natural development. Spontaneous AVFs of the STA have the characteristic findings of an expanding, painless pulsatile mass and a palpable thrill with or without a vascular murmur.

Patients And Methods: This article describes five patients with AVFs of the STA with no history of a head injury.

Analysis of regulatory networks constructed based on gene coexpression in pituitary adenoma.

Gene coexpression patterns can reveal gene collections with functional consistency. This study systematically constructs regulatory networks for pituitary tumours by integrating gene coexpression, transcriptional and posttranscriptional regulation. Through network analysis, we elaborate the incidence mechanism of pituitary adenoma.

Beneficial impact of early cranioplasty in patients with decompressive craniectomy: evidence from transcranial Doppler ultrasonography.

Background: A cranioplasty (CP) is often performed after decompressive craniectomy (DC) for cosmetic and protective reasons; however, the timing of CP needs to be better evaluated to maximize beneficial outcomes and neurological recovery.

Objective: We investigated the effects and mechanisms of early CP compared to late CP on neurological recovery, from the perspective of cerebral blood flow (CBF).

Methods: This study retrospectively reviewed 43 patients undergoing early (<12 weeks) or late (≥ 12 weeks) cranioplasty after DC.

Functional network analysis with the subcellular location and gene ontology information in human allergic asthma.

Asthma is a chronic inflammatory disease characterized by airway hyperresponsiveness, tissue remodeling, and airflow obstruction. The pathogenesis of asthma is only partly understood, and there is an urgent need for improved therapeutic strategies for this disease. The protein-protein interaction (PPI) network has considerable promise as a tool for discovery of novel asthma therapeutic targets and their relationship.

Network asymmetry of motor areas revealed by resting-state functional magnetic resonance imaging.

There are ample functional magnetic resonance imaging (fMRI) studies on functional brain asymmetries, and the asymmetry of cerebral network in the resting state may be crucial to brain function organization. In this paper, a unified schema of voxel-wise functional connectivity and asymmetry analysis was presented and the network asymmetry of motor areas was studied. Twelve healthy male subjects with mean age 29.

Clinical and radiological observation in a surgical series of 36 cases of fibrous dysplasia of the skull.

Objectives: To describe the clinical and radiological findings in a consecutive series of patients diagnosed with fibrous dysplasia of the skull.

Patients And Methods: A retrospective analysis of collected data for 36 patients with histopathologically confirmed fibrous dysplasia involving the skull is presented. The demographic data, clinical presentation, radiographic characteristics, and the management of these patients were reviewed.

Enhancement of axonal regeneration of retinal ganglion cells in adult rats by etomidate: involvement of protein kinase C.

Purpose: To investigate the effect of etomidate (ET) on axonal regeneration of retinal ganglion cells (RGCs) in adult rats.

Methods: The optic nerve was transected intraorbitally at 1 mm from the optic disc, and an autologous peripheral nerve was transplanted onto the ocular ON stump in adult rats. Then the animals were treated with ET, Gö6976, ET combined with Gö6976, phorbol-12-myristate-13-acetate (PMA), or ET combined with PMA.

[Effect of renal artery embolization using 2-poly-hydroxyethyl-methacrylate as a liquid embolic agent: a study in rabbits].

Objective: To assess the effect of a liquid embolic agent 2-poly-hydroxyethyl -methacrylate (2-P-HEMA) for renal artery embolization in rabbits.

Methods: The precipitation time of different concentrations (2%, 3.5%, 5%, 6.

[Effect of hypoxic radiosensitizer sodium glycididazole on long-term result of radiotherapy for nasopharyngeal carcinoma].

Objective: To evaluate the long-term effect of sodium glycididazole (CMNa) as a hypoxic radiosensitizer on the radiotherapy for nasopharyngeal carcinoma.

Methods: Between May 1999 and May 2002, 211 patients with pathologically confirmed nasopharyngeal carcinoma were randomized into group-A treated by radiotherapy plus CMNa or group-B by radiotherapy alone. The staging was determined according to 92' Fuzhou staging systerm.

[Anatomy of the sphenoidal sinus in transsphenoidal approach through a single nostril].

Objective: To study the anatomy of the sphenoid sinus for safe pituitary adenoma resection via transsphenoidal approach through a single nostril.

Methods: Eight fresh adult cadavers and the magnetic resonance images (MRI) of the sphenoidal sinus of 5 adults were observed. In anteroposterior axes, the root of the nasal columella was defined as the point O, the inferior border of the sphenoidal sinus anterior wall as point B, the superior border of the spheniodal sinus anterior wall as point C, and the midpoint of the sellar floor as point D.

[Neuronavigation-assisted microanatomical study of the facial nerve canal through the transpetrosal approach].

Objective: To study the value of neuronavigation in the transpetroal approach, and to provide anatomic data for the protection of the nerves in the facial nerve canal (FNC) during surgeries.

Methods: Simulated surgery through the transpetroal approach was performed on 16 sides of 8 adult cadaver heads with the assistance by neuronavigation. The anatomy of the facial nerve and the relationship of related structures were observed and the distances from the utmost external edge of the mastoid to different segments of the FNC were measured.

Microanatomical and neuroendoscopic studies of the internal auditory meatus and its surrounding structures.

Objective: To observe the morphology of the internal auditory meatus in relation with its surrounding structures in Chinese people, for the purpose of providing microanatomical reference for surgeries adopting retro-sigmoid approach.

Methods: The retro-sigmoid surgical approach was simulated on 5 fresh specimens of human head, in which the internal auditory meatus and its surrounding structures were observed through a neuroendoscope and a surgical microscope. The distances from the posterior inferior edge of the internal auditory meatus to the central point of the posterior edge of the sigmoid sinus and to the posterior edge of the posterior semicircular canal were measured.