Publications by authors named "Guo Zhang Xu"

Objective: To examine the association between 25-Hydroxyvitamin D (25(OH)D) levels and sleep duration among Chinese adolescents.

Subjects And Methods: A school-based cross-sectional study was conducted among Chinese adolescents in 2017. Data on a total of 800 adolescents aged 8⁻14 years was used for this study.

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Objectives: The objective of this study was to investigate the relationship between sleep duration and overweight/obesity among Chinese adolescents.

Methods: A school-based cross-sectional study was conducted among Chinese adolescents in 2016. In total, 2795 school-aged Chinese children aged 12 to 13 years participated in this study.

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Objective: To assess the association between sleep duration and physical activity and dietary behaviors among adolescents in a representative sample.

Methods: The analysis was performed using data from the 2015 Ningbo Youth Risk Behavior Survey. Associations between physical activity and dietary behaviors and sleep duration were examined on weighted data using logistic regression.

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Background: An outbreak of measles occurred in early 2014 among individuals not targeted for vaccination-adults, and infants too young to vaccinate, in Xiangshan County, Zhejiang Province, in eastern China.

Objective: We conducted an investigation to identify risk factors responsible for this outbreak and to provide evidence-based recommendations for measles elimination strategies in China.

Methods: Measles was diagnosed using national standard case definitions.

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  • The study aimed to assess the prevalence and types of HPV among women in Ningbo, China, focusing on a sample from four villages in 2012.
  • Of the 1,373 participants, 13.5% tested positive for HPV, with 13% having high-risk genotypes, and the occurrence of HPV was higher among those with more severe cervical abnormalities.
  • The most common HPV type identified was HPV52, and the research suggests that vaccines targeting HPV52, HPV58, HPV16, and HPV18 are essential for preventing cervical issues in Chinese women.
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  • The review investigated how lifestyle changes affect blood glucose levels in adults with impaired glucose tolerance (IGT).
  • Nine randomized controlled trials were analyzed, revealing that lifestyle interventions generally led to significant reductions in plasma glucose levels.
  • Both dietary and physical interventions were effective in lowering glucose levels, suggesting that modifying lifestyle can positively influence glucose management in people with IGT.
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Background: Growing body of laboratory evidence supports the beneficial effects of n-3 polyunsaturated fatty acids (PUFAs) on colorectal cancer (CRC) prevention. Epidemiologic studies investigating the relationship between n-3 PUFAs intake and risk of CRC, however, have been inconsistent. We aimed to clarify the relation by conducting a meta-analysis of prospective studies.

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  • The study analyzed the epidemiological characteristics of hand foot and mouth disease (HFMD) in Ningbo, China, using surveillance data from 2008 to 2011.
  • A total of 37,524 cases were reported, with a significant majority in children aged 5 or younger, and the incidence was highest from April to July.
  • The primary virus responsible for HFMD was identified as EV71, with distinct sub-genotypes present, while Cox A16 was also detected; overall, the disease was found to be highly endemic in the region.
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  • * Researchers obtained various gene sequences, including 20 whole genome sequences, showing high similarity (96%-99%) to known epidemic strains like A/California/04/2009.
  • * Specific mutations were identified in the HA receptor binding site and the M2 protein sequences, indicating potential resistance to antiviral drugs and providing valuable data on H1N1 virus transmission and variation in the region.
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110 children who were given the complete course of the inactivated hepatitis A vaccine (Havrix) were followed up 10 years later. Age-matched healthy children who were not inoculated served as controls. One month after two primary injections, all children were positive for serum antibody.

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Objective: To Know the antibody level of comparison in maternal-infant pairs and the change of rubella in infants, and to provide scientific basis for controlling congenital rubella syndrome.

Methods: Newborn, 3, 6, 8, 9-month infant who never had rubella and their mothers were residents in Ningbo of Zhejiang, Harbin of Heilongjiang and Jinan of Shandong were collected as objects. Their serum samples were tested by the method of ELISA.

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Aim: To determine the association of hepatitis B virus (HBV) genotypes with probable cirrhosis and fatty liver in community-based populations.

Methods: A multi-stage cluster probability sampling method was applied to recruit 10 167 subjects aged between 6 and 72 years from our epidemiological bases in Eastern China. After excluding the subjects co-infected with hepatitis C or hepatitis D viruses, the hepatitis B surface antigen (HBsAg)-positive subjects were examined for HBV genotype, serum viral load, alanine aminotransferase (ALT), hepatitis B e antigen (HBeAg) status, and ultrasonographic changes.

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  • The study analyzed typhoid and paratyphoid fever cases in Ningbo from 1988 to 2007, revealing 19,404 cases with a low fatality rate of 0.36 per thousand.
  • It found that adults aged 20-50 were most affected, with higher incidence rates during winter and spring, and noted a shift from Salmonella typhi to Salmonella paratyphi A as the dominant strain in the region.
  • The research identified contaminated raw shellfish, like oysters and hairy clams, as primary risk factors, highlighting the need for better hygiene practices and public health education.
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  • Serum samples were collected from 2,643 suspected cases of paragonimiasis in Ningbo City between 2000-2007 to assess infection rates among humans and various animal hosts.
  • Out of the samples tested, 417 showed positive antibodies, resulting in an overall seropositivity rate of 15.8%, with residents in endemic areas having a much lower rate between 2.8% to 3.2%.
  • Infection rates in the identified intermediate hosts revealed a very low rate in snails (0.05%), a high rate in crabs (31.1%), and a moderate rate in animal reservoirs (11.9%), indicating that natural habitats for the parasite still exist in the region.
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Objective: To understand the epidemiological characteristics of age distribution of measles and related policies on measles vaccines (live; MV) in infants through analyzing the antibody levels of comparison in maternal-infant pairs. Transition of immunity in infants was also studied to provide theoretic basis for measles immunization strategy and to reduce the incidence of month-old infants.

Methods: In cities of Ningbo, Harbin, and Jinan from Zhejiang, Heilongjiang and Shandong provinces, data was collected from 2004 to 2007 and analyzed regarding the epidemic situation of measles.

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A high-performance liquid chromatographic-tandem mass spectrometric (HPLC-MS-MS) method was developed and validated to determine simultaneously coumafuryl and coumateralyl in animal tissues using warfarin as an internal standard (IS). Animal tissue samples were extracted with ethyl acetate and cleaned by Oasis HLB solid-phase extraction (SPE) cartridges. After pretreatment, the separation was performed on a XDB C18 column with an isocratic mobile phase of acetic acid-ammonium acetate (5 mmol l(-1), pH = 4.

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Objective: To study the HIV infection risk perception, sexual behavior and condom use among college students who had sexual experiences.

Methods: Using data generated from a survey on AIDS related knowledge and risk perception and sexual behavior (conducted in a coast city of Zhejiang province in 2003), with a questionnaire involving self-reporting history of sexual experience. Software SPSS 12.

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Objective: To observe the effects of hepatocyte growth factor (HGF) on tubular epithelial-myofibroblast transdifferentiation (TEMT) triggered by IL-1alpha and the fibronectin secretion of TEMT.

Methods: The normal rat kidney tubular epithelial cell line (NRK52E) was cultured for six days on plastic or collagen type I-coated plates in the presence or absence of HGF or IL-1alpha. The morphology of transdifferentiation tubular cells was observed by scanning electron microscopy (SEM) and phase-contrast microscopy.

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