Jidong cognitive impairment cohort study: objectives, design, and baseline screening.

The risk of dementia increases in patients with cognitive impairment. However, it is not clear what factors contribute to the onset of dementia in those with cognitive impairment. In this prospective cohort study, we will investigate the every-five-year incidence of cognitive impairment and prognostic factors for cognitive impairment.

Meta-analysis reveals gender difference in the association of liver cancer incidence and excess BMI.

Excess body weight has a positive association with risk of liver cancer, but the gender difference in the relationship between body mass index and liver cancer risk remains uncertainty. In this work, we performed meta-analysis for excess body weight and risk of liver cancer incidence to identify the gender difference. We searched the English-languages database and the Chinese literature databases to May 12, 2017.

Distributed lag effects and vulnerable groups of floods on bacillary dysentery in Huaihua, China.

Understanding the potential links between floods and bacillary dysentery in China is important to develop appropriate intervention programs after floods. This study aimed to explore the distributed lag effects of floods on bacillary dysentery and to identify the vulnerable groups in Huaihua, China. Weekly number of bacillary dysentery cases from 2005-2011 were obtained during flood season.

[Research progress on ebola virus glycoprotein].

Ebola virus (EBOV) causes outbreaks of a highly lethal hemorrhagic fever in humans and there are no effective therapeutic or prophylactic treatments available. The glycoprotein (GP) of EBOV is a transmembrane envelope protein known to play multiple functions including virus attachment and entry, cell rounding and cytotoxicity, down-regulation of host surface proteins, and enhancement of virus assembly and budding. GP is the primary target of protective immunity and the key target for developing neutralizing antibodies.

[The cytotoxic effect and injury mechanism of deoxynivalenol on articular chondrocytes in human embryo].

Objective: This study was to explore the cytotoxic effect and the related injury mechanism of deoxynivalenol (DON) on articular chondrocytes in human embryo.

Methods: Articular cartilage cells were isolated from knees of human embryo and cultured in DMEM/F12 medium. The cells of the 4th generation were divided into five groups and incubated with varying concentrations of DON as the followings: control group and group with DON of 0.