Publications by authors named "Guo Mingbin"
Glucocorticoids (GCs) are key inducers of osteonecrosis, yet not all patients treated with GCs develop glucocorticoid-associated osteonecrosis (GAON). The factors mediating this relationship are unclear. Studies have shown that gut microbiota and their metabolites influence bone metabolism, but their role in GAON is unclear.
View Article and Find Full Text PDFObjective: Femoral head necrosis is a challenging condition in orthopaedics, and the occurrence of collapse is an important factor affecting the prognosis of femoral head necrosis. Sclerosis bands are known to influence the collapse of the femoral head, yet there is a lack of research on the biomechanical role of sclerosis bands in non-vascularized fibular grafting surgery. This study aims to evaluate the biomechanical impact of sclerosis bands in femoral head necrosis and their role in non-vascularized fibular grafting surgery (NVFG) using finite element analysis.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to explore how the sclerosis rim volume ratio (SVR) relates to the risk of femoral head collapse after non-vascularized fibular grafting (NVFG) in patients with osteonecrosis of the femoral head (ONFH).
- The researchers analyzed 57 patients who had 64 hips operated on and found that 46.88% experienced significant collapse (greater than 2 mm) post-surgery.
- Key findings revealed that the Japanese Investigation Committee classification (JIC) and SVR1 were identified as independent risk factors for collapse progression, with a predictive model yielding a strong performance in anticipating these complications post-surgery.