Nitrogen transformation and bacterial community response in O-SBR process for treating nitrogen-containing heterocyclic antibiotics.

Nitrogen heterocyclic antibiotics (NHAs) pollution poses a significant threat to aquatic ecosystems. Ozonation (O) pretreatment is beneficial for the removal of total nitrogen (TN) in antibiotics by facilitating subsequent biological treatment. However, nitrogen transformation and bacterial community responses when treating NHAs by O-coupled biological processes remain unclear.

The efficacy of early rehabilitation in enhancing vestibular compensation in mice with unilateral vestibular neurectomy by promoting cellular proliferation and glial reaction.

Acute peripheral vestibular dysfunction is associated with a variety of postural and balance disturbances. Vestibular rehabilitation training (VRT) is widely acknowledged as an effective intervention for promoting vestibular compensation. Nevertheless, the broader implementation of early VRT is hindered by an incomplete understanding of its neurobiological mechanisms.

Conference 2024: Building an innovative scientific research ecosystem for microbiome and One Health.

The Conference 2024 provides a platform to promote the development of an innovative scientific research ecosystem for microbiome and One Health. The four key components - Technology, Research (Biology), Academic journals, and Social media - form a synergistic ecosystem. Advanced technologies drive biological research, which generates novel insights that are disseminated through academic journals.

Relationship between δ-catenin expression and whole-brain small-world network in breast cancer patients before chemotherapy.

Our study aimed to investigate the relationship between δ-catenin expression and whole-brain small-world network in breast cancer patients before chemotherapy using rs-fMRI. The study was based on the hypothesis that different δ-catenin expression levels correspond to distinct brain imaging characteristics. A total of 105 pathologically confirmed breast cancer patients were collected and categorized into high δ-catenin expression (DH, 52 cases) and low expression (DL, 53 cases) groups.

Automated measurement of cardiothoracic ratio based on semantic segmentation integration model using deep learning.

The objective of this study is to investigate the efficacy of the semantic segmentation model in predicting cardiothoracic ratio (CTR) and heart enlargement and compare its consistency with the reference standard. A total of 650 consecutive chest radiographs from our center and 756 public datasets were retrospectively included to develop a segmentation model. Three semantic segmentation models were used to segment the heart and lungs.

Mitochondrial dysfunction of Astrocyte induces cell activation under high salt condition.

Excess dietary sodium can accumulate in brain and adversely affect human health. We have confirmed in previous studies that high salt can induce activation of astrocyte manifested by the secretion of various inflammatory factors. In order to further explore the effect of high salt on the internal cell metabolism of astrocytes, RNA sequencing was performed on astrocytes under high salt environment, which indicated the oxidative phosphorylation and glycolysis pathways of astrocytes were downregulated.

Optimizing a Classification Model to Evaluate Individual Susceptibility in Noise-Induced Hearing Loss: Cross-Sectional Study.

Background: Noise-induced hearing loss (NIHL), one of the leading causes of hearing loss in young adults, is a major health care problem that has negative social and economic consequences. It is commonly recognized that individual susceptibility largely varies among individuals who are exposed to similar noise. An objective method is, therefore, needed to identify those who are extremely sensitive to noise-exposed jobs to prevent them from developing severe NIHL.

Necroptosis contributes to deoxynivalenol-induced liver injury and inflammation in weaned piglets.

Background: The aim of this study was to investigate the role of necroptosis in deoxynivalenol (DON)-induced liver injury and inflammation in weaned piglets.

Methods: In Exp. 1, 12 weaned piglets were divided into 2 groups including pigs fed basal diet and pigs fed diet contaminated with 4 mg/kg DON for 21 d.

Necroptosis contributes to deoxynivalenol-induced activation of the hypothalamic-pituitary-adrenal axis in a piglet model.

The mycotoxin deoxynivalenol (DON) is highly prevalent in cereals as an immune stressor. The hypothalamic-pituitary-adrenal (HPA) axis is activated during periods of stress, and the organism is accompanied by inflammation. Necroptosis is a newly identified type of cell death.

A novel oral vaccine delivery system for enhancing stability and immune protection: bacterium-like particle with functional coating.

Bacterium-like particles (BLPs) have gained significant attention in vaccine development due to their potential as effective immune enhancers and antigen delivery systems. BLPs are generated by boiling lactic acid bacteria in an acidic solution and are devoid of proteins and nucleic acids, offering advantages in terms of ease of preparation, high safety, and good stability. Furthermore, by employing protein anchor (PA), heterogeneous antigens can be efficiently displayed on the surface of BLPs, resulting in enhanced delivery effectiveness.

Greatly Enhanced Oxygen Reduction Reaction in Anion Exchange Membrane Fuel Cell and Zn-Air Battery via Hole Inner Edge Reconstruction of 2D Pd Nanomesh.

Platinum group metals (PGM) have yet to be the most active catalysts in various sustainable energy reactions. Their high cost, however, has made maximizing the activity and minimizing the dosage become an urgent priority for the practical applications of emerging technologies. Herein, a novel 2D Pd nanomesh structure possessing hole inner reconstructed edges (HIER) with exposed high energy facets and overstretched lattice parameters is fabricated through a facile room-temperature reduction method at gram-scale yields.

Core-Shell Engineered Fillers Overcome the Electrical-Thermal Conductance Trade-Off.

The rapid development of modern electronic devices increasingly requires thermal management materials with controllable electrical properties, ranging from conductive and dielectric to insulating, to meet the needs of diverse applications. However, highly thermally conductive materials usually have a high electrical conductivity. Intrinsically highly thermally conductive, but electrically insulating materials are still limited to a few kinds of materials.

Enhanced carbon use efficiency and warming resistance of soil microorganisms under organic amendment.

The frequency and intensity of extreme weather events, including rapid temperature fluctuations, are increasing because of climate change. Long-term fertilization practices have been observed to alter microbial physiology and community structure, thereby affecting soil carbon sequestration. However, the effects of warming on the carbon sequestration potential of soil microbes adapted to long-term fertilization remain poorly understood.

In Situ Reconstructing NiFe Oxalate Toward Overall Water Splitting.

Surface reconstruction plays an essential role in electrochemical catalysis. The structures, compositions, and functionalities of the real catalytic species and sites generated by reconstruction, however, are yet to be clearly understood, for the metastable or transit state of most reconstructed structures. Herein, a series of NiFe oxalates (NiFe CO, x = 1, 0.

Associations of urinary phytoestrogens with all-cause and cardiovascular mortality in adults: a population-based cohort study.

Background: The overall understanding of the correlations between mortality risk and phytoestrogens in general population remains limited. We examined the association between urinary phytoestrogen levels and all-cause and cardiovascular mortality based on the National Health and Nutrition Examination Survey (NHANES).

Methods: Weighted Cox proportional hazard regression models were employed to calculate adjusted hazard ratios (HRs) and their 95% confidence intervals (CIs).

Alternative translation initiation produces synaptic organizer proteoforms with distinct localization and functions.

While many mRNAs contain more than one translation initiation site (TIS), the functions of most alternative TISs and their corresponding protein isoforms (proteoforms) remain undetermined. Here, we showed that alternative usage of CUG and AUG TISs in neuronal pentraxin receptor (NPR) mRNA produced two proteoforms, of which the ratio was regulated by RNA secondary structure and neuronal activity. Downstream AUG initiation truncated the N-terminal transmembrane domain and produced a secreted NPR proteoform sufficient in promoting synaptic clustering of AMPA-type glutamate receptors.

A feature-enhanced knowledge graph neural network for machine learning method recommendation.

Large amounts of machine learning methods with condensed names bring great challenges for researchers to select a suitable approach for a target dataset in the area of academic research. Although the graph neural networks based on the knowledge graph have been proven helpful in recommending a machine learning method for a given dataset, the issues of inadequate entity representation and over-smoothing of embeddings still need to be addressed. This article proposes a recommendation framework that integrates the feature-enhanced graph neural network and an anti-smoothing aggregation network.

Diagnostic performance of MRI-based radiomics models using machine learning approaches for the triple classification of parotid tumors.

Rationale And Objectives: Preoperative differentiation of malignant tumors (MT), pleomorphic adenomas (PA), and other benign tumors of the parotid gland is critical to clinical strategy, this study aimed to develop and validate a T2-weighted image (T2WI) based radiomics model through machine learning approaches for the triple classification of parotid gland tumors.

Materials And Methods: We retrospectively enrolled 147 patients from January 2010 to July 2022. T2WIs were used to extract radiomics features.

Cooperative dynamic polaronic picture of diamond color centers.

Polarons can control carrier mobility and can also be used in the design of quantum devices. Although much effort has been directed into investigating the nature of polarons, observation of defect-related polarons is challenging due to electron-defect scattering. Here we explore the polaronic behavior of nitrogen-vacancy (NV) centers in a diamond crystal using an ultrafast pump-probe technique.

Flaxseed Oil Attenuates Intestinal Damage by Regulating Ferroptosis Signaling Pathway Following LPS Challenge in Piglets.

Scope: Ferroptosis has been demonstrated to play an important role in various tissue injuries and diseases. Flaxseed oil (FO) has been proven to have benefits for intestinal health. This study aims to explore whether FO relieved lipopolysaccharide (LPS)-induced intestinal injury through modulating ferroptosis signaling pathway.

N, S Co-Doped Carbon Nanotubes Loaded With Cu Nanoclusters For Efficient Oxygen Reduction Reaction.

Developing highly superior precious-metal-free electrocatalysts for oxygen reduction reaction (ORR) are challenging and great significance. In this study, it is reported that an efficient ORR catalysts with N and S co-doped carbon nanotubes anchored to copper (Cu) nanoclusters by mechanical grinding and high temperature heat treatment. The obtained Cu-S-N-C electrocatalysts exhibited a high ORR performance with an onset potential (Eonest) of 0.

Recent advances of doping strategy for boosting the electrocatalytic performance of two-dimensional noble metal nanosheets.

Benefiting from the ultrahigh specific surface areas, massive exposed surface atoms, and highly tunable microstructures, the two-dimensional (2D) noble metal nanosheets (NSs) have presented promising performance for various electrocatalytic reactions. Nevertheless, the heteroatom doping strategy, and in particular, the electronic structure tuning mechanisms of the 2D noble metal catalysts (NMCs) yet remain ambiguous. Herein, we first review several effective strategies for modulating the electrocatalytic performance of 2D NMCs.

Chilling stress response in tobacco seedlings: insights from transcriptome, proteome, and phosphoproteome analyses.

Tobacco ( L.) is an important industrial crop, which is sensitive to chilling stress. Tobacco seedlings that have been subjected to chilling stress readily flower early, which seriously affects the yield and quality of their leaves.