Publications by authors named "Guo Dong Jiang"
Two new sesquiterpenes ( and ) together with seven known compounds (-) were isolated from the whole plant of Hemsl. The chemical structures were established elucidated by extensive spectroscopic analysis and comparison with the literature. All compound were tested for antimicrobial activity.
View Article and Find Full Text PDFBased on structural elucidation of natural and hydrolyzed glycans, the general glycans profiling of D. officinale were unequivocally established for the first time as follows: The results indicated that the structure of D. officinale glycans with low degree of polymerization (DP ≤ 22) was linear α-D-1,4-glucan, whereas the structure of glycans with high degree of polymerization (DP > 24) was linear acetylated 1,4-glucomannan.
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- * The structures of these compounds were determined using advanced spectroscopic methods, including NMR and mass spectrometry.
- * The new compounds demonstrated significant inhibitory effects on HepG2 cancer cells, with IC values comparable to the positive control cisplatin, indicating potential for cancer treatment.
Article Synopsis
- * Advanced techniques like IR, NMR, and ECD calculations were used to determine the structures of these compounds.
- * The compounds were tested for their effects on cancer cell growth, revealing that some, particularly compounds 7 and 15, had strong inhibitory effects on A549 cells, while others showed varying levels of activity against H1299 and HepG2 cancer cells.
A simple ultrasound-assisted co-precipitation method was developed to prepare magnetic Fe3O4/graphene oxide (Fe3O4/ GO) nanoparticles. The characterization with transmission electron microscope (TEM) indicated that the products possessed small particle size. The hysteresis loop of the dried Fe3O4/GO nanoparticles demonstrated that the sample had typical features of superparamagnetic material.
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