Publications by authors named "Guo Chunlei"

The ATP-binding cassette (ABC) gene family comprises some of the most critical transporter proteins in plants, playing vital roles in maintaining cellular homeostasis and adapting to environmental changes. While ABC transporters have been extensively characterized in various plant species, their profile in C. mollissima remains less understood.

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  • Lactate is now recognized as more than just a metabolic waste product, playing essential roles in various physiological and pathological processes including inflammation, hypoxia, and tumor dynamics.
  • It influences immune cell functions by activating specific transporters and receptors, leading to immunosuppressive effects and altering immune responses in conditions like cancer and inflammation.
  • Research highlights lactate’s complex effects on immune cell regulation, suggesting it could inform new approaches to diagnosing and treating inflammatory diseases and cancers.
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  • The study aims to validate the 2019 US risk-based guidelines for cervical cancer screening specifically for Chinese women using data from over 10,000 cases.
  • Analysis revealed that the guidelines effectively recommended appropriate actions, with high sensitivity (87.1%) and specificity (82.5%) for detecting advanced cervical lesions (CIN2+ and CIN3+) while also effectively identifying lower-risk cases.
  • Overall, the findings suggest that the US risk-based guidelines are applicable and reliable for cervical cancer screening in China, indicating their potential to enhance public health efforts in this area.
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Flavonoids are crucial secondary metabolites that possess the ability to mitigate UV damage and withstand both biotic and abiotic stresses. Therefore, it is of immense significance to investigate the flavonoid content as a pivotal indicator for a comprehensive assessment of chestnut's drought tolerance. This study aimed to determine the flavonoid content and drought tolerance-related physiological and biochemical indices of six chestnut varieties (clones) grafted trees-Qianxi 42 (QX42), Qinglong 45 (QL45), Yanshanzaofeng (YSZF), Yanzi (YZ), Yanqiu (YQ), and Yanlong (YL)-under natural drought stress.

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Background: In order to improve taVNS efficacy, the usage of fMRI to explore the predictive neuroimaging markers would be beneficial for screening the appropriate MDD population before treatment.

Methods: A total of 86 MDD patients were recruited in this study, and all subjects were conducted with the clinical scales and resting-state functional magnetic resonance imaging (fMRI) scan before and after 8 weeks' taVNS treatment. A two-stage feature selection strategy combining Machine Learning and Statistical was used to screen out the critical brain functional connections (FC) that were significantly associated with efficacy prediction, then the efficacy prediction model was constructed for taVNS treating MDD.

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Ratiometric near-infrared fluorescent pH probes with various p values were innovatively designed and synthesized based on cyanine with a diamine moiety. The photochemical properties of these probes were thoroughly evaluated. Among the series, IR-PHA exhibited an optimal p value of approximately 6.

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  • There is a lack of population-based research on how HPV infection affects the vaginal environment, which can influence the risk of long-term HPV infections.
  • The study aims to explore the relationship between vaginal microbiota and vaginal metabolites in response to changes in HPV infection status.
  • Findings suggest that analyzing the vaginal metabolome could be a more effective way to assess the effects of HPV infection on the vaginal microenvironment than looking at vaginal microbiota alone.
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The atomic-level structure and electronic properties of monazite were investigated using a first-principles method based on density functional theory (DFT). First, the geometric structure of monazite was optimized, followed by calculations of its Mulliken population, electron density, and density of states, which were subsequently analyzed. The findings of this analysis suggest that monazite is highly susceptible to cleavage along the {100} plane during crushing and grinding.

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This report described three cases with long-term severe dysmenorrhea, and these cases were referred to our department for medical help. The diagnosis of accessory cavitated uterine malformation (ACUM) was considered based on symptoms and ultrasound/MRI findings. Moreover, a combined approach involving hysteroscopic surgery and laparoscopic surgery was undertaken, and no complications occurred during surgery and in the post-operative period.

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The NAC gene family is one of the most important transcription factor families specific to plants, responsible for regulating many biological processes, including development, stress response, and signal transduction. However, it has not yet been characterized in chestnut, an important nut tree species. Here, we identified 115 genes in the chestnut genome, which were divided into 16 subgroups based on the phylogenetic analysis.

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Background: Transcutaneous electrical cranial-auricular acupoint stimulation (TECAS) is a novel non-invasive therapy for major depressive disorder (MDD) that stimulates acupoints innervated by the trigeminal and auricular vagus nerves. However, there are few neuroimaging studies involving the TECAS for the treatment of MDD. Therefore, this study aimed to investigate the treatment response and neurological effects of TECAS using resting-state functional magnetic resonance imaging (rs-fMRI).

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Objective: To evaluate the feasibility of an internet-facilitated community model for cervical cancer screening using self-collected HPV testing as primary screening.

Method: A population-based cervical cancer screening program was conducted in the suburb of Shenzhen, China, from September 2014 to July 2017. Women with 25-60 years of age and no pregnancy were eligible for participation.

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Ferroptosis is a unique programmed cell death process that was discovered a few years ago and plays an important role in tumor biology and treatment. However, it still remains a challenge to modulate tumor ferroptosis by spatiotemporally controlled cell-intrinsic Fenton chemistry. Herein, a pH activated photothermal sensitizer IR-PE has been designed and synthesized on the basis of cyanine bearing a diamine moiety, which is capable of triggering the lysosomal dysfunction-mediated Fenton pathway under the irradiation of near-infrared light to evoke ferroptosis, thereby improving antitumor efficacy and mitigating systemic side effects.

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Low-intensity magnetic separation tailings (LIMS tailings) are a common by-product obtained after magnetite magnetic separation. In this article, various techniques such as chemical analysis, X-ray diffraction, ICP-MS, and Mineral Liberation Analysis (MLA) were employed to investigate the LIMS tailings. The primary iron-bearing mineral identified was hematite and rare earth minerals were monazite and bastnaesite.

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Background: Anhedonia is a significant predictor of disease progression and treatment outcomes in Major Depressive Disorder (MDD), linked to reward network dysfunctions. However, understanding of its underlying neural mechanisms remains limited. This study aimed to investigate the brain functional mechanisms underlying MDD with anhedonia using resting-state functional magnetic resonance imaging (rs-fMRI).

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We simulate with FDTD solutions a complete family of basic Boolean logic operations, which includes XOR, AND, OR, NOT, NOR, NAND, and XNOR, by using compact Ψ-shaped silicon-on-silica optical waveguides that are operated at a 1.55 μm telecommunications wavelength. Four identical slots and one microring resonator, all made of silicon deposited on silica, compose the adopted waveguide.

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Transcutaneous electrical cranial-auricular acupoint stimulation (TECAS) is an innovative, non-invasive therapy for major depressive disorder (MDD). However, its effectiveness and underlying neural mechanisms remain not fully understood. This study aimed to investigate the treatment response and neurological effects of TECAS compared to escitalopram, a commonly used depression medication, using resting-state functional magnetic resonance imaging (rs-fMRI).

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Atmospheric water harvesting is a sustainable solution to global water shortage, which requires high efficiency, high durability, low cost, and environmentally friendly water collectors. In this paper, we report a novel water collector design based on a nature-inspired hybrid superhydrophilic/superhydrophobic aluminum surface. The surface is fabricated by combining laser and chemical treatments.

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Structural coloring is a photostable and environmentally friendly coloring approach that harnesses optical interference and nanophotonic resonances to obtain colors with a range of applications including display technologies, colorful solar panels, steganography, décor, data storage, and anticounterfeiting measures. We show that optical coatings exhibiting the photonic Fano Resonance present an ideal platform for structural coloring; they provide full color access, high color purity, high brightness, controlled iridescence, and scalable manufacturing. We show that an additional oxide film deposited on Fano resonant optical coatings (FROCs) increases the color purity (up to 99%) and color gamut coverage range of FROCs to 61% of the CIE color space.

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Chinese chestnut () is an important nut tree species, and its embryo is rich in sugar. We combined metabolomic and transcriptomic data to analyze metabolites and genes related to sugar in two Chinese chestnut cultivars at 60, 70, 80, 90 and 100 days after flowering (DAF). The soluble sugar content of high-sugar cultivar at maturity is 1.

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In the last ten years, silicon photonics has made considerable strides in terms of device functionality, performance, and circuit integration for a variety of practical uses, including communication, sensing, and information processing. In this work, we theoretically demonstrate a complete family of all-optical logic gates (AOLGs), including XOR, AND, OR, NOT, NOR, NAND, and XNOR, through finite-difference-time-domain simulations using compact silicon-on-silica optical waveguides that operate at 1.55 μm.

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The basic helix-loop-helix (bHLH) transcription factors (TFs) gene family is an important gene family in plants, and participates in regulation of plant apical meristem growth, metabolic regulation and stress resistance. However, its characteristics and potential functions have not been studied in chestnut (), an important nut with high ecological and economic value. In the present study, 94 were identified in chestnut genome, of which 88 were unevenly distributed on chromosomes, and other six were located on five unanchored scaffolds.

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Eco-friendly, efficient, and durable electrocatalysts from earth-abundant materials are crucial for water splitting through hydrogen and oxygen generation. However, available methods to fabricate electrocatalysts are either hazardous and time-consuming or require expensive equipment, hindering the large-scale, eco-friendly production of artificial fuels. Here, we present a rapid, single-step method for producing MoS/NiF electrocatalysts with controlled sulfur-vacancies via electric-field-assisted pulsed laser ablation (EF-PLA) in liquid and deposition on nickel foam, enabling efficient water splitting.

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Background: Although the importance of miRNA variants in female reproductive disorders has been frequently reported, the association between miRNA polymorphisms and recurrent pregnancy loss (RPL) has been poorly studied. In this study, we aimed to assess the correlation of four different miRNA variants to unexplained RPL.

Methods And Results: The prevalence of four SNPs including miR-21 rs1292037, miR-155-5p rs767649, miR-218-2 rs11134527, and miR-605 rs2043556 in 280 cases with iRPL and 280 controls was performed.

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Conversion of a regular metal surface to a superhydrophobic one has great appeal because of the wide range of potential applications such as anti-fouling, anti-corrosion, and anti-icing. One promising technique is to modify surface wettability by laser processing to form nano-micro hierarchical structures with various patterns, such as pillars, grooves, and grids, followed by an aging process in the air or additional chemical processes. Surface processing is typically a lengthy process.

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