Safety and Dose-Dependent Effects of for the Treatment of Acute Cold Episodes in Children: A Multicenter, Randomized, Open-Label Clinical Trial.

Due to the frequency and severity of cold symptoms in children, and the risk of associated complications, effective treatments are urgently needed. Here we evaluated the safety profile and treatment benefits of in children with acute cold and flu symptoms. A total of 79 children (4-12 years) were randomized to a treatment regimen of three or five times daily Echinaforce Junior tablets (total of 1200 or 2000 mg extract, EFJ) for the prospective treatment of upcoming cold and flu episodes at first signs.

Superior vasodilation of human pulmonary vessels by vardenafil compared with tadalafil and sildenafil: additive effects of bosentan.

Objectives: Pulmonary arterial hypertension is characterized by pulmonary vascular proliferation and remodelling, leading to a progressive increase in pulmonary arterial resistance. Vasodilator properties of 3 different phosphodiesterase (PDE)-5 inhibitors alone and in combination with an endothelin (ET) receptor antagonist were compared in an ex vivo model.

Methods: Segments of human pulmonary arteries (PAs) and pulmonary veins (PVs) were harvested from lobectomy specimens.

Prospective randomized controlled trial to evaluate "fast-track" elective open infrarenal aneurysm repair.

Background And Aims: Fast-track programs have been introduced in many surgical fields to minimize postoperative morbidity and mortality. Morbidity after elective open infrarenal aneurysm repair is as high as 30%; mortality ranges up to 10%. In terms of open infrarenal aneurysm repair, no randomized controlled trials exist to introduce and evaluate such patient care programs.

Antiplasmodial activities of sesquiterpene lactones from Eupatorium semialatum.

Eupatorium semialatum, Plasmodium falciparum, Sesquiterpene Lactones Eupatorium semialatum is a member of the Asteraceae, which occurs in Guatemala. Previously, we reported the occurrence of sesquiterpene lactones of the eudesmanolide type as main constituents in the leaves. This paper deals with the isolation and identification of the first guaianolide found in E.

Thoracoscopy versus thoracotomy: a prospective comparison of trauma and quality of life.

Background: Reliable comparisons of thoracoscopy (TCC) and anterolateral thoracotomy (ATT) with regard to trauma and post-operative quality of life are rare. This study was conducted to quantify the results of TCC, which was expected to show an advantage.

Methods: Using a matched-pair design (matching criteria: comparable intracavitary procedure, benign/malignant disease and sex), 22 patients were compared who underwent either TCC or ATT (Wilcoxon matched-pairs signed-ranks test, P<0.

Retention and stability--taking various treatment parameters into account.

Patients And Method: In order to assess stability after orthodontic treatment, 132 patients who had been treated by one orthodontist in private practice were examined 6 years on average after completion of their treatment. Therapeutically induced movements and post-therapeutic changes were measured using dental casts, and the number of cases which had relapsed was calculated as a percentage of the individual measurements. The extent of post-therapeutic changes in patients with and without long-term retention was analyzed together with possible correlations with retention time and retainer type.