Xerostomia in 75-85-year-olds: A longitudinal population study.

Background: Xerostomia can pose significant problems for many elderly people.

Objectives: To investigate longitudinal changes in prevalence, persistence, progression, remission and incidence of xerostomia from age 75 to 85 years.

Methods: All 75-year-olds (born 1932) from two Swedish counties, Sweden were mailed a questionnaire in 2007 (N = 5195), and again in 2017 when they were aged 85 (N = 3323).

Topological data analysis in medical imaging: current state of the art.

Machine learning, and especially deep learning, is rapidly gaining acceptance and clinical usage in a wide range of image analysis applications and is regarded as providing high performance in detecting anatomical structures and identification and classification of patterns of disease in medical images. However, there are many roadblocks to the widespread implementation of machine learning in clinical image analysis, including differences in data capture leading to different measurements, high dimensionality of imaging and other medical data, and the black-box nature of machine learning, with a lack of insight into relevant features. Techniques such as radiomics have been used in traditional machine learning approaches to model the mathematical relationships between adjacent pixels in an image and provide an explainable framework for clinicians and researchers.

Temporal changes and gender differences related to orofacial symptoms in two cohorts of 75-year-old Swedish subjects examined in 2007 and 2017: A repeated cross-sectional study.

Objectives: To compare two cohorts of 75-year-old persons, born 10 years apart, in regard to reported symptoms related to temporomandibular disorders (TMD) and orofacial complaints with special reference to gender differences.

Material And Methods: In 2007, a questionnaire comprising questions on social factors, general and oral health, and a series of attitude-related questions was mailed to all individuals born in 1932 living in two Swedish counties (N = 5195), and in 2017 to all born in 1942 (N = 7204). The response rate for the cohort examined in 2007 was 71.

Comparative study of left atrium epicardial fat tissue pattern using persistent homology approach.

Objective: Atrial Fibrillation (A-fib) is an abnormal heartbeat condition in which the heart races and beats in an uncontrollable way. It is observed that the presence of increased epicardial fat/fatty tissue in the atrium can lead to A-fib. Persistent homology using topological features can be used to recapitulate enormous amounts of spatially complicated medical data into a visual code to identify a specific pattern of epicardial fat tissue with non-fat tissue.

Satisfaction with dental appearance in two cohorts of 75-year-olds examined in 2007 and 2017: A repeated cross-sectional study.

Background: Satisfaction with dental appearance plays an important role in the self-esteem and psychological well-being of the elderly, the significance of which the attending dentist may not always be fully cognisant of.

Objectives: To assess the level of satisfaction with dental appearance, its associated factors and temporal changes in two cohorts of 75-year-old Swedes born 10 years apart.

Methods: In 2007, a questionnaire was mailed to all those living in Örebro and Östergötland counties, Sweden, who were born in 1932 (n = 5195), and in 2017 to all born in 1942 (n = 7204).

Prediction of xerostomia in a 75-year-old population: A 25-year longitudinal study.

Objectives: To follow the same individuals from age 50 up to 75 years to report on prevalence, persistence, progression, remission, incidence and predictors for xerostomia.

Methods: A questionnaire was distributed to all 50-years-olds (1992) in two Swedish counties (N = 8888) and repeated at the age of 65 (2007) and 75 years (2017). 3060 individuals responded on all three occasions (response rate 42.

Changes in conditions related to reported oral and general health over a ten-year period as reflected in two cohorts of 75-year-old subjects examined in 2007 and 2017.

Background: The rapidly ageing and increasingly dentate population puts great demands on society regarding the provision of adequate medical and dental care facilities.

Objectives: To present changes in reported demographic, general and oral health factors in two cohorts of 75 year olds in 2007 and 2017, and to analyse factors associated with self-reported number of remaining teeth and chewing efficiency.

Material And Methods: All 75-year-old people living in two Swedish counties received a questionnaire in 2007 and in 2017.

Self-reported dry mouth in 50- to 80-year-old Swedes: Longitudinal and cross-sectional population studies.

Xerostomia is a common condition among elderly. The objectives were to examine prevalence, persistence, progression, yearly incidence of xerostomia, associated background factors and its influence on oral impacts on daily performances (OIDP) in 50- to 80-year-old people. In 1992, a questionnaire was sent to all 50-year-old (n = 8888) and in 2007 to all 75-year-old persons (n = 5195) living in two Swedish counties.

A 3-year study of patients with tinnitus and jaw muscle tenderness.

This study evaluated three-year results of treatment with an interocclusal appliance in 89 tinnitus patients with jaw muscle tenderness. Subjective tinnitus severity was recorded using a visual analog scale (VAS). The number of tender muscles was registered.

An International Survey among Prosthodontists of the Use of Mandibular Implant-Supported Dental Prostheses.

Purpose: To evaluate the use of implant-supported overdentures (IOD) and implant-supported fixed dental prostheses (IFDP) in patients with edentulous mandibles among international prosthodontists.

Materials And Methods: A questionnaire was sent by e-mail to all clinically active prosthodontists in the International College of Prosthodontists with questions related to implant treatment of the edentulous mandible performed in 2015.

Results: One hundred and sixteen prosthodontists from 33 countries responded to the questionnaire.

Uncovering precision phenotype-biomarker associations in traumatic brain injury using topological data analysis.

Background: Traumatic brain injury (TBI) is a complex disorder that is traditionally stratified based on clinical signs and symptoms. Recent imaging and molecular biomarker innovations provide unprecedented opportunities for improved TBI precision medicine, incorporating patho-anatomical and molecular mechanisms. Complete integration of these diverse data for TBI diagnosis and patient stratification remains an unmet challenge.

Zirconia abutments for single-tooth implant restorations: a 10- to 11-year follow-up study.

Objectives: To evaluate the clinical outcome of custom-made zirconia abutments for implant-supported single-tooth restorations 10-11 years after insertion.

Material And Methods: The study comprises a clinical examination of 23 patients with 30 restorations placed 10-11 years ago. Oral surgeons placed the implants.

Some issues related to evidence-based implantology.

This article reviews relevant dental literature to answer some frequent questions related to evidence-based implantology. There are hundreds of implant systems on the market, but the majority lack clinical documentation. Recommended number of implants for full-arch fixed prostheses is four or five in the mandible but at least six in the maxilla.

Implant and root supported overdentures - a literature review and some data on bone loss in edentulous jaws.

Purpose: To present a literature review on implant overdentures after a brief survey of bone loss after extraction of all teeth.

Materials And Methods: Papers on alveolar bone loss and implant overdentures have been studied for a narrative review.

Results: Bone loss of the alveolar process after tooth extraction occurs with great individual variation, impossible to predict at the time of extraction.

Is there a trend of decreasing prevalence of TMD-related symptoms with ageing among the elderly?

Objective: Older adults have not been studied as much as younger ones regarding prevalence of TMD-related symptoms. The aim was to assess the prevalence of TMD-related symptoms in two population samples, 70 and 80 years old.

Materials And Methods: Identical questionnaires were in 2012 sent to all subjects born in 1932 and 1942 living in two Swedish counties.

Use of implant-supported prostheses in edentulous mandibles among prosthodontists in Sweden.

The aim of this study was to investigate the production of mandibular implant-supported fixed and removable prostheses among prosthodontic specialists in Sweden and to compare the results with findings in a similar study made in 2001 (17). Questionnaires regarding treatment with mandibular implant prostheses during 20011 were mailed to all specialists in prosthodontics in Sweden (n = 156, according to available data). Of the 156 questionnaires, 129 (83%) were returned and of those 114 were completed.

Management of tinnitus and jaw-muscle tenderness using an intraoral appliance and acupuncture.

Associations between signs and symptoms from the masticatory system and tinnitus have been reported.The aim of the study was to evaluate the effect of intraoral splint therapy and acupuncture on jaw-muscle tenderness and tinnitus. The study comprised 45 patients (24 men, 21 women; mean age 48 +/- 12 years) with long-standing tinnitus (duration 6.

Treatment with implant-supported fixed dental prostheses in patients with congenital and acquired neurologic disabilities: a prospective study.

Purpose: To study the medium- to long-term outcome of implant treatment in patients with neurologic disabilities.

Materials And Methods: Twenty-seven patients with different disabilities and in need of prosthodontic treatment were treated with various implant-supported prostheses. Altogether, 88 threaded titanium implants were placed.

Persistent topology and metastable state in conformational dynamics.

The large amount of molecular dynamics simulation data produced by modern computational models brings big opportunities and challenges to researchers. Clustering algorithms play an important role in understanding biomolecular kinetics from the simulation data, especially under the Markov state model framework. However, the ruggedness of the free energy landscape in a biomolecular system makes common clustering algorithms very sensitive to perturbations of the data.

Building Markov state models with solvent dynamics.

Background: Markov state models have been widely used to study conformational changes of biological macromolecules. These models are built from short timescale simulations and then propagated to extract long timescale dynamics. However, the solvent information in molecular simulations are often ignored in current methods, because of the large number of solvent molecules in a system and the indistinguishability of solvent molecules upon their exchange.

What is the evidence base for the efficacies of different complete denture impression procedures? A critical review.

Objectives: Many procedures used in prosthodontics, including the materials and methods used for complete denture impressions, lack support of good evidence. The aims were to systematically, and critically, review the literature on complete denture impression materials and methods to identify an impression procedure that can be considered expedient for achieving a satisfactory clinical outcome for complete denture wearers.

Data And Sources: MEDLINE/PubMed and the Cochrane Library were searched for studies on impression procedures used in the clinical fabrication of complete dentures.

Dental erosion and its growing importance in clinical practice: from past to present.

Since the mid-1990s, the focus of studies on tooth wear has steadily shifted from the general condition towards the more specific area of dental erosion; equally, a shift has occurred from studies in adults to those in children and adolescents. During this time, understanding of the condition has increased greatly. This paper attempts to provide a critical overview of the development of this body of knowledge, from earlier perceptions to the present.

A 5-year retrospective study of survival of zirconia single crowns fitted in a private clinical setting.

Objectives: The aim of this report was to evaluate the 5-year clinical performance and survival of zirconia (NobelProcera™) single crowns.

Methods: All patients treated with porcelain-veneered zirconia single crowns in a private practice during the period October 2004 to November 2005 were included. The records were scrutinized for clinical data.